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The map label for this gene is yqiQ [H]

Identifier: 52787773

GI number: 52787773

Start: 3920653

End: 3921570

Strand: Direct

Name: yqiQ [H]

Synonym: BLi04096

Alternate gene names: 52787773

Gene position: 3920653-3921570 (Clockwise)

Preceding gene: 52787772

Following gene: 52787778

Centisome position: 92.85

GC content: 51.09

Gene sequence:

>918_bases
ATGTGGATTGTCTCGAAACAATCAACTCAGGAAGAGCTGGCCAATGCATTCAGAAAACTGATGAAAGCACCTGATATTTT
GAAAATACCCGGTGTTCATGACGGAATGGCTGCCATTACCGCAAAAAACATCGGCTTCAAAGCGCTCTATCTCTCCGGGG
CCGCCTACACGGCAAGCCGCGGGCTCCCTGACCTCGGAATGATACACTCCCAGGAAATCGCTGAAAAAGCAAGCGAACTT
GTGAGAGCCGCAAATCTTCCGCTTTTGGTCGATATCGACACCGGCTACGGCGGTGTCCTAAATGCGGCACGCACGGCCGC
CGAAATGGCCGAGAGCAGAGTCGCAGCCGTCCAAATCGAAGATCAGCAACTGCCTAAAAAATGCGGACATTTAAATGGAA
AAACGCTCGTACCCGCAGAGGACATGATCGCAAAAATTAGAGCGATAAAAGAAACCGCCCCTTCGCTCGTTGTCGTGGCT
CGGACGGATGCAAAAGCAGCAGAAGGGATGGAAGCCGCCGTCAGGCGCGCCAATTTATATGCCGACGCGGGAGCCGATGC
CATCTTTCCTGAAGCATTAACGAGCGCAGCCGAATTCCGGGAAATGGCTTCTTCCATTAAAGCGCCGCTCCTGGCCAATA
TGACCGAATTCGGAAAAACGCCTTATTATACGGCTGACGAATTCCAAATGCTCGGCTGCAGCATGATTATTTACCCTGTG
ACTTCCCTGCGCGCCGCCGCGAAAGCTTATGAGCGGGTCTTCGCGGAGATTTTCGAAAAAGGCACGCAAAAGGGTGTGCT
CGATGACATGCAGACACGCGAAGAATTATATGATGCGATTCATTACTACGACTATGAAAAACTGGACGAAAATATTGCCA
AAACGGTGCTTCCCGAAATCGGAAAAGAACACCGTTGA

Upstream 100 bases:

>100_bases
AGCGGAACGAATCAACGCCCTGCTGAATGATCCTCACAGATTAAGCGGTGCACCTGTACCGGATTTCATGGAATTGTTTG
TCATTTAGGAGGTTTTGAAT

Downstream 100 bases:

>100_bases
TACGCGAAACAAGGCTGCCGAATGATCGGCAGCCTTCTCCACTTACAACAGCTGCAACATCGCACCGCCGACAGCACCGG
CTGCAACGATGATCCACGGC

Product: YqiQ

Products: NA

Alternate protein names: 2-methylisocitrate lyase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MWIVSKQSTQEELANAFRKLMKAPDILKIPGVHDGMAAITAKNIGFKALYLSGAAYTASRGLPDLGMIHSQEIAEKASEL
VRAANLPLLVDIDTGYGGVLNAARTAAEMAESRVAAVQIEDQQLPKKCGHLNGKTLVPAEDMIAKIRAIKETAPSLVVVA
RTDAKAAEGMEAAVRRANLYADAGADAIFPEALTSAAEFREMASSIKAPLLANMTEFGKTPYYTADEFQMLGCSMIIYPV
TSLRAAAKAYERVFAEIFEKGTQKGVLDDMQTREELYDAIHYYDYEKLDENIAKTVLPEIGKEHR

Sequences:

>Translated_305_residues
MWIVSKQSTQEELANAFRKLMKAPDILKIPGVHDGMAAITAKNIGFKALYLSGAAYTASRGLPDLGMIHSQEIAEKASEL
VRAANLPLLVDIDTGYGGVLNAARTAAEMAESRVAAVQIEDQQLPKKCGHLNGKTLVPAEDMIAKIRAIKETAPSLVVVA
RTDAKAAEGMEAAVRRANLYADAGADAIFPEALTSAAEFREMASSIKAPLLANMTEFGKTPYYTADEFQMLGCSMIIYPV
TSLRAAAKAYERVFAEIFEKGTQKGVLDDMQTREELYDAIHYYDYEKLDENIAKTVLPEIGKEHR
>Mature_305_residues
MWIVSKQSTQEELANAFRKLMKAPDILKIPGVHDGMAAITAKNIGFKALYLSGAAYTASRGLPDLGMIHSQEIAEKASEL
VRAANLPLLVDIDTGYGGVLNAARTAAEMAESRVAAVQIEDQQLPKKCGHLNGKTLVPAEDMIAKIRAIKETAPSLVVVA
RTDAKAAEGMEAAVRRANLYADAGADAIFPEALTSAAEFREMASSIKAPLLANMTEFGKTPYYTADEFQMLGCSMIIYPV
TSLRAAAKAYERVFAEIFEKGTQKGVLDDMQTREELYDAIHYYDYEKLDENIAKTVLPEIGKEHR

Specific function: Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=285, Percent_Identity=42.8070175438597, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1790445, Length=256, Percent_Identity=28.90625, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561814, Length=185, Percent_Identity=28.6486486486486, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982926, Length=185, Percent_Identity=28.6486486486486, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000918
- InterPro:   IPR018523
- InterPro:   IPR012695
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =4.1.3.30 [H]

Molecular weight: Translated: 33237; Mature: 33237

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00161 ISOCITRATE_LYASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIVSKQSTQEELANAFRKLMKAPDILKIPGVHDGMAAITAKNIGFKALYLSGAAYTASR
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHHHC
GLPDLGMIHSQEIAEKASELVRAANLPLLVDIDTGYGGVLNAARTAAEMAESRVAAVQIE
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEC
DQQLPKKCGHLNGKTLVPAEDMIAKIRAIKETAPSLVVVARTDAKAAEGMEAAVRRANLY
HHHHHHHHCCCCCCEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
ADAGADAIFPEALTSAAEFREMASSIKAPLLANMTEFGKTPYYTADEFQMLGCSMIIYPV
HCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TSLRAAAKAYERVFAEIFEKGTQKGVLDDMQTREELYDAIHYYDYEKLDENIAKTVLPEI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKEHR
CCCCC
>Mature Secondary Structure
MWIVSKQSTQEELANAFRKLMKAPDILKIPGVHDGMAAITAKNIGFKALYLSGAAYTASR
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHHHC
GLPDLGMIHSQEIAEKASELVRAANLPLLVDIDTGYGGVLNAARTAAEMAESRVAAVQIE
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEC
DQQLPKKCGHLNGKTLVPAEDMIAKIRAIKETAPSLVVVARTDAKAAEGMEAAVRRANLY
HHHHHHHHCCCCCCEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
ADAGADAIFPEALTSAAEFREMASSIKAPLLANMTEFGKTPYYTADEFQMLGCSMIIYPV
HCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TSLRAAAKAYERVFAEIFEKGTQKGVLDDMQTREELYDAIHYYDYEKLDENIAKTVLPEI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKEHR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]