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The map label for this gene is moeB [H]

Identifier: 53718080

GI number: 53718080

Start: 481272

End: 482030

Strand: Reverse

Name: moeB [H]

Synonym: BPSL0441

Alternate gene names: 53718080

Gene position: 482030-481272 (Counterclockwise)

Preceding gene: 53718081

Following gene: 53718072

Centisome position: 11.83

GC content: 68.77

Gene sequence:

>759_bases
ATGAACGACGAACAACTCCTCCGCTATTCCCGCCACATCCTCGTCGACGAGATCGGCATCGAGGCGCAGCAGCGCTTTCT
CGACGCGCACGCGATCGTCGTCGGCGCGGGCGGGCTCGGTTCGCCCGCCGCGATGTATCTCGCGGCGGCGGGCGTCGGCA
CAATCACGCTCGTCGATGCCGACACCGTCGATCTCACGAACCTGCAGCGGCAGATCCTGCACGCGACGGATTCGGTCGGC
CGCAAGAAGGTCGAATCGGGCCGCGACGCGCTCGCGCGGCTCAATCCGGACGTGAAGGTGAACGCGGTCGCCGAGCGCGT
CGACGACGCGTGGCTGAACGCGCACGTGCCGCACGCGAGCGTCGTGCTCGACTGCACCGACAACTTCGCGACGCGCCACG
CGATCAACCGCGCGTGCGTCGCGCATCGCGTGCCGCTCGTATCGGGTGCGGCGCTGCGCTTCGACGGGCAGATCAGCACA
TTCGATTTCCGCGAGCCCGGCTCGCCGTGCTACGCGTGCGTGTTCCCGGAGGATCAGCCGTTCGAGGAAGTCGCGTGCTC
GACGATGGGCGTGTTCGCGCCGACCGTCGGCATCATCGGCGCGATGCAGGCGGCCGAGGCGCTGCGCGTGATCGGCGGCA
TCGGCGCGACGCTCGTCGGCCGGCTGATGATGCTCGATTCGCTGCGGATGGAATGGAACACGATGAAGATCGCACGGCAG
CCGGATTGCCCGGTGTGCGGCGCGGGCGGCGCGCATTGA

Upstream 100 bases:

>100_bases
GCGACGCCGTGCACGGGCCATCGCGGCGAGCCGCCGCGATGGCCCGTTTTCTTTGCGCGCCTAAAATAACAATCGAGACA
GTTTCCCCCGCCGCCGCACG

Downstream 100 bases:

>100_bases
GCGAAGCAGCCCGGCCGGCCGCCGCTACCGCTGCGGCAGTGGACACGCGCGGCCGTCGGCCCGGGCGACGGTGATGATGG
CTGCGTCTGCGTCTGCGTCT

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAAAGVGTITLVDADTVDLTNLQRQILHATDSVG
RKKVESGRDALARLNPDVKVNAVAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQIST
FDFREPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGATLVGRLMMLDSLRMEWNTMKIARQ
PDCPVCGAGGAH

Sequences:

>Translated_252_residues
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAAAGVGTITLVDADTVDLTNLQRQILHATDSVG
RKKVESGRDALARLNPDVKVNAVAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQIST
FDFREPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGATLVGRLMMLDSLRMEWNTMKIARQ
PDCPVCGAGGAH
>Mature_252_residues
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAAAGVGTITLVDADTVDLTNLQRQILHATDSVG
RKKVESGRDALARLNPDVKVNAVAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQIST
FDFREPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGATLVGRLMMLDSLRMEWNTMKIARQ
PDCPVCGAGGAH

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=249, Percent_Identity=40.5622489959839, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI4885649, Length=167, Percent_Identity=29.940119760479, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=44.8, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI87082356, Length=252, Percent_Identity=44.8412698412698, Blast_Score=207, Evalue=4e-55,
Organism=Escherichia coli, GI1789177, Length=150, Percent_Identity=38.6666666666667, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540406, Length=260, Percent_Identity=40.3846153846154, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI193203301, Length=166, Percent_Identity=27.1084337349398, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86565433, Length=144, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86565431, Length=144, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508819, Length=184, Percent_Identity=33.1521739130435, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=252, Percent_Identity=36.1111111111111, Blast_Score=156, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322639, Length=160, Percent_Identity=28.125, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320598, Length=166, Percent_Identity=27.1084337349398, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582879, Length=250, Percent_Identity=40.8, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24660640, Length=159, Percent_Identity=32.7044025157233, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573937, Length=159, Percent_Identity=28.9308176100629, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26873; Mature: 26873

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAAAGVGTITLVDA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCEEEEEEC
DTVDLTNLQRQILHATDSVGRKKVESGRDALARLNPDVKVNAVAERVDDAWLNAHVPHAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCE
VVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQISTFDFREPGSPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGATLVGRLMMLDSLRMEWNTMKIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECC
PDCPVCGAGGAH
CCCCCCCCCCCC
>Mature Secondary Structure
MNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAAAGVGTITLVDA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCEEEEEEC
DTVDLTNLQRQILHATDSVGRKKVESGRDALARLNPDVKVNAVAERVDDAWLNAHVPHAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCE
VVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQISTFDFREPGSPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGATLVGRLMMLDSLRMEWNTMKIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECC
PDCPVCGAGGAH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]