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The map label for this gene is dinB [H]

Identifier: 161723200

GI number: 161723200

Start: 2780897

End: 2782129

Strand: Reverse

Name: dinB [H]

Synonym: BPSL2306

Alternate gene names: 161723200

Gene position: 2782129-2780897 (Counterclockwise)

Preceding gene: 53719926

Following gene: 53719911

Centisome position: 68.28

GC content: 70.56

Gene sequence:

>1233_bases
TTGGACAAGCCGATGCCCCCCTCCGACCCGCCTCCGCCGCCCTCGGGCGACGCGGCGCACCTCGCGCGCAAGATCATCCA
TTGCGACTGCGACTGTTTCTACGCGTCGGTCGAGATGCGCGACGATCCGTCGCTGCGCGGCCGTCCGCTCGCGGTCGGCG
GCCGTCCCGACCAGCGCGGCGTGATCGCGACCTGCAACTACGACGCGCGCCGCTACGGCGTGCATTCGGCGATGTCGTCG
GCGCTCGCGATGCGCAAGTGTCCGGATCTGCTGATCCTGCCGCCCGCGATGGACAAGTACCGCGCGGCGTCGCGGCTCAT
CATGGCGATCTATCGCGACTACACGCCCGACGTCGAGCCGCTGTCGCTCGACGAGGCGTACCTCGACGTGAGCCGCGCGA
CGCGCTGTCAGGGCAGCGGCACGCTGATCGCGCGCGAGATTCGCGAGCGCGTGCGCGATACGGTGGGCGTCACGGTGTCG
GCGGGCGTCGCGCCGAACAAGTTCATCGCGAAGATCGCGTCCGACTGGAACAAGCCCGACGGCCTGTTCGTCGTGCGTCC
GCACGAAGTCGACGCGTTCGTCGCCGCGCTGCCCGTGCGCAAGCTGCACGGCGTCGGCAAGGTGACGGCGGCGCGTCTCG
ACAAGCTCGGCATCCGTACCTGCGCGCAATTGCGCGACTGGTCGCTGTTCGATCTGCATCGCACGTTCGGCGCGTTCGGC
AGACGGCTCCACGAGCTCGCGCGCGGCATCGACGAGCGGCCGGTGCGCGCGGACCAGGCGCGCAAGTCGGTGAGCGTCGA
GACGACCTACGTGCAGGACCTCGCGGCGCTCGACGCGTGCGCGGCCGAGATCCGGCGGCTGACCGGGCTGCTCGACGCGC
GGATCGAACGGGCGGGAGCCGCGCGCTCGATCAGGAAGCTGTACGTGAAGATCCGCTTCGCGGATTTCCAGCGCACGACG
GTCGAATGCGTCGCCGACGCGACCGATGCCGACACCGCGGTCGCGCTGCTCGCGAAAGGGCTCGCGCGCCGCAGGCAGGC
GGTGCGGCTGTTGGGCGTCGGCGTGCGGATCGACGAGGACACGGCCGAGCGGCACGGACAGATCGCGCTCTTCGACGACG
AGGACATGAGCGACGAAAGTGCCGAAGGCGACGAAGGCGGTGAAGTCGGCGAGGGCGGTGAGGGCGGCGAGGACGGCGAG
GGTGACGAAGGCGATGCGTCGCCCGGCGCATGA

Upstream 100 bases:

>100_bases
CCACCGGTTCGCGCTTTCGCCGCAATCGCCTCAATCGCCGCGCACGGCGGCGCACTGTGCAGTTGAAACGCGCACTGTGT
TTTTGTACAGTATCGGCACC

Downstream 100 bases:

>100_bases
TCGAACGCGCGGCCGCGCGCGGCCTTGATGGCGCGATGAAAAAACGGCAACCCGCCGATGCGGGTTGCCGTTCGTCGTTG
CGCGGAGCCGGCGGGCGAGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDKPMPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYDARRYGVHSAMSS
ALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVS
AGVAPNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFG
RRLHELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSIRKLYVKIRFADFQRTT
VECVADATDADTAVALLAKGLARRRQAVRLLGVGVRIDEDTAERHGQIALFDDEDMSDESAEGDEGGEVGEGGEGGEDGE
GDEGDASPGA

Sequences:

>Translated_410_residues
MDKPMPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYDARRYGVHSAMSS
ALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVS
AGVAPNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFG
RRLHELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSIRKLYVKIRFADFQRTT
VECVADATDADTAVALLAKGLARRRQAVRLLGVGVRIDEDTAERHGQIALFDDEDMSDESAEGDEGGEVGEGGEGGEDGE
GDEGDASPGA
>Mature_410_residues
MDKPMPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRGVIATCNYDARRYGVHSAMSS
ALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEPLSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVS
AGVAPNKFIAKIASDWNKPDGLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFG
RRLHELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGAARSIRKLYVKIRFADFQRTT
VECVADATDADTAVALLAKGLARRRQAVRLLGVGVRIDEDTAERHGQIALFDDEDMSDESAEGDEGGEVGEGGEGGEDGE
GDEGDASPGA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=27.8592375366569, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=27.7777777777778, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI154350220, Length=325, Percent_Identity=28.9230769230769, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7705344, Length=113, Percent_Identity=47.787610619469, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI5729982, Length=367, Percent_Identity=26.7029972752044, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1786425, Length=350, Percent_Identity=47.4285714285714, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1787432, Length=231, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=436, Percent_Identity=27.7522935779816, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17537959, Length=291, Percent_Identity=29.8969072164948, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=379, Percent_Identity=25.3298153034301, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=127, Percent_Identity=38.5826771653543, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19923006, Length=346, Percent_Identity=26.878612716763, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=30.7420494699647, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=30.7420494699647, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24668444, Length=273, Percent_Identity=24.1758241758242, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44548; Mature: 44548

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPMPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCC
VIATCNYDARRYGVHSAMSSALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEP
EEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
LSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPD
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCC
GLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFG
CEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RRLHELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGA
HHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSIRKLYVKIRFADFQRTTVECVADATDADTAVALLAKGLARRRQAVRLLGVGVRIDED
HHHHHHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
TAERHGQIALFDDEDMSDESAEGDEGGEVGEGGEGGEDGEGDEGDASPGA
HHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDKPMPPSDPPPPPSGDAAHLARKIIHCDCDCFYASVEMRDDPSLRGRPLAVGGRPDQRG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCC
VIATCNYDARRYGVHSAMSSALAMRKCPDLLILPPAMDKYRAASRLIMAIYRDYTPDVEP
EEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
LSLDEAYLDVSRATRCQGSGTLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPD
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCC
GLFVVRPHEVDAFVAALPVRKLHGVGKVTAARLDKLGIRTCAQLRDWSLFDLHRTFGAFG
CEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RRLHELARGIDERPVRADQARKSVSVETTYVQDLAALDACAAEIRRLTGLLDARIERAGA
HHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSIRKLYVKIRFADFQRTTVECVADATDADTAVALLAKGLARRRQAVRLLGVGVRIDED
HHHHHHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
TAERHGQIALFDDEDMSDESAEGDEGGEVGEGGEGGEDGEGDEGDASPGA
HHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]