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The map label for this gene is kdsB

Identifier: 161723207

GI number: 161723207

Start: 1016279

End: 1017070

Strand: Reverse

Name: kdsB

Synonym: BPSL0876

Alternate gene names: 161723207

Gene position: 1017070-1016279 (Counterclockwise)

Preceding gene: 53718516

Following gene: 53718514

Centisome position: 24.96

GC content: 70.71

Gene sequence:

>792_bases
ATGACCTCCCCGCTCCCTTTCGTCGCCGTCGTCCCCGCCCGCCTCGCGTCGACCCGCCTGCCGAACAAGCCGCTCGCCGA
TCTCGGCGGCAAGCCGATGGTCGTGCGCGTCGCCGAGCGCGCGCGTGAAGCCGGCGCGCAGCAGGTGCTCGTCGCATCCG
ACGCGCAGCGCGTGCTCGACGCGGTGCGCGAGCACGGCTTCGACGCGGTGCTCACGCGCGCCGACCATCCGTCCGGCACC
GATCGCCTCGCCGAGGTCGCCGCGAAGCTCGGCTTCGACGACGACACGATCGTCGTCAACGTCCAGGGCGACGAGCCGCT
GATCGATCCGCAGCTCGTGCGCGACGTAGCGTCGCACCTCGCCGCGCACCCGTCGTGCGCGATCGCGACGGCCGCGCACC
CGATTCACGAAGCGCACGAGGTGTTCAATCCGAACTACGTGAAGGTCGTGCTCGACGCGCACGGCGTCGCGCTGTACTTC
TCGCGCGCGCCGATTCCGTGGTCGCGCGATGCTTACCTGCCGCACTGGCCGAACGTCGCGGCGATGCCCGCGCCGACGTG
CCCGGTCTATCGGCACATCGGCCTGTACGCGTATCGCGCACGCTTCCTGCGCACGTATCCGACGCTCGCGCAGGCGCCGA
TCGAGGCGGCCGAACAGCTCGAGCAGTTGCGCGCGATGTGGCATGGCGAGCGGATCGCGGTGCGCGTCACCGAGCATGCG
CCCGAGGCCGGCATCGACACGCCGGCCGATCTCGAACGCGTGCAGGCCCTTTTTCGGTCTCGCGCCAAATAA

Upstream 100 bases:

>100_bases
CGCGCGCCGAACCGCCGCCGCCCGAGCACGCCACGCCGCTGCCCGCCCGCATCGCGTGCGGGCGCATTTTTCGAACTCCT
TTGCGCTTCGCGCCCGTCCG

Downstream 100 bases:

>100_bases
CCCATGGCATAATCGGGCGATTGCGCGAGCGATCCGCCCGCGCCGCTCACCGAGATTCGCCCCAAGCCCGACCTCCGCCG
GCCGCCGCGCGTCGCTTCCG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGT
DRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYF
SRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHA
PEAGIDTPADLERVQALFRSRAK

Sequences:

>Translated_263_residues
MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGT
DRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYF
SRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHA
PEAGIDTPADLERVQALFRSRAK
>Mature_262_residues
TSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGTD
RLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFS
RAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHAP
EAGIDTPADLERVQALFRSRAK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=255, Percent_Identity=53.3333333333333, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_BURM7 (A3MN47)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001081683.1
- ProteinModelPortal:   A3MN47
- SMR:   A3MN47
- GeneID:   4892530
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_2153
- TIGR:   BMA10247_2153
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- ProtClustDB:   PRK05450
- BioCyc:   BMAL320389:BMA10247_2153-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28758; Mature: 28627

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLD
CCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCEEHHHHHHHHHCCHHEEEHHHHHHHHHH
AVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHL
HHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
AAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVA
HCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCC
AMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PEAGIDTPADLERVQALFRSRAK
CCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLD
CCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCEEHHHHHHHHHCCHHEEEHHHHHHHHHH
AVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHL
HHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
AAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVA
HCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCC
AMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PEAGIDTPADLERVQALFRSRAK
CCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA