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The map label for this gene is csgA [H]

Identifier: 53718010

GI number: 53718010

Start: 399557

End: 400234

Strand: Reverse

Name: csgA [H]

Synonym: BPSL0370

Alternate gene names: 53718010

Gene position: 400234-399557 (Counterclockwise)

Preceding gene: 53718011

Following gene: 53718009

Centisome position: 9.82

GC content: 73.45

Gene sequence:

>678_bases
ATGAAGACCGTATTGATCGTCGGCGCATCGCGCGGCATCGGCCGCGAATTCGTCGGCCAGTATCTGCATGACGGCTGGCG
CGTGATCGCCACGGCGCGCGACGCCGCGGCGCTCGCGGCGCTCGATGCGCTCGGCGCGCGCGCGCTCGCGCTCGACGTCG
CGCAGCCCGACGACATCGCGGCGTTCGACGCGCGCCTCGGCGGCGCCGCGCTCGACGCGGCCGTCGTCGTGTCGGGCGTG
TACGGCCCGCGCACGGCGGGCGTCGAGCCCATCGGCGTGGAGGACTTCGATGCGGTGATGCACACGAACGTGCTCGGCCC
GATGCTGCTGATGCCGATCCTGCTGCCGCGCGTCGAGGCGAGCCGCGGCGTCCTCGCGGTGCTGTCGAGCAAGATGGGCA
GCATCGGCGAGGCGACCGGCACGACCGGCTGGCTCTATCGCGCGAGCAAGGCGGCGGTGAACGACGCGCTCAGGATCGCT
TCGCTGCAGGCGCGGCACGCGGCCTGCATCGCGCTGCATCCGGGCTGGGTGCGCACCGACATGGGCGGCGCGCAGGCGGC
GCTCGATCCGCAGGCGAGCGTCGCCGGCATGCGCCGCGTGATCGCGCAGGCGGCGGGCGACCGCGAGCGCGCGAACGGTC
GCTTCTTCCAATACGATGGCGTCGAGCTCGGCTGGTGA

Upstream 100 bases:

>100_bases
CAAGCGCGGCGTGGCGAGCCTGTGCATCGGCGGCGGCGAAGCGACCGCGATGGGCATCGAGCTGATCTGACCTGAGCGCG
CATCGAACGGGAGCCCTCCG

Downstream 100 bases:

>100_bases
GCCGGCGCGCCGCCGCATTCCTCCGATCACGATGCAACCCACGACGAACGCCCCCGAGCGCCCCCTCGACTGCCCGTGCG
GCGGCGCCGCGCCCGGCGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGIGREFVGQYLHDGWRVIATARDAAALAALDALGARALALDVAQPDDIAAFDARLGGAALDAAVVVSGV
YGPRTAGVEPIGVEDFDAVMHTNVLGPMLLMPILLPRVEASRGVLAVLSSKMGSIGEATGTTGWLYRASKAAVNDALRIA
SLQARHAACIALHPGWVRTDMGGAQAALDPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW

Sequences:

>Translated_225_residues
MKTVLIVGASRGIGREFVGQYLHDGWRVIATARDAAALAALDALGARALALDVAQPDDIAAFDARLGGAALDAAVVVSGV
YGPRTAGVEPIGVEDFDAVMHTNVLGPMLLMPILLPRVEASRGVLAVLSSKMGSIGEATGTTGWLYRASKAAVNDALRIA
SLQARHAACIALHPGWVRTDMGGAQAALDPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW
>Mature_225_residues
MKTVLIVGASRGIGREFVGQYLHDGWRVIATARDAAALAALDALGARALALDVAQPDDIAAFDARLGGAALDAAVVVSGV
YGPRTAGVEPIGVEDFDAVMHTNVLGPMLLMPILLPRVEASRGVLAVLSSKMGSIGEATGTTGWLYRASKAAVNDALRIA
SLQARHAACIALHPGWVRTDMGGAQAALDPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=30.5785123966942, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193207563, Length=246, Percent_Identity=29.2682926829268, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558990, Length=244, Percent_Identity=29.9180327868852, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558996, Length=246, Percent_Identity=27.6422764227642, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558992, Length=243, Percent_Identity=30.0411522633745, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=28.2868525896414, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23399; Mature: 23399

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGIGREFVGQYLHDGWRVIATARDAAALAALDALGARALALDVAQPDDIA
CCEEEEEECCCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCHH
AFDARLGGAALDAAVVVSGVYGPRTAGVEPIGVEDFDAVMHTNVLGPMLLMPILLPRVEA
HHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SRGVLAVLSSKMGSIGEATGTTGWLYRASKAAVNDALRIASLQARHAACIALHPGWVRTD
CCCHHHHHHHHCCCCCCCCCCCHHEEECHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAALDPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCEEEECCEEECC
>Mature Secondary Structure
MKTVLIVGASRGIGREFVGQYLHDGWRVIATARDAAALAALDALGARALALDVAQPDDIA
CCEEEEEECCCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCHH
AFDARLGGAALDAAVVVSGVYGPRTAGVEPIGVEDFDAVMHTNVLGPMLLMPILLPRVEA
HHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SRGVLAVLSSKMGSIGEATGTTGWLYRASKAAVNDALRIASLQARHAACIALHPGWVRTD
CCCHHHHHHHHCCCCCCCCCCCHHEEECHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAALDPQASVAGMRRVIAQAAGDRERANGRFFQYDGVELGW
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]