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The map label for this gene is yfhA [H]

Identifier: 52787164

GI number: 52787164

Start: 3313500

End: 3314555

Strand: Reverse

Name: yfhA [H]

Synonym: BLi03473

Alternate gene names: 52787164

Gene position: 3314555-3313500 (Counterclockwise)

Preceding gene: 52787165

Following gene: 52787163

Centisome position: 78.49

GC content: 53.12

Gene sequence:

>1056_bases
ATGAAAAATTACCGCACGCTGAGAATCGGAAAAGGCGGCATTTCATTGTTGATCGGCAGAAAAGCGCTGTTTTCATTCGT
GATCCTATTGGTGTTGACGGCTTGTGCAGTCATCCTCAGCGCCGGCATCGGCGAACGTTTTATTTCTCCGGGCGCCGTCG
CGAAAACGTTTTTGGGCATGGGGGATCCGGGCGATGACCTGATCATCATGTCCTTCAGGATGCCGCGGATTTTGGTTGCT
CTGTTTGCCGGAATCTGTCTGGCGGCAGCCGGATCGATCCTCCAGGGTCTGATCCGCAATCCGCTCGCTTCGCCGGATAT
TATCGGTGTGACCGGCGGGGCTTCAGTCGCCGTTGTCTTGTTTTTAATGCTGTTTTCCAATAAAAATAATGCGCTTACGG
TCAGCATCAGCTGGCTCCCGGTCGCCGCTTTTATCGGCGCGGCTCTCGCCGGAATGCTCGTTTATTTTCTTTCATATAAA
AACGGCTCTTCAACTTTCAGGCTCGTTTTGATCGGAATCGGATTTTCGATGCTTGCCCAGTCGCTGACGACATTGTTTAT
GATAAAAGGACCGATATACAGAATGTCCCAGGCGAACGTCTGGATTACCGGATCAGTATATGGCTCCAACTGGCAGGATG
TGAACGTTTTATTGCCGGCTGCGCTTGTCCTTTTGCTGATATCGGCAGCCGCCGCCAGAAACGTCAATATCCAGACGCTC
GGCGAAGAACTGGCGACAGGAGCGGGCAGCTCGGTTCAGCGAAACCGCTTTTTGCTCCTGCTTCTGAGCACTGCTTTTGC
CGGAATCGCCGTTGCTTTTGCCGGAACTGTCGGTTTTGTCGGTTTGATGGCCCCGCATATCGCAAGAAGGCTTGTCGGAT
CGTCATTCGGCGCCCTCTTGCCGGTTGCCGCGCTGATCGGAGGATTGCTCGTGCTGATTGCCGACATCATCGGCCGCACG
CTTTTTTCTCCCGTTGAAGTGCCTGCCGGTGTGTTTACCGCCGCGATCGGCGCCCCTTACTTTATCTACTTGCTGTATAA
AAGCAGAAACCAATAA

Upstream 100 bases:

>100_bases
CAAGGTACCTGATCATGCCTGAAGAAGTACCTGTCGGCGTCATGACAGCCATCATTGGGACACCCATTTTTGTCTATATC
GCGAGAAGGGGGTTCCAAAA

Downstream 100 bases:

>100_bases
AAGGAGAGATTTCATTTATGAGTGCCATTTCAACAGAAACGTTAAGCTTAGGTTATGGAGAAACAATCATTATTGATGAG
TTAAACTTAACGATCCCAAA

Product: YfhA

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKNYRTLRIGKGGISLLIGRKALFSFVILLVLTACAVILSAGIGERFISPGAVAKTFLGMGDPGDDLIIMSFRMPRILVA
LFAGICLAAAGSILQGLIRNPLASPDIIGVTGGASVAVVLFLMLFSNKNNALTVSISWLPVAAFIGAALAGMLVYFLSYK
NGSSTFRLVLIGIGFSMLAQSLTTLFMIKGPIYRMSQANVWITGSVYGSNWQDVNVLLPAALVLLLISAAAARNVNIQTL
GEELATGAGSSVQRNRFLLLLLSTAFAGIAVAFAGTVGFVGLMAPHIARRLVGSSFGALLPVAALIGGLLVLIADIIGRT
LFSPVEVPAGVFTAAIGAPYFIYLLYKSRNQ

Sequences:

>Translated_351_residues
MKNYRTLRIGKGGISLLIGRKALFSFVILLVLTACAVILSAGIGERFISPGAVAKTFLGMGDPGDDLIIMSFRMPRILVA
LFAGICLAAAGSILQGLIRNPLASPDIIGVTGGASVAVVLFLMLFSNKNNALTVSISWLPVAAFIGAALAGMLVYFLSYK
NGSSTFRLVLIGIGFSMLAQSLTTLFMIKGPIYRMSQANVWITGSVYGSNWQDVNVLLPAALVLLLISAAAARNVNIQTL
GEELATGAGSSVQRNRFLLLLLSTAFAGIAVAFAGTVGFVGLMAPHIARRLVGSSFGALLPVAALIGGLLVLIADIIGRT
LFSPVEVPAGVFTAAIGAPYFIYLLYKSRNQ
>Mature_351_residues
MKNYRTLRIGKGGISLLIGRKALFSFVILLVLTACAVILSAGIGERFISPGAVAKTFLGMGDPGDDLIIMSFRMPRILVA
LFAGICLAAAGSILQGLIRNPLASPDIIGVTGGASVAVVLFLMLFSNKNNALTVSISWLPVAAFIGAALAGMLVYFLSYK
NGSSTFRLVLIGIGFSMLAQSLTTLFMIKGPIYRMSQANVWITGSVYGSNWQDVNVLLPAALVLLLISAAAARNVNIQTL
GEELATGAGSSVQRNRFLLLLLSTAFAGIAVAFAGTVGFVGLMAPHIARRLVGSSFGALLPVAALIGGLLVLIADIIGRT
LFSPVEVPAGVFTAAIGAPYFIYLLYKSRNQ

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=40.0709219858156, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786804, Length=339, Percent_Identity=32.1533923303835, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=39.0243902439024, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=36.1022364217252, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790741, Length=294, Percent_Identity=32.9931972789116, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788004, Length=309, Percent_Identity=33.6569579288026, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36730; Mature: 36730

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYRTLRIGKGGISLLIGRKALFSFVILLVLTACAVILSAGIGERFISPGAVAKTFLGM
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHCC
GDPGDDLIIMSFRMPRILVALFAGICLAAAGSILQGLIRNPLASPDIIGVTGGASVAVVL
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
FLMLFSNKNNALTVSISWLPVAAFIGAALAGMLVYFLSYKNGSSTFRLVLIGIGFSMLAQ
HHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
SLTTLFMIKGPIYRMSQANVWITGSVYGSNWQDVNVLLPAALVLLLISAAAARNVNIQTL
HHHHHHHHCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
GEELATGAGSSVQRNRFLLLLLSTAFAGIAVAFAGTVGFVGLMAPHIARRLVGSSFGALL
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
PVAALIGGLLVLIADIIGRTLFSPVEVPAGVFTAAIGAPYFIYLLYKSRNQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
>Mature Secondary Structure
MKNYRTLRIGKGGISLLIGRKALFSFVILLVLTACAVILSAGIGERFISPGAVAKTFLGM
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHCC
GDPGDDLIIMSFRMPRILVALFAGICLAAAGSILQGLIRNPLASPDIIGVTGGASVAVVL
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
FLMLFSNKNNALTVSISWLPVAAFIGAALAGMLVYFLSYKNGSSTFRLVLIGIGFSMLAQ
HHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
SLTTLFMIKGPIYRMSQANVWITGSVYGSNWQDVNVLLPAALVLLLISAAAARNVNIQTL
HHHHHHHHCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
GEELATGAGSSVQRNRFLLLLLSTAFAGIAVAFAGTVGFVGLMAPHIARRLVGSSFGALL
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
PVAALIGGLLVLIADIIGRTLFSPVEVPAGVFTAAIGAPYFIYLLYKSRNQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]