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The map label for this gene is bdbC [H]

Identifier: 52787227

GI number: 52787227

Start: 3378741

End: 3379154

Strand: Reverse

Name: bdbC [H]

Synonym: BLi03537

Alternate gene names: 52787227

Gene position: 3379154-3378741 (Counterclockwise)

Preceding gene: 52787228

Following gene: 52787226

Centisome position: 80.02

GC content: 46.38

Gene sequence:

>414_bases
ATGAAAAATAAACTGCTTTTTCTGTACGGCGCCTGGATCGTCTCATTAACGGCGACGCTAGGCAGCTTGTACTTCAGCGA
AATCCGCAAATTTATTCCTTGCGAACTGTGCTGGTATCAGCGGATTATGATGTATCCGCTCGTGCTGATTCTCGGAATTG
CGACATTTCAGGGCGATGCCCGCGTGAAAAAATACGTGCTGCCGATGGCGGTGATCGGCGCAGGCATTTCCCTGATGCAC
TACATGGAACAAAAAATTCCCGGATTCAACGGCATTAAACCGTGTGTCACAGGAGTGCCTTGCTCAGGGCAGTATATCAA
TTGGTTCGGTTTCATCACGATTCCGTTTCTCGCCCTTATTGCATTTATTTTGATTATCATTTTTATGTGCTTTCTCAAGG
GGAAAGACGAGTAA

Upstream 100 bases:

>100_bases
TCGACGCCGACGATCTTTGTCAACGGCGTAAAAATCGACAAACCGTTTGATTATGACAAAATCAAAGAAACGATCGAGAA
AGAGCTGAAAGGCCAGTCTG

Downstream 100 bases:

>100_bases
AAAGAGCATTGTCTGACAATGCTCTTTTTTTATTTCTTATACATGTTCAATAGAAAGGATGTTATAATATTTGGAAATTA
TCAAATAGATGTGAAGGATG

Product: BdbC

Products: NA

Alternate protein names: Disulfide oxidoreductase C; Thiol-disulfide oxidoreductase C [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKNKLLFLYGAWIVSLTATLGSLYFSEIRKFIPCELCWYQRIMMYPLVLILGIATFQGDARVKKYVLPMAVIGAGISLMH
YMEQKIPGFNGIKPCVTGVPCSGQYINWFGFITIPFLALIAFILIIIFMCFLKGKDE

Sequences:

>Translated_137_residues
MKNKLLFLYGAWIVSLTATLGSLYFSEIRKFIPCELCWYQRIMMYPLVLILGIATFQGDARVKKYVLPMAVIGAGISLMH
YMEQKIPGFNGIKPCVTGVPCSGQYINWFGFITIPFLALIAFILIIIFMCFLKGKDE
>Mature_137_residues
MKNKLLFLYGAWIVSLTATLGSLYFSEIRKFIPCELCWYQRIMMYPLVLILGIATFQGDARVKKYVLPMAVIGAGISLMH
YMEQKIPGFNGIKPCVTGVPCSGQYINWFGFITIPFLALIAFILIIIFMCFLKGKDE

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168, although it can partially substitute for BdbB when the

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family. BdbC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR012187 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 15548; Mature: 15548

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLLFLYGAWIVSLTATLGSLYFSEIRKFIPCELCWYQRIMMYPLVLILGIATFQGDA
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
RVKKYVLPMAVIGAGISLMHYMEQKIPGFNGIKPCVTGVPCSGQYINWFGFITIPFLALI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHH
AFILIIIFMCFLKGKDE
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNKLLFLYGAWIVSLTATLGSLYFSEIRKFIPCELCWYQRIMMYPLVLILGIATFQGDA
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
RVKKYVLPMAVIGAGISLMHYMEQKIPGFNGIKPCVTGVPCSGQYINWFGFITIPFLALI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHH
AFILIIIFMCFLKGKDE
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 10455116; 11844773; 11744713; 11872755 [H]