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The map label for this gene is glmS1 [H]

Identifier: 53717953

GI number: 53717953

Start: 331614

End: 333446

Strand: Reverse

Name: glmS1 [H]

Synonym: BPSL0312

Alternate gene names: 53717953

Gene position: 333446-331614 (Counterclockwise)

Preceding gene: 53717954

Following gene: 53717943

Centisome position: 8.18

GC content: 67.7

Gene sequence:

>1833_bases
ATGTGCGGGATTGTCGGCGCAGTTGCGCAACGTAACATCGTTCCGGTGCTGATCGAAGGGCTGCGCCGTCTCGAGTATCG
CGGCTACGACTCATGCGGCGTCGCGGTACTCGACGCCGGCGCCCCCGCGCCGGGCACGCCCAAGCGCGCGCGCAGCGTCG
CGCGGGTGGCCGATCTCGACGCGCAGGTGCGCGAATCGCATCTCGAAGGCGAGACGGGCATCGCGCACACGCGCTGGGCG
ACGCACGGCGCGCCCGTCACGCACAACGCGCATCCGATCTTCTCGTCGGACGCGCTCGCGCTCGTGCACAACGGCATCAT
CGAGAACTTCGAGCCGCTGCGCGAAGCGCTGCGCGCGAAGGGTTACGCATTCGTGTCGCAGACCGACACCGAGGTCATCG
CTCACCTGATCCACAGCCTCTATCGCGGCAACCTGTTCGCGGCCGTTCAGCAAGCCGTCAAGCAACTGCACGGCGCCTAC
GCGATCGCGGTGACCCACAAGGACGAGCCGCATACCGTCGTCGGGGCGCGCCAGGGCTCGCCGCTCGTCGTCGGTTTCGG
CGAGCGCGAGAATTTCCTCGCGTCCGACGCGCTCGCGCTCGCCGGCAGCACCGATCGCTTCACGTTCCTCGAGGAAGGCG
ACGTCTGCGAGCTCACGCTCGAGGGCGTGACTGTCGTCGATCGCGACGGCGCGCGCGCCGCGCGCGACGTGCGCGTCGTC
GCCGCATACGGCGGCGCGGTCGAGCTCGGCCCGTACCGGCATTTCATGCAGAAGGAGATCTTCGAGCAGCCGCGCGCGAT
CGCCGACACGATTGCGCAAACGGACGCGTTCGATCCGCCGCTGTTCGGCGAGCGCGCGAGCAGCGTGTTCGCGGGCATCG
ACAGCCTGCTGATCCTCGCATGCGGCACGAGCTACTACTCGGGCCTCACCGCGAAATACTGGCTCGAATCGATCGCGAAG
ATCCCGACGCAGGTCGAGATCGCGAGCGAATACCGCTACCGCGAATCGGTGCCGAACCCGCGCGCGCTCGTCGTCGTGAT
CTCGCAATCGGGCGAGACGGCCGATACGCTCGCCGCGCTCAAGCACGCGCAGGCGCTCGGCCATGCGCACACGCTCGCAA
TCTGCAACGTCGCGACGAGCGCGATGGTGCGCCAGACCGAGCTGCAATTCCTCACGCACGCGGGCACCGAGATCGGCGTC
GCGTCGACGAAGGCGTTCACGACGCAGCTCGTCGCGCTGTTCGTACTCGCGGCGACGCTCGGCAAGCTGCGCGGCCACGT
CGATGCGGCTCGCGAAGCCGATTACCTGAAGCAACTGCGCCACCTGCCCGCCGCGCTCAACAGCGTGCTCGCGCTCGAGC
CGCAGATCATCGCTTGGTCCGACGAGTTCGCGCGCAAGGAAAACGCGCTGTTCCTCGGCCGCGGGCTGCACTATCCGATC
TCGCTCGAAGGCGCGCTGAAGCTCAAGGAGATCTCGTACATCCACGCGGAAGCGTACCCGGCGGGCGAACTGAAGCACGG
GCCGCTCGCGCTCGTGACGGAGGCGATGCCGGTCGTGACGGTCGCGCCGAACGACACGCTGCTCGAGAAGCTGAAGTCGA
ACATGCAGGAGGTGCGCGCGCGCGGCGGCGAACTGTACGTGTTCGCCGACGCGGACACGCACATCGTCAACGACGAAGGG
CTGCACGTGATCCGCATGCCCGAGCATTACGGGCCGCTGTCGCCGATCCTGCACGTCGTGCCGCTGCAACTGCTCGCGTA
TCACACCGCCTGCGCACGCGGCACCGATGTCGACAAGCCGCGCAATCTCGCGAAATCGGTGACGGTGGAATAA

Upstream 100 bases:

>100_bases
GAGCGGCTACGTGCGCCCCGTCAAGAAGAAGAGCTGAACCGTTTTTCGGGCGCGCAGCGGCGCGCCTGCATCATTGTCGA
GTTTCGAAGGATAGATTTTC

Downstream 100 bases:

>100_bases
ACGCGCACGACCGAACGGGCGATTCGCGGCGCGACGTCGCGGATCGCCCGCCTGCCGCGCCGGCCGTTTTCCCCTCAAGT
CTTCACGAATATATCGGCGC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLDAGAPAPGTPKRARSVARVADLDAQVRESHLEGETGIAHTRWA
THGAPVTHNAHPIFSSDALALVHNGIIENFEPLREALRAKGYAFVSQTDTEVIAHLIHSLYRGNLFAAVQQAVKQLHGAY
AIAVTHKDEPHTVVGARQGSPLVVGFGERENFLASDALALAGSTDRFTFLEEGDVCELTLEGVTVVDRDGARAARDVRVV
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQTDAFDPPLFGERASSVFAGIDSLLILACGTSYYSGLTAKYWLESIAK
IPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAALKHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGV
ASTKAFTTQLVALFVLAATLGKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSDEFARKENALFLGRGLHYPI
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEG
LHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_610_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLDAGAPAPGTPKRARSVARVADLDAQVRESHLEGETGIAHTRWA
THGAPVTHNAHPIFSSDALALVHNGIIENFEPLREALRAKGYAFVSQTDTEVIAHLIHSLYRGNLFAAVQQAVKQLHGAY
AIAVTHKDEPHTVVGARQGSPLVVGFGERENFLASDALALAGSTDRFTFLEEGDVCELTLEGVTVVDRDGARAARDVRVV
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQTDAFDPPLFGERASSVFAGIDSLLILACGTSYYSGLTAKYWLESIAK
IPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAALKHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGV
ASTKAFTTQLVALFVLAATLGKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSDEFARKENALFLGRGLHYPI
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEG
LHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_610_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLDAGAPAPGTPKRARSVARVADLDAQVRESHLEGETGIAHTRWA
THGAPVTHNAHPIFSSDALALVHNGIIENFEPLREALRAKGYAFVSQTDTEVIAHLIHSLYRGNLFAAVQQAVKQLHGAY
AIAVTHKDEPHTVVGARQGSPLVVGFGERENFLASDALALAGSTDRFTFLEEGDVCELTLEGVTVVDRDGARAARDVRVV
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQTDAFDPPLFGERASSVFAGIDSLLILACGTSYYSGLTAKYWLESIAK
IPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAALKHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGV
ASTKAFTTQLVALFVLAATLGKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSDEFARKENALFLGRGLHYPI
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEG
LHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=36.0058309037901, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI4826742, Length=691, Percent_Identity=34.7322720694645, Blast_Score=374, Evalue=1e-103,
Organism=Escherichia coli, GI1790167, Length=617, Percent_Identity=55.5915721231767, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI87082251, Length=316, Percent_Identity=23.1012658227848, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788651, Length=245, Percent_Identity=27.7551020408163, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=432, Percent_Identity=38.1944444444444, Blast_Score=277, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17532899, Length=442, Percent_Identity=37.3303167420815, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17532897, Length=442, Percent_Identity=37.3303167420815, Blast_Score=273, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6322745, Length=455, Percent_Identity=36.043956043956, Blast_Score=263, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=29.3981481481481, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=37.2549019607843, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6323958, Length=213, Percent_Identity=29.1079812206573, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357745, Length=691, Percent_Identity=35.3111432706223, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI28573187, Length=257, Percent_Identity=26.4591439688716, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65862; Mature: 65862

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLDAGAPAPGTPKRARSVARVADLD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
AQVRESHLEGETGIAHTRWATHGAPVTHNAHPIFSSDALALVHNGIIENFEPLREALRAK
HHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GYAFVSQTDTEVIAHLIHSLYRGNLFAAVQQAVKQLHGAYAIAVTHKDEPHTVVGARQGS
CEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCC
PLVVGFGERENFLASDALALAGSTDRFTFLEEGDVCELTLEGVTVVDRDGARAARDVRVV
CEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCCHHHCEEEE
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQTDAFDPPLFGERASSVFAGIDSLLILA
EEECCEEEECHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
CGTSYYSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAAL
HCCHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHH
KHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGVASTKAFTTQLVALFVLAATL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSDEFARKENALFLGRGLHYPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCCCEEEECCCCCCE
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRA
ECCCCEEEEHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGELYVFADADTHIVNDEGLHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKP
CCCEEEEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
RNLAKSVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLDAGAPAPGTPKRARSVARVADLD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
AQVRESHLEGETGIAHTRWATHGAPVTHNAHPIFSSDALALVHNGIIENFEPLREALRAK
HHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GYAFVSQTDTEVIAHLIHSLYRGNLFAAVQQAVKQLHGAYAIAVTHKDEPHTVVGARQGS
CEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCC
PLVVGFGERENFLASDALALAGSTDRFTFLEEGDVCELTLEGVTVVDRDGARAARDVRVV
CEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCCHHHCEEEE
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQTDAFDPPLFGERASSVFAGIDSLLILA
EEECCEEEECHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
CGTSYYSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAAL
HCCHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHH
KHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGVASTKAFTTQLVALFVLAATL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSDEFARKENALFLGRGLHYPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCCCEEEECCCCCCE
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRA
ECCCCEEEEHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGELYVFADADTHIVNDEGLHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKP
CCCEEEEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
RNLAKSVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]