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The map label for this gene is xylA

Identifier: 52787725

GI number: 52787725

Start: 3874562

End: 3875908

Strand: Reverse

Name: xylA

Synonym: BLi04048

Alternate gene names: 52787725

Gene position: 3875908-3874562 (Counterclockwise)

Preceding gene: 52787728

Following gene: 52787724

Centisome position: 91.79

GC content: 47.14

Gene sequence:

>1347_bases
ATGTTTTTTAGAAATATCGGAATGATTGAGTATGAAGGGGCCGATTCGGAAAATCCTTACGCATTTAAATATTACAACCC
TGATGAATTTGTCGGCGGCAAAACGATGAAGGAACACCTTCGCTTCGCTGTTGCGTATTGGCATACCTTTGATGCGGACG
GGAAAGACCCTTTCGGCGACGGGACGATGTTCCGGGCGTGGAACCGGCTGACACATCCTTTGGATAAAGCGAAAGCCAGG
GCGGAAGCGGCTTTTGAATTTTTTGAAAAGCTCGGCGTGCCCTATTTCTGTTTTCATGATGTTGATATTGTCGATGAAGG
AGCAACATTGCGTGAAACTTTCACGTATTTGGATCAAATGTCGTCTTTTCTCAAAGAAATGATGGAGACAAGCCATGTTC
AGCTGCTTTGGAATACAGCCAATATGTTTACGCATCCGAGATATGTCCACGGGGCCGCAACTTCTTGCAATGCAGACGTC
TATGCCTATGCAGCTGCAAAAGTGAAAAAAGGCCTGGACATCGCCAAAGAGCTTGGAGCGGAAAACTATGTGTTCTGGGG
CGGAAGAGAAGGTTATGAAACATTGCTGAATACAGATATGAAGCTTGAGCTCGAAAACTTGTCTTCATTTTATAGAATGG
CAGTTGAGTATGCGCGTGAAATCGGTTTTGACGGCCAATTTTTAATCGAGCCGAAGCCGAAGGAGCCGACGAAGCACCAA
TACGATTTTGATGCAGCCACAACGATCGCTTTTTTAGAAACTTACGGTTTAAAAGACCATTTTAAACTTAATCTTGAGGC
GAACCATGCGACATTGGCCGGGCATACATTTGAGCATGAACTAAGGGTGGCTGCCTTGCACGATATGCTGGGTTCCATTG
ATGCCAACCAGGGCGATTTGCTCTTGGGCTGGGATACCGATGAGTTTCCGACCGATCTGTATTCTGCGGTTCTGGCGATG
TATGAAATTTTGAAAGCAGGCGGGTTTAAAACCGGCGGCATCAACTTCGATGCTAAAGTAAGGCGCCCGTCATTTGCCGA
TGAGGACTTGTTTCACGCTCATATCGCAGGAATGGATACGTATGCAGTCGGCTTGAAAGTCGCCTCCCGTCTGCTTGAAG
ATAAAGCGCTCGATCAGGTTATCGAAGAACGTTATGAGAGCTATACGAAAGGCATCGGGCTTGAAATCAAAGAAGGCCGC
ACCGATCTGAAAAAGCTCGCCGCTTACGCTCTTGAAAACGACCATATTGAAAATCAGTCAGGCCGCCAAGAACGGCTGAA
GGCGACCGTTAACCGTTACTTATTGAACGCTTTGCGCGAAGCGCCGGCAGGAAAGGAGACACACTAG

Upstream 100 bases:

>100_bases
ATTAATTGATCCTGTAAAATACATACAAGGAAGTTAGTTTAATGGTTAAACAAACATTGTTTTTTAACGTTTGCAAGGAA
AAGTGAAGGGGGAGATCGGA

Downstream 100 bases:

>100_bases
TGGAATACGTAATCGGGGTCGATCTCGGCACCAGCACGGTTAAAATCATCCTTGTCAATCAGCGGGGAGAGCTGTGCGGC
GAGGTCTCCAAACCGTTTTC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MFFRNIGMIEYEGADSENPYAFKYYNPDEFVGGKTMKEHLRFAVAYWHTFDADGKDPFGDGTMFRAWNRLTHPLDKAKAR
AEAAFEFFEKLGVPYFCFHDVDIVDEGATLRETFTYLDQMSSFLKEMMETSHVQLLWNTANMFTHPRYVHGAATSCNADV
YAYAAAKVKKGLDIAKELGAENYVFWGGREGYETLLNTDMKLELENLSSFYRMAVEYAREIGFDGQFLIEPKPKEPTKHQ
YDFDAATTIAFLETYGLKDHFKLNLEANHATLAGHTFEHELRVAALHDMLGSIDANQGDLLLGWDTDEFPTDLYSAVLAM
YEILKAGGFKTGGINFDAKVRRPSFADEDLFHAHIAGMDTYAVGLKVASRLLEDKALDQVIEERYESYTKGIGLEIKEGR
TDLKKLAAYALENDHIENQSGRQERLKATVNRYLLNALREAPAGKETH

Sequences:

