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The map label for this gene is pheS [H]

Identifier: 161723202

GI number: 161723202

Start: 2312221

End: 2313243

Strand: Reverse

Name: pheS [H]

Synonym: BPSL1941

Alternate gene names: 161723202

Gene position: 2313243-2312221 (Counterclockwise)

Preceding gene: 53719555

Following gene: 53719553

Centisome position: 56.77

GC content: 63.83

Gene sequence:

>1023_bases
ATGGGATCAATGGATCTGGACCAGATTGTCGCCGACGCGCAGCAGTCGTTCGAAGGGGCTGCGGATATCACCACGCTCGA
GAACGAGAAGGCGCGGTTTCTCGGTAAGTCGGGCGCGCTGACCGAGCTGCTGAAGGGCCTCGGCAAGCTCGATCCCGAGA
CGCGCAAGACGGAAGGCGCGCGCATCAATGTCGCGAAGCAGCAGGTCGAAGCCGCGCTCAACGCGCGCCGCCAGGCGCTT
GCCGACGCGCTCCTGAACCAGCGTCTCGCCGCCGAGGCGATCGACGTCACGCTGCCCGGCCGAGGTGCCGGGGCGGGAAG
CCTCCATCCGGTGATGCGCACGTGGGAGCGTGTCGAACAGATTTTTCGCTCGATCGGTTTCGACGTGGCCGACGGCCCCG
AGATCGAAACCGACTGGTACAACTTCACCGCATTGAACAGCCCGGAGAATCATCCGGCGCGCTCGATGCAGGATACGTTC
TACGTCGACGGCAAGGACGCGGACGGCCGCCCGCTGCTGCTGCGCACGCACACGAGCCCGATGCAGGTCCGCTATGCGCG
AATGAACCGGCCGCCCATCAAGGTGATCGCGCCGGGCCGCACGTACCGCGTCGACAGCGATGCGACGCACTCGCCGATGT
TCAACCAGGTCGAAGGCTTGTGGATCGACGAGAACGTCAGCTTCGCGGACCTGAAGGGCGCTTATACGGATTTCCTGAAG
AAATTCTTCGAGCGCGACGACATTCTCGTGCGCTTCCGTCCGTCGTATTTCCCGTTCACCGAGCCGTCGGCCGAGATCGA
CATGATGTTCGAGCACGGCAAGAACGCCGGCAAGTGGCTCGAGATTTCCGGTTCCGGCCAGGTGCATCCGACCGTGATCC
GCAACATGGGGCTCGATCCCGAGCGCTATATCGGTTTCGCGTTCGGCAGCGGCCTCGAGCGGCTGACGATGCTGCGCTAC
GGCGTGCAGGATCTGCGCCTGTTCTTCGAGAACGATCTGCGCTTCCTGCGGCAGTTCGCGTAA

Upstream 100 bases:

>100_bases
CCGGTAGTCGCGGCCGCTGCAGCGAAAACGGGGCTCTTCCGAGCCCCTTTTTTGTTGGGTCGGGCGTTTCGCTCGACGAG
CACAACGGACGTTGGAAGTG

Downstream 100 bases:

>100_bases
CGGCGCGACCGTCCCGCTCCGCGCCCGGCCGGCCCGTCGAGGCGGCGCGCCGGGCCTCGATCTAATCTGTTTCGAACGTG
GATATCCATGCAATTCCCTG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARRQAL
ADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTF
YVDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGAYTDFLK
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRY
GVQDLRLFFENDLRFLRQFA

Sequences:

>Translated_340_residues
MGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARRQAL
ADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTF
YVDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGAYTDFLK
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRY
GVQDLRLFFENDLRFLRQFA
>Mature_339_residues
GSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARRQALA
DALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTFY
VDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGAYTDFLKK
FFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRYG
VQDLRLFFENDLRFLRQFA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=263, Percent_Identity=31.9391634980989, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI5729820, Length=290, Percent_Identity=30.6896551724138, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1788007, Length=334, Percent_Identity=57.7844311377245, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17508957, Length=265, Percent_Identity=33.5849056603774, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32563657, Length=265, Percent_Identity=33.5849056603774, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32566635, Length=275, Percent_Identity=32.3636363636364, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321087, Length=267, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6325304, Length=327, Percent_Identity=26.605504587156, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18858079, Length=290, Percent_Identity=31.0344827586207, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17137424, Length=248, Percent_Identity=30.241935483871, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38272; Mature: 38141

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGA
CCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHCCCCCHHHHHHHHHCCCCCHHCCCCC
RINVAKQQVEAALNARRQALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHH
IFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTFYVDGKDADGRPLLLRTHTSP
HHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCC
MQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGAYTDFLK
HHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHH
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDP
HHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCH
ERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
HHHEEEHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSMDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGA
CCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHCCCCCHHHHHHHHHCCCCCHHCCCCC
RINVAKQQVEAALNARRQALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHH
IFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTFYVDGKDADGRPLLLRTHTSP
HHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCC
MQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGAYTDFLK
HHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHH
KFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDP
HHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCH
ERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
HHHEEEHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA