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The map label for this gene is ahpC [H]

Identifier: 52787968

GI number: 52787968

Start: 4140677

End: 4141240

Strand: Direct

Name: ahpC [H]

Synonym: BLi04291

Alternate gene names: 52787968

Gene position: 4140677-4141240 (Clockwise)

Preceding gene: 52787967

Following gene: 52787969

Centisome position: 98.06

GC content: 45.92

Gene sequence:

>564_bases
ATGTCTCTAATCGGAAAAGAAGTACAACCATTCGCAGCAAAAGCTTACAAAAACGGTGAGTTTATCGATGTTACACACGA
AGATCTGAAAGGCCAATGGAGCATTTTCTGCTTCTATCCAGCGGATTTCTCATTTGTTTGCCCGACTGAGCTTGAAGACC
TTCAAAACCACTACGAAGCTCTAAAAGAACTAGGTGTCGAAGTATACTCTGTTTCTACAGATACTCACTTCGTACATAAA
GGATGGCATGACAGCTCTGAGAAAATCGGCAAAATCACTTACGCGATGATCGGCGACCCATCTCAAACGATCTCCCGCAA
TTTTGAAGTGCTGAACGAAGAAGAAGGTCTTGCTGACCGCGGAACATTCATCATCGATCCGGACGGCGTCATCCAAGCTG
TTGAAATCAACGCAGGCGGTATCGGCCGTGATGCGAGCATCCTGATCAACAAAGTAAAAGCGGCTCAATACGTACGCCAA
AACCCAGGCGAAGTTTGCCCGGCTAAATGGGAAGAAGGTTCTGAAACACTGACACCAAGCCTTGACCTAGTAGGCAAAAT
CTAA

Upstream 100 bases:

>100_bases
AATATTTATTATTTGATAATTTGTATATAATTATAATAATTATAGAGAAATAAAGTTTACAATTTTATTTCTCTTAAACT
ACATTCAGGAGGACGATATT

Downstream 100 bases:

>100_bases
GGAGTGCATTCAATTGGTACTTGAAGCAAATATCAAAGCACAATTAAACCAATACATGCAGATGATTGAAAATGACATCG
TCCTTAAAGTCAGTGCAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLIGKEVQPFAAKAYKNGEFIDVTHEDLKGQWSIFCFYPADFSFVCPTELEDLQNHYEALKELGVEVYSVSTDTHFVHK
GWHDSSEKIGKITYAMIGDPSQTISRNFEVLNEEEGLADRGTFIIDPDGVIQAVEINAGGIGRDASILINKVKAAQYVRQ
NPGEVCPAKWEEGSETLTPSLDLVGKI

Sequences:

>Translated_187_residues
MSLIGKEVQPFAAKAYKNGEFIDVTHEDLKGQWSIFCFYPADFSFVCPTELEDLQNHYEALKELGVEVYSVSTDTHFVHK
GWHDSSEKIGKITYAMIGDPSQTISRNFEVLNEEEGLADRGTFIIDPDGVIQAVEINAGGIGRDASILINKVKAAQYVRQ
NPGEVCPAKWEEGSETLTPSLDLVGKI
>Mature_186_residues
SLIGKEVQPFAAKAYKNGEFIDVTHEDLKGQWSIFCFYPADFSFVCPTELEDLQNHYEALKELGVEVYSVSTDTHFVHKG
WHDSSEKIGKITYAMIGDPSQTISRNFEVLNEEEGLADRGTFIIDPDGVIQAVEINAGGIGRDASILINKVKAAQYVRQN
PGEVCPAKWEEGSETLTPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=42.1965317919075, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=42.1965317919075, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=39.010989010989, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=36.8131868131868, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=36.8131868131868, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=36.8131868131868, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=34.7593582887701, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI33188454, Length=85, Percent_Identity=42.3529411764706, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=65.7754010695187, Blast_Score=280, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=38.7978142076503, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=38.7978142076503, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=36.1581920903955, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=32.5966850828729, Blast_Score=117, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=34.0659340659341, Blast_Score=117, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357347, Length=185, Percent_Identity=36.7567567567568, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17738015, Length=171, Percent_Identity=37.4269005847953, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=35, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=35, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=34.6153846153846, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=34.6153846153846, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20713; Mature: 20582

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIGKEVQPFAAKAYKNGEFIDVTHEDLKGQWSIFCFYPADFSFVCPTELEDLQNHYEA
CCCCCCCCCHHHHHHCCCCCEEEEEHHCCCCCEEEEEEECCCCCEECCHHHHHHHHHHHH
LKELGVEVYSVSTDTHFVHKGWHDSSEKIGKITYAMIGDPSQTISRNFEVLNEEEGLADR
HHHCCCEEEEECCCCEEEECCCCCCCHHHCEEEEEEECCCHHHHHCCHHEECCCCCCCCC
GTFIIDPDGVIQAVEINAGGIGRDASILINKVKAAQYVRQNPGEVCPAKWEEGSETLTPS
CCEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLVGKI
HHEEECC
>Mature Secondary Structure 
SLIGKEVQPFAAKAYKNGEFIDVTHEDLKGQWSIFCFYPADFSFVCPTELEDLQNHYEA
CCCCCCCCHHHHHHCCCCCEEEEEHHCCCCCEEEEEEECCCCCEECCHHHHHHHHHHHH
LKELGVEVYSVSTDTHFVHKGWHDSSEKIGKITYAMIGDPSQTISRNFEVLNEEEGLADR
HHHCCCEEEEECCCCEEEECCCCCCCHHHCEEEEEEECCCHHHHHCCHHEECCCCCCCCC
GTFIIDPDGVIQAVEINAGGIGRDASILINKVKAAQYVRQNPGEVCPAKWEEGSETLTPS
CCEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLVGKI
HHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 8180695; 8012595 [H]