>Translated_448_residues
MFFRNIGMIEYEGADSENPYAFKYYNPDEFVGGKTMKEHLRFAVAYWHTFDADGKDPFGDGTMFRAWNRLTHPLDKAKAR
AEAAFEFFEKLGVPYFCFHDVDIVDEGATLRETFTYLDQMSSFLKEMMETSHVQLLWNTANMFTHPRYVHGAATSCNADV
YAYAAAKVKKGLDIAKELGAENYVFWGGREGYETLLNTDMKLELENLSSFYRMAVEYAREIGFDGQFLIEPKPKEPTKHQ
YDFDAATTIAFLETYGLKDHFKLNLEANHATLAGHTFEHELRVAALHDMLGSIDANQGDLLLGWDTDEFPTDLYSAVLAM
YEILKAGGFKTGGINFDAKVRRPSFADEDLFHAHIAGMDTYAVGLKVASRLLEDKALDQVIEERYESYTKGIGLEIKEGR
TDLKKLAAYALENDHIENQSGRQERLKATVNRYLLNALREAPAGKETH
>Mature_448_residues
MFFRNIGMIEYEGADSENPYAFKYYNPDEFVGGKTMKEHLRFAVAYWHTFDADGKDPFGDGTMFRAWNRLTHPLDKAKAR
AEAAFEFFEKLGVPYFCFHDVDIVDEGATLRETFTYLDQMSSFLKEMMETSHVQLLWNTANMFTHPRYVHGAATSCNADV
YAYAAAKVKKGLDIAKELGAENYVFWGGREGYETLLNTDMKLELENLSSFYRMAVEYAREIGFDGQFLIEPKPKEPTKHQ
YDFDAATTIAFLETYGLKDHFKLNLEANHATLAGHTFEHELRVAALHDMLGSIDANQGDLLLGWDTDEFPTDLYSAVLAM
YEILKAGGFKTGGINFDAKVRRPSFADEDLFHAHIAGMDTYAVGLKVASRLLEDKALDQVIEERYESYTKGIGLEIKEGR
TDLKKLAAYALENDHIENQSGRQERLKATVNRYLLNALREAPAGKETH

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=437, Percent_Identity=53.5469107551487, Blast_Score=480, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_BACLD (P77832)

Other databases:

- EMBL:   Z80222
- EMBL:   X57601
- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_081127.1
- RefSeq:   YP_093554.1
- ProteinModelPortal:   P77832
- SMR:   P77832
- STRING:   P77832
- EnsemblBacteria:   EBBACT00000054826
- EnsemblBacteria:   EBBACT00000060117
- GeneID:   3030684
- GeneID:   3101267
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi04048
- KEGG:   bli:BL03867
- NMPDR:   fig|279010.5.peg.3169
- eggNOG:   COG2115
- GeneTree:   EBGT00050000002648
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- BioCyc:   BLIC279010-1:BLI04048-MONOMER
- BioCyc:   BLIC279010:BL03867-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 50906; Mature: 50906

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 99-99 ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFRNIGMIEYEGADSENPYAFKYYNPDEFVGGKTMKEHLRFAVAYWHTFDADGKDPFGD
CCEECCCEEEECCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCC
GTMFRAWNRLTHPLDKAKARAEAAFEFFEKLGVPYFCFHDVDIVDEGATLRETFTYLDQM
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCHHHHHHHHHHHH
SSFLKEMMETSHVQLLWNTANMFTHPRYVHGAATSCNADVYAYAAAKVKKGLDIAKELGA
HHHHHHHHHCCCEEEEEECHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ENYVFWGGREGYETLLNTDMKLELENLSSFYRMAVEYAREIGFDGQFLIEPKPKEPTKHQ
CCEEEECCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
YDFDAATTIAFLETYGLKDHFKLNLEANHATLAGHTFEHELRVAALHDMLGSIDANQGDL
CCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCE
LLGWDTDEFPTDLYSAVLAMYEILKAGGFKTGGINFDAKVRRPSFADEDLFHAHIAGMDT
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHCCCHH
YAVGLKVASRLLEDKALDQVIEERYESYTKGIGLEIKEGRTDLKKLAAYALENDHIENQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCCCCCCC
GRQERLKATVNRYLLNALREAPAGKETH
CHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFFRNIGMIEYEGADSENPYAFKYYNPDEFVGGKTMKEHLRFAVAYWHTFDADGKDPFGD
CCEECCCEEEECCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCC
GTMFRAWNRLTHPLDKAKARAEAAFEFFEKLGVPYFCFHDVDIVDEGATLRETFTYLDQM
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCHHHHHHHHHHHH
SSFLKEMMETSHVQLLWNTANMFTHPRYVHGAATSCNADVYAYAAAKVKKGLDIAKELGA
HHHHHHHHHCCCEEEEEECHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ENYVFWGGREGYETLLNTDMKLELENLSSFYRMAVEYAREIGFDGQFLIEPKPKEPTKHQ
CCEEEECCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
YDFDAATTIAFLETYGLKDHFKLNLEANHATLAGHTFEHELRVAALHDMLGSIDANQGDL
CCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCE
LLGWDTDEFPTDLYSAVLAMYEILKAGGFKTGGINFDAKVRRPSFADEDLFHAHIAGMDT
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHCCCHH
YAVGLKVASRLLEDKALDQVIEERYESYTKGIGLEIKEGRTDLKKLAAYALENDHIENQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCCCCCCC
GRQERLKATVNRYLLNALREAPAGKETH
CHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1953294