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The map label for this gene is gylR [H]

Identifier: 53718029

GI number: 53718029

Start: 422575

End: 423438

Strand: Reverse

Name: gylR [H]

Synonym: BPSL0389

Alternate gene names: 53718029

Gene position: 423438-422575 (Counterclockwise)

Preceding gene: 53718036

Following gene: 53718028

Centisome position: 10.39

GC content: 71.53

Gene sequence:

>864_bases
GTGAACAAGTCCGCCTCGCCCCCCTCCGACGCCCCCGACGACGACCTCGCCGACGATCATGACACCGGCGAGGAAAAAGT
CCGCTCCGGCATCCAGTCGATCGAGGTCGGCTTTCGCCTGCTCGACGTGCTGACGGGCGAGCCGCGCGCGATGATGCTGC
GCGACCTCGCGCAGCGCGCGGCGATGAGCCCGGCGAAGGCGCACCGCTACCTCGTCAGTTTCCAGCGGCTCGGGCTCGTG
TCGCAGGATCCGGTGTCGGGCCGCTACGAGCTCGGCGGCTTCGCGTTGCAGATGGGCCTGGCGCGCCTCGCGCGCGTCGA
CGGCGTGAAGCTCGCGCGCATCGCGCTCACCGCGCTGCGCGATCAGCTCGACCAGACGGTCGGCATCGCGGTATGGGGCA
ACCAGGGGCCGACGATCGTCCACTGGATGGAGTCGAGCCATCCGGCGAAGGCGTCGCTCAAGCTCGGCGACGTGATGCCG
CTCCTCGGCTCGGCGACGGGCCTCGTGTTCGCCGCGTACCTGCCGCGCGGCAAGACGGCCGCGATGATCGAGCGCGAGCT
CGCCGACACGCGGCGCGCCGCGCACTATACCGGCCCGCGCACGCGCGCCGAAGTCGACGCGGTGCTCGCCGACGTGCGCG
CGCATCGCGCGGCGCGCGTCGAAGGCATGCTGCTGCCGACGATCAACGCATTCGGGATGCCGGTGTTCGACGCGGTCGGC
GAGCTCGCGCTCGCGATCATCGCGCTCGGCCACGAGGGCGCGTTCGACATCCGCTGGGGCGGCGAGGTCGACACCGCGCT
GCGCACCTGCGCGCAGAAGCTGTCGTACGAGCTTGGGTATAGTGAGGGAGCGCGCGACGCCTGA

Upstream 100 bases:

>100_bases
AGCCGTTGTAGTGACGATGGAAGGAATCTATTTTACGATGGTGAATCCGCACGGCGGCCCGCGCCGCGAGCCGCCCCCTC
CCCATTCTTCCCGCCACGCC

Downstream 100 bases:

>100_bases
CGGGCGCCGCCGCATCCCGGGCCGCGCGAATCGCGCGCGCCCCGTTTCGTCGCCGTTCGAGAGGCCCGCCCGCCGCTGAT
GCCGTTGTCGTCCATCGTTT

Product: IclR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNKSASPPSDAPDDDLADDHDTGEEKVRSGIQSIEVGFRLLDVLTGEPRAMMLRDLAQRAAMSPAKAHRYLVSFQRLGLV
SQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTALRDQLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMP
LLGSATGLVFAAYLPRGKTAAMIERELADTRRAAHYTGPRTRAEVDAVLADVRAHRAARVEGMLLPTINAFGMPVFDAVG
ELALAIIALGHEGAFDIRWGGEVDTALRTCAQKLSYELGYSEGARDA

Sequences:

>Translated_287_residues
MNKSASPPSDAPDDDLADDHDTGEEKVRSGIQSIEVGFRLLDVLTGEPRAMMLRDLAQRAAMSPAKAHRYLVSFQRLGLV
SQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTALRDQLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMP
LLGSATGLVFAAYLPRGKTAAMIERELADTRRAAHYTGPRTRAEVDAVLADVRAHRAARVEGMLLPTINAFGMPVFDAVG
ELALAIIALGHEGAFDIRWGGEVDTALRTCAQKLSYELGYSEGARDA
>Mature_287_residues
MNKSASPPSDAPDDDLADDHDTGEEKVRSGIQSIEVGFRLLDVLTGEPRAMMLRDLAQRAAMSPAKAHRYLVSFQRLGLV
SQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTALRDQLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMP
LLGSATGLVFAAYLPRGKTAAMIERELADTRRAAHYTGPRTRAEVDAVLADVRAHRAARVEGMLLPTINAFGMPVFDAVG
ELALAIIALGHEGAFDIRWGGEVDTALRTCAQKLSYELGYSEGARDA

Specific function: May be an activator protein for the gylABX operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=279, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788131, Length=256, Percent_Identity=25, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30842; Mature: 30842

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSASPPSDAPDDDLADDHDTGEEKVRSGIQSIEVGFRLLDVLTGEPRAMMLRDLAQRA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AMSPAKAHRYLVSFQRLGLVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTALR
HCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DQLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLVFAAYLPRGKTA
HHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHCHHHHHHHHHCCCCCHH
AMIERELADTRRAAHYTGPRTRAEVDAVLADVRAHRAARVEGMLLPTINAFGMPVFDAVG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHCCCHHHHHHH
ELALAIIALGHEGAFDIRWGGEVDTALRTCAQKLSYELGYSEGARDA
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNKSASPPSDAPDDDLADDHDTGEEKVRSGIQSIEVGFRLLDVLTGEPRAMMLRDLAQRA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AMSPAKAHRYLVSFQRLGLVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTALR
HCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DQLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLVFAAYLPRGKTA
HHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHCHHHHHHHHHCCCCCHH
AMIERELADTRRAAHYTGPRTRAEVDAVLADVRAHRAARVEGMLLPTINAFGMPVFDAVG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHCCCHHHHHHH
ELALAIIALGHEGAFDIRWGGEVDTALRTCAQKLSYELGYSEGARDA
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3225846; 12000953 [H]