Click here to switch to the map view.

The map label for this gene is ahpF [H]

Identifier: 52787969

GI number: 52787969

Start: 4141254

End: 4142783

Strand: Direct

Name: ahpF [H]

Synonym: BLi04292

Alternate gene names: 52787969

Gene position: 4141254-4142783 (Clockwise)

Preceding gene: 52787968

Following gene: 52787972

Centisome position: 98.07

GC content: 51.37

Gene sequence:

>1530_bases
TTGGTACTTGAAGCAAATATCAAAGCACAATTAAACCAATACATGCAGATGATTGAAAATGACATCGTCCTTAAAGTCAG
TGCAGGCGATGACAGTGTCTCTAAGGATATGCTGGCTCTTGTAGAAGAGCTGGCTTCCATGTCATCAAAAATCACTGTTG
AAAAGGCGCAGCTCGACAGAACGCCAAGCTTCAGCGTCAATCGTGCCGAAGAAGATACAGGCGTGACATTCGCCGGGGTT
CCGCTCGGTCACGAATTCACATCTTTGGTGCTGGCACTCTTGCAAGTAAGCGGCAGACCGCCGAAAGTCGATCAAAAAAT
CATCGATCAAATCAAGAACATCAGCGGCGAGTACCGCTTCGAATCTTATATCAGCCTCACATGCCACAACTGCCCGGATG
TTGTGCAGGCATTGAACATGATGAGCGTGCTCAACCCGAACATCTCTCACACAATGATCGACGGTGCGGCATACAAGTCA
GAAGTCGAAAGCAAAAACATTATGGCTGTGCCGACCGTATACTTGAACGGCGAATCCTTTGGAAGCGGCCGAATGACGCT
TGAAGAAATTCTTGCGAAGATGGGCAGCGGCACAGATGCGTCTGAGCTTTCTGATAAAGAACCGTTCGATGTACTCGTTG
TCGGAGGCGGGCCTGCCGGCGCCAGCGCAGCAATCTATGCGGCGCGCAAAGGCATCCGTACGGGAATCGTTGCCGAACGC
TTCGGCGGCCAAGTCCTTGACACGATGAGCATCGAGAACTTCATCAGCGTGAAGCGCACCGAAGGGCCTAAGCTTGCGGC
AAGCCTTGAAGAACACGTGAAGGATTATGATATCGACGTCATGAACCTGCAACGAGCAAAAGGCCTCGAGAAAAAAGACC
TTTTCCATCTAGAACTCGAAAACGGCGCTGTTCTGAAGAGCAAAACCGTCATTCTTTCAACTGGCGCACGCTGGCGCAAT
ATCGGCGTACCCGGCGAACAAGAGTTCAAAAACAAAGGTGTCGCATACTGCCCTCACTGTGACGGACCATTGTTTGAAGG
CAAAGACGTCGCCGTCATCGGCGGCGGCAACTCCGGCATCGAAGCGGCGATTGACCTTGCAGGCATCGTCAACCATGTGA
CTGTTCTTGAGTTTGCGCCGGAGCTGAAAGCAGACAAAGTTCTGCAAAAACGTCTCTACAGCCTCCCCAACGTGACTGTC
GTGAAAAACGCCCAAACAAAAGAAATCACGGGCGATGAAAACGTAAACGGCATTACTTACGTAGACCGTGAAACAGGAGA
AGAAAAACACGTCGAGCTCCAAGGCGTCTTCGTCCAAATCGGTCTTGTGCCGAACACGGAATGGCTGCCTGAAACCGTCG
AACGCAACCGCATCGGCGAAATCGCAGTCGACAAACGCGGCGAAACAACCATCCCTGGATTGTTCGCTGCCGGCGACTGC
ACAGACAGCCCGTACAACCAAATCATCATTTCCATGGGATCCGGAGCAAACGCTGCTTTAGGCGCGTTTGACTACCTGAT
TCGGAATTAA

Upstream 100 bases:

>100_bases
CAAAACCCAGGCGAAGTTTGCCCGGCTAAATGGGAAGAAGGTTCTGAAACACTGACACCAAGCCTTGACCTAGTAGGCAA
AATCTAAGGAGTGCATTCAA

Downstream 100 bases:

>100_bases
TCTATAAAAAACGCTATGCTGAAGTTTTCAGCATAGCGTTTTTCTGTATTCCCGCAACCACGGCTCATTCGATTTTGGCA
ATGGAAGCATCCCTCAAGCA

Product: AhpF

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MVLEANIKAQLNQYMQMIENDIVLKVSAGDDSVSKDMLALVEELASMSSKITVEKAQLDRTPSFSVNRAEEDTGVTFAGV
PLGHEFTSLVLALLQVSGRPPKVDQKIIDQIKNISGEYRFESYISLTCHNCPDVVQALNMMSVLNPNISHTMIDGAAYKS
EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASELSDKEPFDVLVVGGGPAGASAAIYAARKGIRTGIVAER
FGGQVLDTMSIENFISVKRTEGPKLAASLEEHVKDYDIDVMNLQRAKGLEKKDLFHLELENGAVLKSKTVILSTGARWRN
IGVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADKVLQKRLYSLPNVTV
VKNAQTKEITGDENVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLPETVERNRIGEIAVDKRGETTIPGLFAAGDC
TDSPYNQIIISMGSGANAALGAFDYLIRN

