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The map label for this gene is atpA [H]

Identifier: 52787606

GI number: 52787606

Start: 3754791

End: 3756299

Strand: Reverse

Name: atpA [H]

Synonym: BLi03928

Alternate gene names: 52787606

Gene position: 3756299-3754791 (Counterclockwise)

Preceding gene: 52787607

Following gene: 52787605

Centisome position: 88.96

GC content: 50.43

Gene sequence:

>1509_bases
GTGAGCATCAAAGCTGAAGAAATTAGCACTCTCATAAAACAGCAAATTGAAAACTATCAGTCTGAAATAGAAGTTCACGA
CGTAGGTACGGTAATTCAGGTCGGTGACGGTATCGCACGCGTACACGGCCTTGATAACTGTATGGCAGGTGAGCTTGTCG
AATTTTCAAACGGTGTGCTGGGCTTAGCTCAGAACCTTGAAGAATCAAATGTAGGTATCGTTATTTTGGGACCTTACAAA
GACATCCGTGAAGGTGACGAAGTTAAAAGAACCGGCCGGATCATGGAAGTCCCTGTCGGCGAAGAGCTGCTCGGCCGCGT
TGTCAACCCGCTCGGCCAGCCTGTTGACGGAATGGGCCCGGTTCTCACAAGCAAAACCCGTCCGATCGAAAGCCCGGCTC
CTGGAGTTATGGATCGTAAATCCGTACACGAGCCGCTTCAAACGGGGATCAAATCAATCGATGCTTTAATTCCGATCGGC
CGCGGCCAGCGTGAGCTGATTATCGGTGACCGTCAAACGGGTAAAACGTCGATTGCGATCGATACAATTCTGAATCAGAA
AGACCAGGATATGATTTGTATCTATGTCGCGATCGGTCAGAAAGAATCGACAGTCCGCGGCGTTGTCGAAACGCTTCGCA
AACACGGCGCCCTTGACTATACGATCGTTGTGACGGCTTCCGCTTCACAGCCTGCCCCTCTATTGTACCTCGCGCCGTAT
GCAGGGGTTGCGATGGGAGAGGAATTCATGTACAACGGCAAGCACGTGCTGGTTGTGTATGACGACCTTTCAAAACAGGC
TACCGCATATCGTGAACTGTCCTTGCTTCTTCGCCGTCCTCCTGGTCGTGAAGCATTCCCTGGGGATGTATTCTATCTTC
ACTCCCGTTTGCTTGAACGCGCTGCAAAATTGAGCGACGCCAAAGGCGGAGGATCTTTAACGGCACTTCCGTTCGTTGAA
ACGCAAGCAGGCGACATTTCGGCGTACATTCCGACAAACGTCATTTCGATCACTGACGGACAAATCTTCCTGCAGTCTGA
TTTGTTCTTCTCTGGCGTGCGTCCTGCGGTCAACCCGGGATTGTCTGTATCCCGTGTCGGCGGGTCCGCGCAAATCAAAG
CGATGAAGAAAGTTGCCGGTACGCTGCGCCTTGATTTGGCATCATACCGTGAGCTTGAAGCATTCGCACAATTCGGCTCA
GATTTGGATAAAGCGACACAGGCGAAGCTGAATCGCGGTGCCCGTACGGTTGAAGTACTTAAACAGGATCTGCACAAACC
GCTTCGCGTTGAAAAGCAGGTTGCGATTCTCTATGCTCTGACAAGAGGCTTCCTTGATGATGTGCCTGTTGAGGATATCA
AACGTTTTGAAGAAGAGCTCTTTATGTATCTTGACCAAAATCATAAAGATCTGCTCGATTCAATCGCCCAGACAGGAAAC
CTTCCTGCCGATGAGGACATGAAGGGTGCAATCGAAGGCTTTAAACGTACGTTCGCGCCAAGCAACTAA

Upstream 100 bases:

>100_bases
CGCATCGGGAACCGCATTTATGACGGCAGTGTAAGAGGAAAGCTTGACCGGATAGAACGTCAATTAGCAGGCGAAAATCG
AAAGAAGGGGTGAAACCTAA

Downstream 100 bases:

>100_bases
ACAATAAAAAGTGAGAAAAAGGCTATCTTTTTCTCTCTTTTTCACGTCAATGCGAAGGAATTTGAAAACAAAAAGGTGGT
GAAACCTTTTGGCCTCATTA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSIKAEEISTLIKQQIENYQSEIEVHDVGTVIQVGDGIARVHGLDNCMAGELVEFSNGVLGLAQNLEESNVGIVILGPYK
DIREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPVDGMGPVLTSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDALIPIG
RGQRELIIGDRQTGKTSIAIDTILNQKDQDMICIYVAIGQKESTVRGVVETLRKHGALDYTIVVTASASQPAPLLYLAPY
AGVAMGEEFMYNGKHVLVVYDDLSKQATAYRELSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFVE
TQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAVNPGLSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFAQFGS
DLDKATQAKLNRGARTVEVLKQDLHKPLRVEKQVAILYALTRGFLDDVPVEDIKRFEEELFMYLDQNHKDLLDSIAQTGN
LPADEDMKGAIEGFKRTFAPSN

Sequences:

