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The map label for this gene is coaX

Identifier: 53718037

GI number: 53718037

Start: 430475

End: 431254

Strand: Reverse

Name: coaX

Synonym: BPSL0397

Alternate gene names: 53718037

Gene position: 431254-430475 (Counterclockwise)

Preceding gene: 53718038

Following gene: 53718036

Centisome position: 10.58

GC content: 72.82

Gene sequence:

>780_bases
ATGAGCGGCATGTGCTTGCTGATCGACGCGGGCAACAGCCGCATCAAATGGGCGCTCGCGGACACCGCGCGCCATTTCGT
CACGAGCGGCGCGTTCGAGCATGCGAGCGACGCACCCGACTGGTCGACGCTGCCCGCGCCGCGCGGCGCGTGGATCTCGA
ACGTCGCGGGAGACGCGGCGGCCGCGCGCATCGACGCGCTGATCGAAGCGCGCTGGCCCGCGCTGCCGCGCACCGTCGTG
CGCGCGAGCGCCGCGCAATGCGGCGTGACGAACGGCTACGCGGAACCTGCGCGCCTCGGCAGCGACCGCTGGGCGGGGCT
CATCGGCGCGCACGCCGCGTTTGCGGACGAACACCTGCTGATCGCGACGTTCGGCACCGCGACGACACTCGAGGCGCTGC
GCGCGGACGGCCACTTCGCGGGCGGGCTGATCGCGCCCGGCTGGGCGCTGATGATGCGCTCGCTCGGCATGCACACCGCG
CAGTTGCCGACGGTGTCGATCGACGCGGCGACGAACCTGCTCGACGAACTCGCCGAGAACGACGCACATGCGCCGTTCGC
GATCGACACGCCGCATGCGCTGTCGGCCGGCTGCCTGCAGGCGCAGGCGGGGCTCATCGAGCGCGCATGGCGCGATCTCG
AGAAAGCCTGGCAGGCGCCCGTGCGGCTCGTGCTGTCGGGCGGCGCGGCGGATGCGATCGTGCGCGCGCTGACCGTCCCG
CACACGCGGCACGACACGCTCGTGCTGACGGGCCTCGCGCTGATCGCGCATTCGGCGTGA

Upstream 100 bases:

>100_bases
TCGGCATCGACGAAACCGGGCAGTTGCTGCTCGACACGCCCGCCGGCAGGCAGGCGATCGCGGCGGGCGACGTGTCGCTG
CGCACGCCGGGGGCCGCCCG

Downstream 100 bases:

>100_bases
CGCGCGGCGCACGCGCAGGCGGCTCGCGCGCCGCGCGCGCAAGACGCGACGCCGCGCGAAACCGCGCGGCGGATTGACGG
TAACGAAACGATTCCTGGGA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSGMCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAAAARIDALIEARWPALPRTVV
RASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLLIATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTA
QLPTVSIDAATNLLDELAENDAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVP
HTRHDTLVLTGLALIAHSA

Sequences:

>Translated_259_residues
MSGMCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAAAARIDALIEARWPALPRTVV
RASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLLIATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTA
QLPTVSIDAATNLLDELAENDAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVP
HTRHDTLVLTGLALIAHSA
>Mature_258_residues
SGMCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAAAARIDALIEARWPALPRTVVR
ASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLLIATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTAQ
LPTVSIDAATNLLDELAENDAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVPH
TRHDTLVLTGLALIAHSA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_BURPS (Q63XZ2)

Other databases:

- EMBL:   BX571965
- RefSeq:   YP_107023.1
- ProteinModelPortal:   Q63XZ2
- SMR:   Q63XZ2
- GeneID:   3092276
- GenomeReviews:   BX571965_GR
- KEGG:   bps:BPSL0397
- HOGENOM:   HBG634537
- OMA:   RTTIRSR
- ProtClustDB:   PRK13328
- BioCyc:   BPSE272560:BPSL0397-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27078; Mature: 26947

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: ACT_SITE 102-102 BINDING 93-93 BINDING 126-126 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGMCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAA
CCCEEEEEECCCCEEEEEHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCHHHHHCCHHH
AARIDALIEARWPALPRTVVRASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLL
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEE
IATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTAQLPTVSIDAATNLLDELAEN
EEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHHCC
DAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVP
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHCC
HTRHDTLVLTGLALIAHSA
CCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGMCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAA
CCEEEEEECCCCEEEEEHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCHHHHHCCHHH
AARIDALIEARWPALPRTVVRASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLL
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEE
IATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTAQLPTVSIDAATNLLDELAEN
EEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHHCC
DAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVP
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHCC
HTRHDTLVLTGLALIAHSA
CCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA