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The map label for this gene is can [H]

Identifier: 53718012

GI number: 53718012

Start: 401445

End: 402215

Strand: Reverse

Name: can [H]

Synonym: BPSL0372

Alternate gene names: 53718012

Gene position: 402215-401445 (Counterclockwise)

Preceding gene: 53718013

Following gene: 53718011

Centisome position: 9.87

GC content: 66.15

Gene sequence:

>771_bases
ATGAACAAGAACGACCATCCGCTCTCCCATCTGTTCGACAACAACGACGCCTGGGTCAAGCGCAAGCTCGCCGACGACCC
GCAATACTTCTCGCGCCTCGCCGATCAGCAGGCGCCCGAATATCTCTGGATCGGCTGCTCCGATTCGCGCGTGCCCGCGA
ACCAGATCATCGGCCTGCCGCCGGGCGAAGTGTTCGTCCATCGCAACATCGCGAACGTCGTCGTGCACACCGATCTGAAC
TGCCTGTCGGTGATCCAGTTCGCGGTCGACCTGCTGAAGGTCAAGCACGTCATGGTCGTCGGCCACTACGGCTGCTCGGG
CGTGAACGCGGCGCTGCACAACCGCCGCGTCGGGCTCGCGGACAACTGGCTGCACCACGTGCAGGACGTGCGCGAAAAGC
ACGCGGCGCTGCTCGAGGACTGGCCGCTCGGCGAAGCGCGCTACCGGCGGCTGATCGAGCTCAACGCGATCGAGCAGGTG
GTCAACGTGTGCCGCACGACGATCGTCAACGACGCGTGGGCGCGCGGCCAGCCGCTTACCGTGCACGCGCTCGTGTACGG
CGTGCACGACGGCCGGATGCGCAATCTCGGGATGGCCGTGTCGCATGCCGAGCAGCTCGATGCGACGTACCGCCGCGCGG
TCGCCGCGCTTTCGGCAAGCGGCGCGCATTCGGCGGACAATGACGTCGTGGCGGCCGACGCGGCGCAACTCGCCGGCGCG
GTCGATCTCATTGCCCAAACCATCAAGGAGACGAAACATGACGGCTGTTGA

Upstream 100 bases:

>100_bases
GCCGGGCGACGCGGCCGACGGCGGCAAGCTCGCCGCCGCGTGAGCCGCGCCCGCCCCGCGCTCGAACGCCCCTTTTTTCA
TCCCACTGAACCGACTTGAG

Downstream 100 bases:

>100_bases
TCAGGATCCGATCGTCATCGCATCGGCGGCGCGCACGCCGATCGCGGGCTTTCAGGGCGAGTTCGCGTCGCTCGCCGCGC
CGCAGCTGGGCGCGGCCGCG

Product: putative carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNKNDHPLSHLFDNNDAWVKRKLADDPQYFSRLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHTDLN
CLSVIQFAVDLLKVKHVMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVREKHAALLEDWPLGEARYRRLIELNAIEQV
VNVCRTTIVNDAWARGQPLTVHALVYGVHDGRMRNLGMAVSHAEQLDATYRRAVAALSASGAHSADNDVVAADAAQLAGA
VDLIAQTIKETKHDGC

Sequences:

>Translated_256_residues
MNKNDHPLSHLFDNNDAWVKRKLADDPQYFSRLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHTDLN
CLSVIQFAVDLLKVKHVMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVREKHAALLEDWPLGEARYRRLIELNAIEQV
VNVCRTTIVNDAWARGQPLTVHALVYGVHDGRMRNLGMAVSHAEQLDATYRRAVAALSASGAHSADNDVVAADAAQLAGA
VDLIAQTIKETKHDGC
>Mature_256_residues
MNKNDHPLSHLFDNNDAWVKRKLADDPQYFSRLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHTDLN
CLSVIQFAVDLLKVKHVMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVREKHAALLEDWPLGEARYRRLIELNAIEQV
VNVCRTTIVNDAWARGQPLTVHALVYGVHDGRMRNLGMAVSHAEQLDATYRRAVAALSASGAHSADNDVVAADAAQLAGA
VDLIAQTIKETKHDGC

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=50.4716981132076, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786534, Length=205, Percent_Identity=26.3414634146341, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324292, Length=191, Percent_Identity=29.3193717277487, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 28230; Mature: 28230

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNDHPLSHLFDNNDAWVKRKLADDPQYFSRLADQQAPEYLWIGCSDSRVPANQIIGLP
CCCCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHEECCC
PGEVFVHRNIANVVVHTDLNCLSVIQFAVDLLKVKHVMVVGHYGCSGVNAALHNRRVGLA
CCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCCCH
DNWLHHVQDVREKHAALLEDWPLGEARYRRLIELNAIEQVVNVCRTTIVNDAWARGQPLT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEE
VHALVYGVHDGRMRNLGMAVSHAEQLDATYRRAVAALSASGAHSADNDVVAADAAQLAGA
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHH
VDLIAQTIKETKHDGC
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNKNDHPLSHLFDNNDAWVKRKLADDPQYFSRLADQQAPEYLWIGCSDSRVPANQIIGLP
CCCCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHEECCC
PGEVFVHRNIANVVVHTDLNCLSVIQFAVDLLKVKHVMVVGHYGCSGVNAALHNRRVGLA
CCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCCCH
DNWLHHVQDVREKHAALLEDWPLGEARYRRLIELNAIEQVVNVCRTTIVNDAWARGQPLT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEE
VHALVYGVHDGRMRNLGMAVSHAEQLDATYRRAVAALSASGAHSADNDVVAADAAQLAGA
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHH
VDLIAQTIKETKHDGC
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]