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The map label for this gene is dhbC [H]

Identifier: 52787579

GI number: 52787579

Start: 3727899

End: 3729092

Strand: Reverse

Name: dhbC [H]

Synonym: BLi03901

Alternate gene names: 52787579

Gene position: 3729092-3727899 (Counterclockwise)

Preceding gene: 52787580

Following gene: 52787578

Centisome position: 88.31

GC content: 54.94

Gene sequence:

>1194_bases
ATGATGATAGAACGTCATGTCGTGTCAGAAGCGCTTGCAGATCAGCTGTTAAAGGAATATCAGGCCGGTGCTTCATTCTT
TTTCTCTTCCCCTGAGCGGACCATTCTGGCGGAAGGTGTTTTTGCTTCTGTTTCTCAAACCGAAGAGCAAAGCCTTGCTC
AGCGGACTGCGGAAGTTCTGAAAAAAGCCAGGGAGAACGGGCAGGAAAATCCGATTGTAGTTGGAGCTGTGCCATTTGAC
GATGCAAAGCCGGCGCAGTTAACCGTGCCGGTCGAAGCGTGGCATGCGGGGCCGCTGACATGTGAAGAAGACGATAAAGA
GGTGCCTGAACCTGCCCTGCACCCCTATGATGTCCAGCAGATTCCAAGCCCGGAAGCGTATATGGCCGGAGTCAGACAAG
GATTGGCAGGTATAGCAGCAGGAGAATACAGCAAGATCGTCCTTTCCCGGTCATTGCAGCTGACCTCGCCGATCAAAGTC
GATATCGGTCAATTGCTGCGAAATCTTGCCCGCCGCAATACAAGCGGGTACAACTTTGCCGTTGATTTAACCGGGCAGTC
ATCTGAAGCGCCTCGCACCACTTTGATAGGCGCGAGTCCCGAACTGCTTGTATCACGGTCCGGGTTCTGCGTTACGGCAA
ATCCTTTAGCAGGTTCAAGACCTCGGAGCGATGATCCCGAAGAAGATCGAAGACGGGCGGCTGAACTGCTTGCTTCGCCT
AAAGACCGTCACGAACATGCGGTCGTTGTCGAAGCGGTTGCTTCCGCGCTCAGGCCGTTTTGCCGGAAGCTGGAGGTGCC
GGAACCGTCGCTCATCAGCACGCCGACGATGTGGCATCTTTCAACGGAATTGAAGGGAGAGCTTACAGACCTCTCTGTAT
CATCATTGGAGCTTGCCGCCGCCCTTCATCCGACGCCCGCTGTCTGCGGCACGCCGACGAATGCGGCGAAAGAAGCGATT
AAACAGATTGAGCCGTTTGACCGCGGGTTTTTCACAGGTATGGTCGGCTGGTGCGACGCGGACGGTGACGGAGAATGGGT
TGTAACGATTCGCTGTGCCGAGGCGGAGGAACACGCGCTTCGACTGTACGCAGGTGCCGGAATTGTCGCCGGGTCGAAGC
CTGAAGACGAACTTGCCGAAACGTCTGCAAAGTTTCGGACAATGCTTCTTGCGATGGGAATGAACAGTGAGTAA

Upstream 100 bases:

>100_bases
ATTTTTGCTGTCTGACGGGGCTCGTCATATTACGATGCACGATTTGCGCGTCGATGGCGGAGCAACGCTTGGAGCCTGAT
TCAATCTAAAGGAGGTTTTG

Downstream 100 bases:

>100_bases
CGGAGGGATAGAGATGCTGAAAGGATGCACGACATGGCCGAAGGAGTTTGCGGATAAATATCGGAAGGAGGGATGCTGGC
GAGGCGAAACTTTTGGAAAA

Product: isochorismate synthase DhbC

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MMIERHVVSEALADQLLKEYQAGASFFFSSPERTILAEGVFASVSQTEEQSLAQRTAEVLKKARENGQENPIVVGAVPFD
DAKPAQLTVPVEAWHAGPLTCEEDDKEVPEPALHPYDVQQIPSPEAYMAGVRQGLAGIAAGEYSKIVLSRSLQLTSPIKV
DIGQLLRNLARRNTSGYNFAVDLTGQSSEAPRTTLIGASPELLVSRSGFCVTANPLAGSRPRSDDPEEDRRRAAELLASP
KDRHEHAVVVEAVASALRPFCRKLEVPEPSLISTPTMWHLSTELKGELTDLSVSSLELAAALHPTPAVCGTPTNAAKEAI
KQIEPFDRGFFTGMVGWCDADGDGEWVVTIRCAEAEEHALRLYAGAGIVAGSKPEDELAETSAKFRTMLLAMGMNSE

