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The map label for this gene is ggt [H]

Identifier: 53718055

GI number: 53718055

Start: 449010

End: 450893

Strand: Reverse

Name: ggt [H]

Synonym: BPSL0416

Alternate gene names: 53718055

Gene position: 450893-449010 (Counterclockwise)

Preceding gene: 53718057

Following gene: 53718051

Centisome position: 11.07

GC content: 73.73

Gene sequence:

>1884_bases
ATGACCGACCGGATTCGTCCGCGCCCCTTCCGCTCGCGAGCCGGCGCGATCGCCGCCGCCTTCTTCGCCGTCGCCGCCGC
CGGATGCGCGAACGCGCCCGGCCCGGGCGCGCAGAACGCCGCCGCGCCGGCCTCGGCCGCTTCCACGCCGCCGGCGGCGC
CGAGCGCCGAAGCCCCGGCCGCGCCCGCCGAGCTGTCGAGTTGGGTCGACAAGCCGGGCTGGACCGCGCAGCGCGACATG
ATCGCGGCCGCGCATCCGCTCGCCGCGCAAGCCGGCCAGGCAATGCTCAAGGCGGGCGGCACCGCCGTCGATGCGGCGAT
CGCCGCGCAGATGGTGCTGATGCTCGTCGAGCCGCAGGCGTCGGGCATCGGCGGCGGCGCGTTCCTGTTGCACGCGAACG
GCAAGACGATCGAAGCCTATGACGGCCGTGAAACCGCGCCCGCCGCCGCCACCGACCGCCTCTTCCTCGATGCGAACGGC
AAGCCGCTGCCGCGCGCGGCGCTCGGCGCGCGCACGGTCGGCGCGCCGGGCGCGCTGCGGATGCTCGAGCTCGCGCATCG
CGCGCACGGCAAGCTGCCATGGCGGCGCCTGTTCCAGCCCGCGATCCGGCTCGCCGAGCAAGGCTTTCCGCTCGGCCCGC
GGCTCGCGGCGGCGCTCGCGAACGAGCCGTCGCTCGCGCGCGATCCGGCCGCGCGCGCGTACTTCTACGACCGGAACGGC
GCGCCGAAACCGGCCGGCACGACGCTGAAGAACCCTCAGCTCGCGGCCACGCTCAGGCTCGTCGCCGCGCACGGCGCGAA
CGCGTTCTATACCGGCGCGATCGCGCGCGACATCGTCGCGACAGTCCGGCAGGCGCCGAATCCGGGCGTGCTGAGCATGC
AGGACCTCGCGCAATACCGTGCGAAGACGCGCGAGCCGCTGTGCGCCGACTATCGCAAATGGACCGTGTGCGGGATGCCG
CCGCCGTCGGCGGGCGGGCTCGTCGTCGCGCAGATTCTCGGGCTGCTCGAGGCGCAGCCGGACTGGCGGCAGATCGGCGC
GCAAAAACCCGTGCGCAATGCGGTGGGCGTCGAGCCGACGCCGTTCGCCGCGCATCTGTTCAGCGAGGCGGGCCGGCTCG
CGTACGCGGACCGCGCGCAGTACGTTGCCGATCCCGATTTCGTCGCGCCGCCGGGCGGCAGTTGGAAGCGCCTCGTCGAG
CGGCGCTACGTCGCCGAACGCGCGCGGCTGATCGGCGACGCGAGCGCGGGCGAGGCGAGCGCCGGCTCGCCGTCCGGCCT
GCCGCCCGCGACCGCCGCCGATCGCGGCGCGGAGCCGCCGTCGGGATCGCAGATCACCGTCGTCGATCGCTACGGCAATG
CGGTATCGATGGCGTCGACGCTCGACGAGCGCTTCGGCTCGCGGCTGATGGTGCGCGGCTTCCTGCTCAACAGCCAGTTG
CTCGATTTCTCGCCCGCGTCGGCCGAGCACGGCAAGCCGGTCGCGAATCGCGTGCAGCCGGGCAAGCGCGCGCGCTCGAC
GCTCGCGCCCGAGCTCGTATTCGAGAAAGGCTCGTCGCGGCTGATGATGGCGCTCGGCTCGGCGGGCGGCGCTTCCACCG
CGAACGACGTCGCGAAAACGCTCGTCGGGATGATCGACTGGGGCATGACGATGCAGCAGGCGATCGCGCTGCCGAACTTC
GGATCGCGCAACGGGCCGACCGAGCTCGAGCAAGGGCGCGTGTCCGATGCGCTCGCCGGCGCGCTGAAGGCGCGCGGGCA
CGACGTGCGCGTCGTCGAGCTCGGGTCGAGCCTGCAGGGGATCCAGCGGATCAACGTGGAGGGGCAGTCAGTGTGGTTCG
GCGGCTCGGACCCGCGGCGCGACGGGATCGTCGCCGGAGACTGA

