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The map label for this gene is iolR [H]

Identifier: 52787929

GI number: 52787929

Start: 4091376

End: 4092140

Strand: Direct

Name: iolR [H]

Synonym: BLi04252

Alternate gene names: 52787929

Gene position: 4091376-4092140 (Clockwise)

Preceding gene: 52787913

Following gene: 52787930

Centisome position: 96.89

GC content: 41.96

Gene sequence:

>765_bases
ATGAAGTTAATGCGGATTAAAGAAATGGAAGATTATATTTTGACCAATGGCACCGTTTCGCTTGATGAACTATGCCAGGT
CTTTAATGTTTCAAAAAACACGGTCAGACGCGACATTAACAAGCTGACCGAGAAAGGAGTTATAAAAAAAGTCTACGGCG
GCGTAACAGCGATCGAAAAAACGGCCTTGATCCCTTTTGAAAACAGAACCATTCAAAACAAGGATGCCAAGACAAAAATC
GCGCGCTATGCTTCACGCTTTATTGAAGACCATGACCTGATTTTTATTGATTCCGGCACAACGACCCGATCCATATTGGA
AACTCTTGATCCAAATAAAAATGTAACCGTTTTAACGAACAGCCTCGACATTATCAACGCTGCTGCAGCGATGCAAAATA
TAAACTTGATCATCATCGGCAGCAACTACAAACGGAAAACGCAGTCCTTCGTCGGCATGGATGATCCGGGAACGCTGGAT
AAATATAATATTAATAAAGCTTTCATGTCGGCAACCGGCGCAACACTTACCCATGGACTGACAAACTCCGATCTGCTTGA
ATATGAAATTAAAAAGAAAATATCCGAAAAAGCAAAACAAGTATATTTGCTGGCCGACCATTCCAAATTCGGGAAGTCGA
CCCTGCTGACGTACGCGCCGTTTGACAGATTGCACGCGATCGTCACATCTCAGGCGCTTGATGAGGAATATCACGTGTAC
TGTAAAGATCGCAAAATTGAAATCCATTTGGCAAAACATGTATAG

Upstream 100 bases:

>100_bases
AAAAATAATCACCAATGGTATCATTTTTTAAGCAATTATTGGTTAACTTTTGGGTTCGTCATATATATTTAGTCAAATAT
ACTAGAAGGAGATACTTAGT

Downstream 100 bases:

>100_bases
TTGAAGCGGACACCCTTGACCGGCTGTTTCCAAGCGGCCGGCCAAGTTTATTTATCTACACATCATATCAGGAGGGGAAT
TCAATGAAAAAAGTTAAAGT

Product: IolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKLMRIKEMEDYILTNGTVSLDELCQVFNVSKNTVRRDINKLTEKGVIKKVYGGVTAIEKTALIPFENRTIQNKDAKTKI
ARYASRFIEDHDLIFIDSGTTTRSILETLDPNKNVTVLTNSLDIINAAAAMQNINLIIIGSNYKRKTQSFVGMDDPGTLD
KYNINKAFMSATGATLTHGLTNSDLLEYEIKKKISEKAKQVYLLADHSKFGKSTLLTYAPFDRLHAIVTSQALDEEYHVY
CKDRKIEIHLAKHV

Sequences:

>Translated_254_residues
MKLMRIKEMEDYILTNGTVSLDELCQVFNVSKNTVRRDINKLTEKGVIKKVYGGVTAIEKTALIPFENRTIQNKDAKTKI
ARYASRFIEDHDLIFIDSGTTTRSILETLDPNKNVTVLTNSLDIINAAAAMQNINLIIIGSNYKRKTQSFVGMDDPGTLD
KYNINKAFMSATGATLTHGLTNSDLLEYEIKKKISEKAKQVYLLADHSKFGKSTLLTYAPFDRLHAIVTSQALDEEYHVY
CKDRKIEIHLAKHV
>Mature_254_residues
MKLMRIKEMEDYILTNGTVSLDELCQVFNVSKNTVRRDINKLTEKGVIKKVYGGVTAIEKTALIPFENRTIQNKDAKTKI
ARYASRFIEDHDLIFIDSGTTTRSILETLDPNKNVTVLTNSLDIINAAAAMQNINLIIIGSNYKRKTQSFVGMDDPGTLD
KYNINKAFMSATGATLTHGLTNSDLLEYEIKKKISEKAKQVYLLADHSKFGKSTLLTYAPFDRLHAIVTSQALDEEYHVY
CKDRKIEIHLAKHV

Specific function: Iol operon repressor [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=239, Percent_Identity=29.2887029288703, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788069, Length=248, Percent_Identity=30.241935483871, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789829, Length=235, Percent_Identity=25.531914893617, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789519, Length=222, Percent_Identity=26.1261261261261, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI226510968, Length=228, Percent_Identity=29.3859649122807, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=239, Percent_Identity=24.6861924686192, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082344, Length=241, Percent_Identity=25.7261410788382, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790753, Length=254, Percent_Identity=25.9842519685039, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790635, Length=223, Percent_Identity=28.6995515695067, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787063, Length=249, Percent_Identity=24.8995983935743, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28693; Mature: 28693

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMRIKEMEDYILTNGTVSLDELCQVFNVSKNTVRRDINKLTEKGVIKKVYGGVTAIEK
CCCCHHHHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TALIPFENRTIQNKDAKTKIARYASRFIEDHDLIFIDSGTTTRSILETLDPNKNVTVLTN
EEECCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEC
SLDIINAAAAMQNINLIIIGSNYKRKTQSFVGMDDPGTLDKYNINKAFMSATGATLTHGL
CHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCCCCCCCEECHHHHHHHCCCHHCCCC
TNSDLLEYEIKKKISEKAKQVYLLADHSKFGKSTLLTYAPFDRLHAIVTSQALDEEYHVY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEE
CKDRKIEIHLAKHV
EECCEEEEEEECCC
>Mature Secondary Structure
MKLMRIKEMEDYILTNGTVSLDELCQVFNVSKNTVRRDINKLTEKGVIKKVYGGVTAIEK
CCCCHHHHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TALIPFENRTIQNKDAKTKIARYASRFIEDHDLIFIDSGTTTRSILETLDPNKNVTVLTN
EEECCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEC
SLDIINAAAAMQNINLIIIGSNYKRKTQSFVGMDDPGTLDKYNINKAFMSATGATLTHGL
CHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCCCCCCCEECHHHHHHHCCCHHCCCC
TNSDLLEYEIKKKISEKAKQVYLLADHSKFGKSTLLTYAPFDRLHAIVTSQALDEEYHVY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEE
CKDRKIEIHLAKHV
EECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]