>Translated_502_residues
MSIKAEEISTLIKQQIENYQSEIEVHDVGTVIQVGDGIARVHGLDNCMAGELVEFSNGVLGLAQNLEESNVGIVILGPYK
DIREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPVDGMGPVLTSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDALIPIG
RGQRELIIGDRQTGKTSIAIDTILNQKDQDMICIYVAIGQKESTVRGVVETLRKHGALDYTIVVTASASQPAPLLYLAPY
AGVAMGEEFMYNGKHVLVVYDDLSKQATAYRELSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFVE
TQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAVNPGLSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFAQFGS
DLDKATQAKLNRGARTVEVLKQDLHKPLRVEKQVAILYALTRGFLDDVPVEDIKRFEEELFMYLDQNHKDLLDSIAQTGN
LPADEDMKGAIEGFKRTFAPSN
>Mature_501_residues
SIKAEEISTLIKQQIENYQSEIEVHDVGTVIQVGDGIARVHGLDNCMAGELVEFSNGVLGLAQNLEESNVGIVILGPYKD
IREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPVDGMGPVLTSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDALIPIGR
GQRELIIGDRQTGKTSIAIDTILNQKDQDMICIYVAIGQKESTVRGVVETLRKHGALDYTIVVTASASQPAPLLYLAPYA
GVAMGEEFMYNGKHVLVVYDDLSKQATAYRELSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFVET
QAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAVNPGLSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFAQFGSD
LDKATQAKLNRGARTVEVLKQDLHKPLRVEKQVAILYALTRGFLDDVPVEDIKRFEEELFMYLDQNHKDLLDSIAQTGNL
PADEDMKGAIEGFKRTFAPSN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=490, Percent_Identity=60, Blast_Score=603, Evalue=1e-173,
Organism=Homo sapiens, GI4757810, Length=490, Percent_Identity=60, Blast_Score=603, Evalue=1e-173,
Organism=Homo sapiens, GI19913428, Length=307, Percent_Identity=29.3159609120521, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=390, Percent_Identity=29.2307692307692, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=26.2658227848101, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=27.7566539923954, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790172, Length=510, Percent_Identity=56.8627450980392, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1788251, Length=323, Percent_Identity=30.9597523219814, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790170, Length=349, Percent_Identity=26.647564469914, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=58.1349206349206, Blast_Score=606, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=58.1349206349206, Blast_Score=604, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=53.5714285714286, Blast_Score=548, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI17510931, Length=464, Percent_Identity=26.0775862068966, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=28.8590604026846, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=432, Percent_Identity=23.1481481481481, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=64, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=42.4657534246575, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=259, Percent_Identity=27.4131274131274, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=509, Percent_Identity=57.5638506876228, Blast_Score=597, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6319603, Length=304, Percent_Identity=27.6315789473684, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=412, Percent_Identity=26.2135922330097, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=58.019801980198, Blast_Score=598, Evalue=1e-171,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=29.2358803986711, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=29.2358803986711, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=29.2358803986711, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24638766, Length=412, Percent_Identity=25.4854368932039, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28574560, Length=416, Percent_Identity=25.9615384615385, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583992, Length=263, Percent_Identity=26.2357414448669, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583988, Length=263, Percent_Identity=26.2357414448669, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583986, Length=263, Percent_Identity=26.2357414448669, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583984, Length=263, Percent_Identity=26.2357414448669, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129479, Length=263, Percent_Identity=27.7566539923954, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54724; Mature: 54593

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKAEEISTLIKQQIENYQSEIEVHDVGTVIQVGDGIARVHGLDNCMAGELVEFSNGVL
CCCCHHHHHHHHHHHHHHHHHHEEHHHCCCEEEECCCHHHHHCCCCHHHHHHHHHCCCHH
GLAQNLEESNVGIVILGPYKDIREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPVDGMGP
HHHHCCCCCCCCEEEECCCHHHHCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
VLTSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDALIPIGRGQRELIIGDRQTGKTSIAI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEH
DTILNQKDQDMICIYVAIGQKESTVRGVVETLRKHGALDYTIVVTASASQPAPLLYLAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCC
AGVAMGEEFMYNGKHVLVVYDDLSKQATAYRELSLLLRRPPGREAFPGDVFYLHSRLLER
CCHHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDAKGGGSLTALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAVNPG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCCCCCCC
LSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
KQDLHKPLRVEKQVAILYALTRGFLDDVPVEDIKRFEEELFMYLDQNHKDLLDSIAQTGN
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPADEDMKGAIEGFKRTFAPSN
CCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIKAEEISTLIKQQIENYQSEIEVHDVGTVIQVGDGIARVHGLDNCMAGELVEFSNGVL
CCCHHHHHHHHHHHHHHHHHHEEHHHCCCEEEECCCHHHHHCCCCHHHHHHHHHCCCHH
GLAQNLEESNVGIVILGPYKDIREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPVDGMGP
HHHHCCCCCCCCEEEECCCHHHHCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
VLTSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDALIPIGRGQRELIIGDRQTGKTSIAI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEH
DTILNQKDQDMICIYVAIGQKESTVRGVVETLRKHGALDYTIVVTASASQPAPLLYLAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCC
AGVAMGEEFMYNGKHVLVVYDDLSKQATAYRELSLLLRRPPGREAFPGDVFYLHSRLLER
CCHHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDAKGGGSLTALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAVNPG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCCCCCCC
LSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
KQDLHKPLRVEKQVAILYALTRGFLDDVPVEDIKRFEEELFMYLDQNHKDLLDSIAQTGN
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPADEDMKGAIEGFKRTFAPSN
CCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA