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The map label for this gene is rho [H]

Identifier: 52787634

GI number: 52787634

Start: 3780008

End: 3781291

Strand: Reverse

Name: rho [H]

Synonym: BLi03956

Alternate gene names: 52787634

Gene position: 3781291-3780008 (Counterclockwise)

Preceding gene: 52787635

Following gene: 52787633

Centisome position: 89.55

GC content: 48.44

Gene sequence:

>1284_bases
GTGAAAGATGTATCCATTTCATCTTTGGAAAATATGAAATTAAAAGAGCTGTATGAGCTTGCAAGGCATTATAAAGTCTC
TTATTACAGCAAACTGACAAAAAAGGAACTGATTTTTGCCATTCTGAAAGCAAACGCCGAACAGGAAGATCTGCTGTTCA
TGGAAGGCGTATTGGAAATCATCCAGTCCGAAGGGTTCGGCTTTCTCAGACCGATCAACTACTCGCCTAGTTCAGAGGAT
ATCTATATTTCCGCCTCACAAATCCGCCGTTTTGATTTGAGAAACGGTGATAAAGTGTCCGGAAAGGTCCGCCCTCCAAA
AGAAAACGAACGGTATTACGGCCTGCTGCACGTTGAAGCGGTTAACGGCGACGATCCTGAATCAGCAAAAGAACGCGTGC
ACTTTCCGGCATTAACGCCTCTTTATCCAGATCGCCAGATGGTGCTTGAAACGAAGCCGAATCACCTGTCAACACGGATC
ATGGACATGATGGCGCCGGTCGGCTTTGGACAGCGCGGTCTGATCGTCGCTCCGCCTAAAGCGGGTAAAACCATGCTCTT
GAAAGAGATCGCGAACAGCATCACAACCAATCATCCGGAAGCGGAGCTGATCGTGCTTCTTATCGATGAAAGACCTGAGG
AAGTGACCGACATCGAACGTTCGGTTGCAGGAGACGTTGTCAGCTCAACGTTTGACGAAGTTCCTGAAAACCATATCAAG
GTGGCCGAGCTTGTATTGGAACGTGCAATGAGGCTTGTTGAGCATAAAAAGGACGTTATCATTTTAATGGACAGCATTAC
AAGGCTTGCCCGCGCCTATAACCTTGTCATTCCGCCGAGCGGCAGAACGTTGTCCGGGGGAATCGATCCCGGCGCTTTCC
ACCGTCCAAAGCGTTTCTTTGGAGCAGCCCGCAACATTGAAGAGGGCGGCAGCTTAACGATCCTGGCGACCGCTCTCGTC
GACACGGGCTCGCGGATGGATGACGTCATCTATGAGGAATTTAAAGGAACAGGGAACATGGAGCTTCATCTTGACCGTTC
TCTTGCGGAAAGAAGAATCTTTCCTGCCATTGATATTCGCCGTTCGGGTACGCGTAAAGAAGAGCTTCTCGTTCCGAAAG
AGCACCTTGATCGTCTGTGGTCAATCCGGAAAACGATGTCTGACACGCCTGACTTCGTCGAGAAATTCATGAGAAAAATG
AAAAAGACGAAAACGAATCAGGAGTTTTTCGATATTCTGATCCAGGAATGGAAACAAGCCAATATGTCTGCTGCAAGGCG
CTGA

Upstream 100 bases:

>100_bases
AGCGTTGCCGGTAAAACGAATCGGCAGTATACATTAATCGTCTTTCGTGAAATTGATGAGACAAAGTAAATTATTCGATT
AGAAAAGAGTGGTGTTCTTA

Downstream 100 bases:

>100_bases
TTTAAAACTTTAGTTTGCAAAACGTCCGAATCGCTGTTATAATTCTATCATGTGCGTTCCGGAGGTTTTGCCCCGGAATA
ATAACTCTGTTTCCGAATTG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKDVSISSLENMKLKELYELARHYKVSYYSKLTKKELIFAILKANAEQEDLLFMEGVLEIIQSEGFGFLRPINYSPSSED
IYISASQIRRFDLRNGDKVSGKVRPPKENERYYGLLHVEAVNGDDPESAKERVHFPALTPLYPDRQMVLETKPNHLSTRI
MDMMAPVGFGQRGLIVAPPKAGKTMLLKEIANSITTNHPEAELIVLLIDERPEEVTDIERSVAGDVVSSTFDEVPENHIK
VAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPGAFHRPKRFFGAARNIEEGGSLTILATALV
DTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIRRSGTRKEELLVPKEHLDRLWSIRKTMSDTPDFVEKFMRKM
KKTKTNQEFFDILIQEWKQANMSAARR

Sequences:

>Translated_427_residues
MKDVSISSLENMKLKELYELARHYKVSYYSKLTKKELIFAILKANAEQEDLLFMEGVLEIIQSEGFGFLRPINYSPSSED
IYISASQIRRFDLRNGDKVSGKVRPPKENERYYGLLHVEAVNGDDPESAKERVHFPALTPLYPDRQMVLETKPNHLSTRI
MDMMAPVGFGQRGLIVAPPKAGKTMLLKEIANSITTNHPEAELIVLLIDERPEEVTDIERSVAGDVVSSTFDEVPENHIK
VAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPGAFHRPKRFFGAARNIEEGGSLTILATALV
DTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIRRSGTRKEELLVPKEHLDRLWSIRKTMSDTPDFVEKFMRKM
KKTKTNQEFFDILIQEWKQANMSAARR
>Mature_427_residues
MKDVSISSLENMKLKELYELARHYKVSYYSKLTKKELIFAILKANAEQEDLLFMEGVLEIIQSEGFGFLRPINYSPSSED
IYISASQIRRFDLRNGDKVSGKVRPPKENERYYGLLHVEAVNGDDPESAKERVHFPALTPLYPDRQMVLETKPNHLSTRI
MDMMAPVGFGQRGLIVAPPKAGKTMLLKEIANSITTNHPEAELIVLLIDERPEEVTDIERSVAGDVVSSTFDEVPENHIK
VAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPGAFHRPKRFFGAARNIEEGGSLTILATALV
DTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIRRSGTRKEELLVPKEHLDRLWSIRKTMSDTPDFVEKFMRKM
KKTKTNQEFFDILIQEWKQANMSAARR

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=417, Percent_Identity=57.0743405275779, Blast_Score=489, Evalue=1e-139,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 48674; Mature: 48674

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVSISSLENMKLKELYELARHYKVSYYSKLTKKELIFAILKANAEQEDLLFMEGVLEI
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IQSEGFGFLRPINYSPSSEDIYISASQIRRFDLRNGDKVSGKVRPPKENERYYGLLHVEA
HHHCCCCEEEECCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEE
VNGDDPESAKERVHFPALTPLYPDRQMVLETKPNHLSTRIMDMMAPVGFGQRGLIVAPPK
ECCCCCHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCC
AGKTMLLKEIANSITTNHPEAELIVLLIDERPEEVTDIERSVAGDVVSSTFDEVPENHIK
CCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPGAFHRPKRFF
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCHHHH
GAARNIEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIR
HHHCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCEECC
RSGTRKEELLVPKEHLDRLWSIRKTMSDTPDFVEKFMRKMKKTKTNQEFFDILIQEWKQA
CCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NMSAARR
HHHHCCC
>Mature Secondary Structure
MKDVSISSLENMKLKELYELARHYKVSYYSKLTKKELIFAILKANAEQEDLLFMEGVLEI
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IQSEGFGFLRPINYSPSSEDIYISASQIRRFDLRNGDKVSGKVRPPKENERYYGLLHVEA
HHHCCCCEEEECCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEE
VNGDDPESAKERVHFPALTPLYPDRQMVLETKPNHLSTRIMDMMAPVGFGQRGLIVAPPK
ECCCCCHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCC
AGKTMLLKEIANSITTNHPEAELIVLLIDERPEEVTDIERSVAGDVVSSTFDEVPENHIK
CCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPGAFHRPKRFF
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCHHHH
GAARNIEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIR
HHHCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCEECC
RSGTRKEELLVPKEHLDRLWSIRKTMSDTPDFVEKFMRKMKKTKTNQEFFDILIQEWKQA
CCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NMSAARR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]