Sequences:

>Translated_397_residues
MMIERHVVSEALADQLLKEYQAGASFFFSSPERTILAEGVFASVSQTEEQSLAQRTAEVLKKARENGQENPIVVGAVPFD
DAKPAQLTVPVEAWHAGPLTCEEDDKEVPEPALHPYDVQQIPSPEAYMAGVRQGLAGIAAGEYSKIVLSRSLQLTSPIKV
DIGQLLRNLARRNTSGYNFAVDLTGQSSEAPRTTLIGASPELLVSRSGFCVTANPLAGSRPRSDDPEEDRRRAAELLASP
KDRHEHAVVVEAVASALRPFCRKLEVPEPSLISTPTMWHLSTELKGELTDLSVSSLELAAALHPTPAVCGTPTNAAKEAI
KQIEPFDRGFFTGMVGWCDADGDGEWVVTIRCAEAEEHALRLYAGAGIVAGSKPEDELAETSAKFRTMLLAMGMNSE
>Mature_397_residues
MMIERHVVSEALADQLLKEYQAGASFFFSSPERTILAEGVFASVSQTEEQSLAQRTAEVLKKARENGQENPIVVGAVPFD
DAKPAQLTVPVEAWHAGPLTCEEDDKEVPEPALHPYDVQQIPSPEAYMAGVRQGLAGIAAGEYSKIVLSRSLQLTSPIKV
DIGQLLRNLARRNTSGYNFAVDLTGQSSEAPRTTLIGASPELLVSRSGFCVTANPLAGSRPRSDDPEEDRRRAAELLASP
KDRHEHAVVVEAVASALRPFCRKLEVPEPSLISTPTMWHLSTELKGELTDLSVSSLELAAALHPTPAVCGTPTNAAKEAI
KQIEPFDRGFFTGMVGWCDADGDGEWVVTIRCAEAEEHALRLYAGAGIVAGSKPEDELAETSAKFRTMLLAMGMNSE

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=381, Percent_Identity=40.4199475065617, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI87082077, Length=286, Percent_Identity=29.020979020979, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1788114, Length=198, Percent_Identity=28.7878787878788, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787518, Length=286, Percent_Identity=29.3706293706294, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=292, Percent_Identity=28.0821917808219, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 42817; Mature: 42817

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIERHVVSEALADQLLKEYQAGASFFFSSPERTILAEGVFASVSQTEEQSLAQRTAEVL
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
KKARENGQENPIVVGAVPFDDAKPAQLTVPVEAWHAGPLTCEEDDKEVPEPALHPYDVQQ
HHHHHCCCCCCEEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
IPSPEAYMAGVRQGLAGIAAGEYSKIVLSRSLQLTSPIKVDIGQLLRNLARRNTSGYNFA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
VDLTGQSSEAPRTTLIGASPELLVSRSGFCVTANPLAGSRPRSDDPEEDRRRAAELLASP
EEECCCCCCCCCEEEECCCCHHEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCC
KDRHEHAVVVEAVASALRPFCRKLEVPEPSLISTPTMWHLSTELKGELTDLSVSSLELAA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHCCCCCCCCCHHHHHHHH
ALHPTPAVCGTPTNAAKEAIKQIEPFDRGFFTGMVGWCDADGDGEWVVTIRCAEAEEHAL
HCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCEEECCCCCCCEEEEEEECCCCCCEE
RLYAGAGIVAGSKPEDELAETSAKFRTMLLAMGMNSE
EEEECCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMIERHVVSEALADQLLKEYQAGASFFFSSPERTILAEGVFASVSQTEEQSLAQRTAEVL
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
KKARENGQENPIVVGAVPFDDAKPAQLTVPVEAWHAGPLTCEEDDKEVPEPALHPYDVQQ
HHHHHCCCCCCEEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
IPSPEAYMAGVRQGLAGIAAGEYSKIVLSRSLQLTSPIKVDIGQLLRNLARRNTSGYNFA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
VDLTGQSSEAPRTTLIGASPELLVSRSGFCVTANPLAGSRPRSDDPEEDRRRAAELLASP
EEECCCCCCCCCEEEECCCCHHEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCC
KDRHEHAVVVEAVASALRPFCRKLEVPEPSLISTPTMWHLSTELKGELTDLSVSSLELAA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHCCCCCCCCCHHHHHHHH
ALHPTPAVCGTPTNAAKEAIKQIEPFDRGFFTGMVGWCDADGDGEWVVTIRCAEAEEHAL
HCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCEEECCCCCCCEEEEEEECCCCCCEE
RLYAGAGIVAGSKPEDELAETSAKFRTMLLAMGMNSE
EEEECCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]