Upstream 100 bases:

>100_bases
GACACGGCGACAATACCCCGCCCGCGCGCCGCCGCACGGGCGTTCGCATCCTGCGGCGGGGGCCGCCCGCCGCCGTTCTT
TCGTTCGCACCGAGGTATTC

Downstream 100 bases:

>100_bases
ACGTCTCGCCGCGCGCGTGCGCGAGATCACGGGCGGCGCGGGCGCGCGGGTCGCGTTCGACCCCGTCGCGGGCGCGCTGC
TGCCGCAACTGGCCGATGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MTDRIRPRPFRSRAGAIAAAFFAVAAAGCANAPGPGAQNAAAPASAASTPPAAPSAEAPAAPAELSSWVDKPGWTAQRDM
IAAAHPLAAQAGQAMLKAGGTAVDAAIAAQMVLMLVEPQASGIGGGAFLLHANGKTIEAYDGRETAPAAATDRLFLDANG
KPLPRAALGARTVGAPGALRMLELAHRAHGKLPWRRLFQPAIRLAEQGFPLGPRLAAALANEPSLARDPAARAYFYDRNG
APKPAGTTLKNPQLAATLRLVAAHGANAFYTGAIARDIVATVRQAPNPGVLSMQDLAQYRAKTREPLCADYRKWTVCGMP
PPSAGGLVVAQILGLLEAQPDWRQIGAQKPVRNAVGVEPTPFAAHLFSEAGRLAYADRAQYVADPDFVAPPGGSWKRLVE
RRYVAERARLIGDASAGEASAGSPSGLPPATAADRGAEPPSGSQITVVDRYGNAVSMASTLDERFGSRLMVRGFLLNSQL
LDFSPASAEHGKPVANRVQPGKRARSTLAPELVFEKGSSRLMMALGSAGGASTANDVAKTLVGMIDWGMTMQQAIALPNF
GSRNGPTELEQGRVSDALAGALKARGHDVRVVELGSSLQGIQRINVEGQSVWFGGSDPRRDGIVAGD

Sequences:

>Translated_627_residues
MTDRIRPRPFRSRAGAIAAAFFAVAAAGCANAPGPGAQNAAAPASAASTPPAAPSAEAPAAPAELSSWVDKPGWTAQRDM
IAAAHPLAAQAGQAMLKAGGTAVDAAIAAQMVLMLVEPQASGIGGGAFLLHANGKTIEAYDGRETAPAAATDRLFLDANG
KPLPRAALGARTVGAPGALRMLELAHRAHGKLPWRRLFQPAIRLAEQGFPLGPRLAAALANEPSLARDPAARAYFYDRNG
APKPAGTTLKNPQLAATLRLVAAHGANAFYTGAIARDIVATVRQAPNPGVLSMQDLAQYRAKTREPLCADYRKWTVCGMP
PPSAGGLVVAQILGLLEAQPDWRQIGAQKPVRNAVGVEPTPFAAHLFSEAGRLAYADRAQYVADPDFVAPPGGSWKRLVE
RRYVAERARLIGDASAGEASAGSPSGLPPATAADRGAEPPSGSQITVVDRYGNAVSMASTLDERFGSRLMVRGFLLNSQL
LDFSPASAEHGKPVANRVQPGKRARSTLAPELVFEKGSSRLMMALGSAGGASTANDVAKTLVGMIDWGMTMQQAIALPNF
GSRNGPTELEQGRVSDALAGALKARGHDVRVVELGSSLQGIQRINVEGQSVWFGGSDPRRDGIVAGD
>Mature_626_residues
TDRIRPRPFRSRAGAIAAAFFAVAAAGCANAPGPGAQNAAAPASAASTPPAAPSAEAPAAPAELSSWVDKPGWTAQRDMI
AAAHPLAAQAGQAMLKAGGTAVDAAIAAQMVLMLVEPQASGIGGGAFLLHANGKTIEAYDGRETAPAAATDRLFLDANGK
PLPRAALGARTVGAPGALRMLELAHRAHGKLPWRRLFQPAIRLAEQGFPLGPRLAAALANEPSLARDPAARAYFYDRNGA
PKPAGTTLKNPQLAATLRLVAAHGANAFYTGAIARDIVATVRQAPNPGVLSMQDLAQYRAKTREPLCADYRKWTVCGMPP
PSAGGLVVAQILGLLEAQPDWRQIGAQKPVRNAVGVEPTPFAAHLFSEAGRLAYADRAQYVADPDFVAPPGGSWKRLVER
RYVAERARLIGDASAGEASAGSPSGLPPATAADRGAEPPSGSQITVVDRYGNAVSMASTLDERFGSRLMVRGFLLNSQLL
DFSPASAEHGKPVANRVQPGKRARSTLAPELVFEKGSSRLMMALGSAGGASTANDVAKTLVGMIDWGMTMQQAIALPNFG
SRNGPTELEQGRVSDALAGALKARGHDVRVVELGSSLQGIQRINVEGQSVWFGGSDPRRDGIVAGD

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=561, Percent_Identity=32.4420677361854, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI73915090, Length=561, Percent_Identity=32.4420677361854, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI73915096, Length=561, Percent_Identity=32.4420677361854, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI73915094, Length=561, Percent_Identity=32.4420677361854, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI113429324, Length=561, Percent_Identity=31.9073083778966, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI113429326, Length=566, Percent_Identity=31.6254416961131, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI153266885, Length=569, Percent_Identity=29.1739894551845, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI153266901, Length=570, Percent_Identity=29.2982456140351, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI109148539, Length=541, Percent_Identity=29.9445471349353, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI153266907, Length=567, Percent_Identity=27.336860670194, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI30581157, Length=192, Percent_Identity=30.2083333333333, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI30581155, Length=192, Percent_Identity=30.2083333333333, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1789856, Length=569, Percent_Identity=35.5008787346221, Blast_Score=277, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI193208247, Length=510, Percent_Identity=30, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI193208245, Length=510, Percent_Identity=30, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17542894, Length=550, Percent_Identity=31.0909090909091, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI212646519, Length=510, Percent_Identity=29.4117647058824, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI72000294, Length=510, Percent_Identity=29.4117647058824, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17506189, Length=559, Percent_Identity=27.906976744186, Blast_Score=175, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI72001497, Length=226, Percent_Identity=28.3185840707965, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72001495, Length=227, Percent_Identity=28.6343612334802, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564448, Length=437, Percent_Identity=25.629290617849, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323330, Length=234, Percent_Identity=28.6324786324786, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859893, Length=537, Percent_Identity=29.2364990689013, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI45551474, Length=555, Percent_Identity=28.2882882882883, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24642670, Length=555, Percent_Identity=28.4684684684685, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24642666, Length=555, Percent_Identity=28.4684684684685, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI161077878, Length=555, Percent_Identity=28.8288288288288, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI161077880, Length=555, Percent_Identity=28.2882882882883, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI161077496, Length=522, Percent_Identity=26.8199233716475, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI18859741, Length=576, Percent_Identity=25.1736111111111, Blast_Score=115, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 65083; Mature: 64951

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIRPRPFRSRAGAIAAAFFAVAAAGCANAPGPGAQNAAAPASAASTPPAAPSAEAPA
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAELSSWVDKPGWTAQRDMIAAAHPLAAQAGQAMLKAGGTAVDAAIAAQMVLMLVEPQA
CHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
SGIGGGAFLLHANGKTIEAYDGRETAPAAATDRLFLDANGKPLPRAALGARTVGAPGALR
CCCCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCHHHH
MLELAHRAHGKLPWRRLFQPAIRLAEQGFPLGPRLAAALANEPSLARDPAARAYFYDRNG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHEEEECCCC
APKPAGTTLKNPQLAATLRLVAAHGANAFYTGAIARDIVATVRQAPNPGVLSMQDLAQYR
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AKTREPLCADYRKWTVCGMPPPSAGGLVVAQILGLLEAQPDWRQIGAQKPVRNAVGVEPT
HHCCCCHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCHHHHCCCCCC
PFAAHLFSEAGRLAYADRAQYVADPDFVAPPGGSWKRLVERRYVAERARLIGDASAGEAS
CHHHHHHHHCCCEEEHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGSPSGLPPATAADRGAEPPSGSQITVVDRYGNAVSMASTLDERFGSRLMVRGFLLNSQL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEHHHHHHCCHH
LDFSPASAEHGKPVANRVQPGKRARSTLAPELVFEKGSSRLMMALGSAGGASTANDVAKT
CCCCCCCCCCCCCHHHHCCCCHHHHHHHCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHH
LVGMIDWGMTMQQAIALPNFGSRNGPTELEQGRVSDALAGALKARGHDVRVVELGSSLQG
HHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEECCCHHHH
IQRINVEGQSVWFGGSDPRRDGIVAGD
HHEECCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TDRIRPRPFRSRAGAIAAAFFAVAAAGCANAPGPGAQNAAAPASAASTPPAAPSAEAPA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAELSSWVDKPGWTAQRDMIAAAHPLAAQAGQAMLKAGGTAVDAAIAAQMVLMLVEPQA
CHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
SGIGGGAFLLHANGKTIEAYDGRETAPAAATDRLFLDANGKPLPRAALGARTVGAPGALR
CCCCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCHHHH
MLELAHRAHGKLPWRRLFQPAIRLAEQGFPLGPRLAAALANEPSLARDPAARAYFYDRNG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHEEEECCCC
APKPAGTTLKNPQLAATLRLVAAHGANAFYTGAIARDIVATVRQAPNPGVLSMQDLAQYR
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AKTREPLCADYRKWTVCGMPPPSAGGLVVAQILGLLEAQPDWRQIGAQKPVRNAVGVEPT
HHCCCCHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCHHHHCCCCCC
PFAAHLFSEAGRLAYADRAQYVADPDFVAPPGGSWKRLVERRYVAERARLIGDASAGEAS
CHHHHHHHHCCCEEEHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGSPSGLPPATAADRGAEPPSGSQITVVDRYGNAVSMASTLDERFGSRLMVRGFLLNSQL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEHHHHHHCCHH
LDFSPASAEHGKPVANRVQPGKRARSTLAPELVFEKGSSRLMMALGSAGGASTANDVAKT
CCCCCCCCCCCCCHHHHCCCCHHHHHHHCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHH
LVGMIDWGMTMQQAIALPNFGSRNGPTELEQGRVSDALAGALKARGHDVRVVELGSSLQG
HHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEECCCHHHH
IQRINVEGQSVWFGGSDPRRDGIVAGD
HHEECCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA