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The map label for this gene is yueK [H]

Identifier: 52787058

GI number: 52787058

Start: 3213067

End: 3214536

Strand: Reverse

Name: yueK [H]

Synonym: BLi03363

Alternate gene names: 52787058

Gene position: 3214536-3213067 (Counterclockwise)

Preceding gene: 52787059

Following gene: 52787057

Centisome position: 76.13

GC content: 45.71

Gene sequence:

>1470_bases
TTGGAACACCGTTTTACAGACGACAGTCTAGCACTACACACAGACCTATATCAAATTAATATGGCGGAAACGTATTGGCG
CGACGGCATTGATCAAAAGAAAGCCGTATTTGAACTGTTTTTCAGAAAGCTCCCTTTTGACAGCGGTTTTGCCGTTTTTG
CCGGTCTTGAAAAAGCGATTGAATTTTTGCGGGATTTCAGATTTACTGAAAGCGATTTAGTTTATTTAAAAGAAGAGCTG
GGCTTTAAAGATGACTTTCTCGGCTTTTTAAAAGATATGAGATTCACCGGTTCGCTTTATTCTATGCAGGAAGGCGAAAT
CGTGTTTGGCAACGAACCGATCATGAGGATCGAAGCGCCTTTGGCTGAAGCGCAGCTGATTGAGACGGCTCTGCTCAACA
TTGTGAATTACCAAACATTGATTGCCACAAAAGCGGCGAGAATCAAAAGTGTGATCGGAGAAGAGACGGCGCTTGAATTT
GGAACAAGGCGCGCGCATGAAATGGACGCGGCGATGTGGGGAGCAAGAGCCGCGATTATCGGCGGATTCGACGCGACAAG
CAATGTCCGCGCCGGCAAGCGGTTTGACATTCCGGTATCAGGCACGCACGCCCATGCGCTTGTACAGGCCTATCGCGATG
AGTACACGGCATTTAAAAAATATGCGGAAACCCATAAAAAATGTGTCTTTTTGGTCGATACATATGATACGGTGCGTTCC
GGCATTCCAAATGCGATCAAAGTAGCAAAGGAATTCGGCGATCAAATTGAATTTTCGGGAATCCGCCTGGACAGCGGAGA
CCTCGCCTATTTGTCGAAGAAAGCGAGAGCCATGCTGGATGAAGCCGGATTTACAGATACAAAAGTTGTTGCATCAAGCG
ATCTTGATGAGTACACGATTATGAACCTTAAAGCCCAGGGTGCAAAAATCGACGTCTGGGGCGTGGGCACAAAGCTGATT
ACCGCTTACGACCAGCCGGCTCTCGGCGCGGTTTACAAACTTGTTTCGATCGAAGAAGACGGAAAGATGGCAGACACGAT
TAAAATTTCTTCGAATCCGGAAAAAGTGACGACTCCAGGCTTGAAAAAGGTGTACAGAATCATCAATCAGCTGAACCATC
ATTCAGAAGGCGATTATATCGCTTTGGACTATGAAAAGGTCAATGAACAGGAGCGGCTGAAGATGTTTCACCCCGTTCAT
ACGTTTATCAGCAAGTTTGTGACGAATTTTGATGCGAAAGATCTTCACCAGCCGATCTTTGAAAAAGGCGAGCTTGTCTA
TGAGAATCCGAGCATTCAGGATATTAAGCGGTATGTTCAAGAAAATCTCAGTTTGCTTTGGGAAGAGTATAAGCGGATCA
GCAAGCCCGAAGAATATCCTGTCGATTTAAGCGAAGCTTGCTGGAACAACAAGATGCAGCAAATTCACGAAGCGAAAATC
AAGGCGAAAAAAGGTCTGGATCAAGGTTGA

Upstream 100 bases:

>100_bases
CAGTGGCTAGCTTTAACCCGGACGGACACGACTGGGCTCTTTCTCATTTTGCAAACACCCTGGGAGCCTCAGTGTCAGAT
TGAGGAAGGAGAAATGAAGG

Downstream 100 bases:

>100_bases
CTCTGTAAACGATAGTTTTTAACATAACTGGGGATTGAAACAGATAATTTCTTCGGGGATTATCTGTTTTTCAATATTAA
GTTCAAATTTGGGTGAATTT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MEHRFTDDSLALHTDLYQINMAETYWRDGIDQKKAVFELFFRKLPFDSGFAVFAGLEKAIEFLRDFRFTESDLVYLKEEL
GFKDDFLGFLKDMRFTGSLYSMQEGEIVFGNEPIMRIEAPLAEAQLIETALLNIVNYQTLIATKAARIKSVIGEETALEF
GTRRAHEMDAAMWGARAAIIGGFDATSNVRAGKRFDIPVSGTHAHALVQAYRDEYTAFKKYAETHKKCVFLVDTYDTVRS
GIPNAIKVAKEFGDQIEFSGIRLDSGDLAYLSKKARAMLDEAGFTDTKVVASSDLDEYTIMNLKAQGAKIDVWGVGTKLI
TAYDQPALGAVYKLVSIEEDGKMADTIKISSNPEKVTTPGLKKVYRIINQLNHHSEGDYIALDYEKVNEQERLKMFHPVH
TFISKFVTNFDAKDLHQPIFEKGELVYENPSIQDIKRYVQENLSLLWEEYKRISKPEEYPVDLSEACWNNKMQQIHEAKI
KAKKGLDQG

Sequences:

>Translated_489_residues
MEHRFTDDSLALHTDLYQINMAETYWRDGIDQKKAVFELFFRKLPFDSGFAVFAGLEKAIEFLRDFRFTESDLVYLKEEL
GFKDDFLGFLKDMRFTGSLYSMQEGEIVFGNEPIMRIEAPLAEAQLIETALLNIVNYQTLIATKAARIKSVIGEETALEF
GTRRAHEMDAAMWGARAAIIGGFDATSNVRAGKRFDIPVSGTHAHALVQAYRDEYTAFKKYAETHKKCVFLVDTYDTVRS
GIPNAIKVAKEFGDQIEFSGIRLDSGDLAYLSKKARAMLDEAGFTDTKVVASSDLDEYTIMNLKAQGAKIDVWGVGTKLI
TAYDQPALGAVYKLVSIEEDGKMADTIKISSNPEKVTTPGLKKVYRIINQLNHHSEGDYIALDYEKVNEQERLKMFHPVH
TFISKFVTNFDAKDLHQPIFEKGELVYENPSIQDIKRYVQENLSLLWEEYKRISKPEEYPVDLSEACWNNKMQQIHEAKI
KAKKGLDQG
>Mature_489_residues
MEHRFTDDSLALHTDLYQINMAETYWRDGIDQKKAVFELFFRKLPFDSGFAVFAGLEKAIEFLRDFRFTESDLVYLKEEL
GFKDDFLGFLKDMRFTGSLYSMQEGEIVFGNEPIMRIEAPLAEAQLIETALLNIVNYQTLIATKAARIKSVIGEETALEF
GTRRAHEMDAAMWGARAAIIGGFDATSNVRAGKRFDIPVSGTHAHALVQAYRDEYTAFKKYAETHKKCVFLVDTYDTVRS
GIPNAIKVAKEFGDQIEFSGIRLDSGDLAYLSKKARAMLDEAGFTDTKVVASSDLDEYTIMNLKAQGAKIDVWGVGTKLI
TAYDQPALGAVYKLVSIEEDGKMADTIKISSNPEKVTTPGLKKVYRIINQLNHHSEGDYIALDYEKVNEQERLKMFHPVH
TFISKFVTNFDAKDLHQPIFEKGELVYENPSIQDIKRYVQENLSLLWEEYKRISKPEEYPVDLSEACWNNKMQQIHEAKI
KAKKGLDQG

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Homo sapiens, GI194394158, Length=513, Percent_Identity=31.5789473684211, Blast_Score=251, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71997952, Length=529, Percent_Identity=35.3497164461248, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI71997947, Length=524, Percent_Identity=35.4961832061069, Blast_Score=289, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71997955, Length=212, Percent_Identity=43.3962264150943, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24581587, Length=521, Percent_Identity=36.2763915547025, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI161076680, Length=204, Percent_Identity=46.5686274509804, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581595, Length=204, Percent_Identity=46.5686274509804, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28574709, Length=204, Percent_Identity=46.5686274509804, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581593, Length=204, Percent_Identity=46.5686274509804, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581591, Length=204, Percent_Identity=46.5686274509804, Blast_Score=174, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 55589; Mature: 55589

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHRFTDDSLALHTDLYQINMAETYWRDGIDQKKAVFELFFRKLPFDSGFAVFAGLEKAI
CCCCCCCCCEEEEEHHEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFLRDFRFTESDLVYLKEELGFKDDFLGFLKDMRFTGSLYSMQEGEIVFGNEPIMRIEAP
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCCCCCCEEECCCCEEEEECC
LAEAQLIETALLNIVNYQTLIATKAARIKSVIGEETALEFGTRRAHEMDAAMWGARAAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
GGFDATSNVRAGKRFDIPVSGTHAHALVQAYRDEYTAFKKYAETHKKCVFLVDTYDTVRS
ECCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
GIPNAIKVAKEFGDQIEFSGIRLDSGDLAYLSKKARAMLDEAGFTDTKVVASSDLDEYTI
CCCHHHHHHHHHCCCEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEE
MNLKAQGAKIDVWGVGTKLITAYDQPALGAVYKLVSIEEDGKMADTIKISSNPEKVTTPG
EEEEECCCEEEEEECCCEEEEECCCCHHHHHHHHHEECCCCCEEEEEEECCCCCCCCCCH
LKKVYRIINQLNHHSEGDYIALDYEKVNEQERLKMFHPVHTFISKFVTNFDAKDLHQPIF
HHHHHHHHHHHCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EKGELVYENPSIQDIKRYVQENLSLLWEEYKRISKPEEYPVDLSEACWNNKMQQIHEAKI
HCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KAKKGLDQG
HHHCCCCCC
>Mature Secondary Structure
MEHRFTDDSLALHTDLYQINMAETYWRDGIDQKKAVFELFFRKLPFDSGFAVFAGLEKAI
CCCCCCCCCEEEEEHHEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFLRDFRFTESDLVYLKEELGFKDDFLGFLKDMRFTGSLYSMQEGEIVFGNEPIMRIEAP
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCCCCCCEEECCCCEEEEECC
LAEAQLIETALLNIVNYQTLIATKAARIKSVIGEETALEFGTRRAHEMDAAMWGARAAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
GGFDATSNVRAGKRFDIPVSGTHAHALVQAYRDEYTAFKKYAETHKKCVFLVDTYDTVRS
ECCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
GIPNAIKVAKEFGDQIEFSGIRLDSGDLAYLSKKARAMLDEAGFTDTKVVASSDLDEYTI
CCCHHHHHHHHHCCCEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEE
MNLKAQGAKIDVWGVGTKLITAYDQPALGAVYKLVSIEEDGKMADTIKISSNPEKVTTPG
EEEEECCCEEEEEECCCEEEEECCCCHHHHHHHHHEECCCCCEEEEEEECCCCCCCCCCH
LKKVYRIINQLNHHSEGDYIALDYEKVNEQERLKMFHPVHTFISKFVTNFDAKDLHQPIF
HHHHHHHHHHHCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EKGELVYENPSIQDIKRYVQENLSLLWEEYKRISKPEEYPVDLSEACWNNKMQQIHEAKI
HCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KAKKGLDQG
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]