Sequences:

>Translated_509_residues
MVLEANIKAQLNQYMQMIENDIVLKVSAGDDSVSKDMLALVEELASMSSKITVEKAQLDRTPSFSVNRAEEDTGVTFAGV
PLGHEFTSLVLALLQVSGRPPKVDQKIIDQIKNISGEYRFESYISLTCHNCPDVVQALNMMSVLNPNISHTMIDGAAYKS
EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASELSDKEPFDVLVVGGGPAGASAAIYAARKGIRTGIVAER
FGGQVLDTMSIENFISVKRTEGPKLAASLEEHVKDYDIDVMNLQRAKGLEKKDLFHLELENGAVLKSKTVILSTGARWRN
IGVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADKVLQKRLYSLPNVTV
VKNAQTKEITGDENVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLPETVERNRIGEIAVDKRGETTIPGLFAAGDC
TDSPYNQIIISMGSGANAALGAFDYLIRN
>Mature_509_residues
MVLEANIKAQLNQYMQMIENDIVLKVSAGDDSVSKDMLALVEELASMSSKITVEKAQLDRTPSFSVNRAEEDTGVTFAGV
PLGHEFTSLVLALLQVSGRPPKVDQKIIDQIKNISGEYRFESYISLTCHNCPDVVQALNMMSVLNPNISHTMIDGAAYKS
EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASELSDKEPFDVLVVGGGPAGASAAIYAARKGIRTGIVAER
FGGQVLDTMSIENFISVKRTEGPKLAASLEEHVKDYDIDVMNLQRAKGLEKKDLFHLELENGAVLKSKTVILSTGARWRN
IGVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADKVLQKRLYSLPNVTV
VKNAQTKEITGDENVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLPETVERNRIGEIAVDKRGETTIPGLFAAGDC
TDSPYNQIIISMGSGANAALGAFDYLIRN

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone [H]

COG id: COG3634

COG function: function code O; Alkyl hydroperoxide reductase, large subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=517, Percent_Identity=55.899419729207, Blast_Score=581, Evalue=1e-167,
Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=34.7402597402597, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321898, Length=327, Percent_Identity=32.1100917431193, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=33.2268370607029, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 55010; Mature: 55010

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00573 PYRIDINE_REDOX_2 ; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLEANIKAQLNQYMQMIENDIVLKVSAGDDSVSKDMLALVEELASMSSKITVEKAQLDR
CEEECHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEHHHCCC
TPSFSVNRAEEDTGVTFAGVPLGHEFTSLVLALLQVSGRPPKVDQKIIDQIKNISGEYRF
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEE
ESYISLTCHNCPDVVQALNMMSVLNPNISHTMIDGAAYKSEVESKNIMAVPTVYLNGESF
EEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCEEEEEEEEECCCCC
GSGRMTLEEILAKMGSGTDASELSDKEPFDVLVVGGGPAGASAAIYAARKGIRTGIVAER
CCCCCHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHCHHHHH
FGGQVLDTMSIENFISVKRTEGPKLAASLEEHVKDYDIDVMNLQRAKGLEKKDLFHLELE
HCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCEEEEEEC
NGAVLKSKTVILSTGARWRNIGVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGI
CCEEEEECEEEEECCCCEEECCCCCHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCCH
EAAIDLAGIVNHVTVLEFAPELKADKVLQKRLYSLPNVTVVKNAQTKEITGDENVNGITY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEE
VDRETGEEKHVELQGVFVQIGLVPNTEWLPETVERNRIGEIAVDKRGETTIPGLFAAGDC
EECCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHCCCCCEEECCCCCCCCCCEEECCCC
TDSPYNQIIISMGSGANAALGAFDYLIRN
CCCCCCEEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVLEANIKAQLNQYMQMIENDIVLKVSAGDDSVSKDMLALVEELASMSSKITVEKAQLDR
CEEECHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEHHHCCC
TPSFSVNRAEEDTGVTFAGVPLGHEFTSLVLALLQVSGRPPKVDQKIIDQIKNISGEYRF
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEE
ESYISLTCHNCPDVVQALNMMSVLNPNISHTMIDGAAYKSEVESKNIMAVPTVYLNGESF
EEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCEEEEEEEEECCCCC
GSGRMTLEEILAKMGSGTDASELSDKEPFDVLVVGGGPAGASAAIYAARKGIRTGIVAER
CCCCCHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHCHHHHH
FGGQVLDTMSIENFISVKRTEGPKLAASLEEHVKDYDIDVMNLQRAKGLEKKDLFHLELE
HCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCEEEEEEC
NGAVLKSKTVILSTGARWRNIGVPGEQEFKNKGVAYCPHCDGPLFEGKDVAVIGGGNSGI
CCEEEEECEEEEECCCCEEECCCCCHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCCH
EAAIDLAGIVNHVTVLEFAPELKADKVLQKRLYSLPNVTVVKNAQTKEITGDENVNGITY
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEE
VDRETGEEKHVELQGVFVQIGLVPNTEWLPETVERNRIGEIAVDKRGETTIPGLFAAGDC
EECCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHCCCCCEEECCCCCCCCCCEEECCCC
TDSPYNQIIISMGSGANAALGAFDYLIRN
CCCCCCEEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8125345; 8180695 [H]