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The map label for this gene is menC [H]

Identifier: 52786942

GI number: 52786942

Start: 3098028

End: 3099137

Strand: Reverse

Name: menC [H]

Synonym: BLi03218

Alternate gene names: 52786942

Gene position: 3099137-3098028 (Counterclockwise)

Preceding gene: 52786943

Following gene: 52786938

Centisome position: 73.39

GC content: 45.5

Gene sequence:

>1110_bases
ATGATTCAAATCAAACAGCTGACATTGTACCATCTCAGCATGCGGCTGAAAAAGCCTTTTAAATCAAGCTTGGAAACCTT
TCAGGATCGCAAGTTTATCATCGTTGAAGCTGCTGATCAAGAAGGTGTGACAGGCTGGGGGGAAGTATCCGCTTTTTCAT
CTCCGTGGTACACCGAAGAAACAACGGAGACATGCTACCACATGCTCAAAGATTTTTTGATTCCGGCTGTGCTGCGCGAA
TCATTCACACACCCTTCCGAAGTGCCCGAGGCGCTTCGCGGATTCAAAGGCAACCGAATGGCAAAGGCCGGCCTTGAAGC
CGCCTTTTGGGACATTTACGCCAGGAAAAAAGGGATCTCTTTAAGAGAGGCGCTGGGCGGAGTAAAAACAGAAGTTCCTG
CCGGAGTCGTCGTCGGTCTTGCCCCATTGGATGATATGCTTCAGGAAATTGAACAATATGTAAAAGAAGGATATCAAAGA
ATAAAAATCAAAATTCAGCCCGGGCAGGATATAGAGCTTTTAAAAGAAATACGCCGGCATTTTCCGAAGGTGCCGCTGAT
GGCAGATGCCAACTCTTCTTATGAATTAAAAGACATCAGCCGGATTAAAGAGCTTGACGCATTTAAATTAATGATGATCG
AACAGCCGCTGGCTGATGATGATATCGTTGACCACCGCCATCTGCAAAAACATATCAAAACATCAATTTGTCTTGACGAA
AGCATCCGTTCGGCTGCTGATGCGCGAAAGGCAATTGAGCTCGGCAGCTGCAAAATTATCAATATAAAGCCGTCCCGAGT
CGGCGGTTTGACAGAAGCTCTGAAAATCCACGACATCTGCAAAGAACATCAAATGCCTGTCTGGTGCGGCGGCATGTTTG
AAACCGGCATTTCAAGAGCCCATAATCTTGCACTGAGTTCTCTTCCGCAGTTTTTGATTCCCGGGGATCTTTCTTCATCC
TCAAGGTATTGGGAAGAGGATATCGTAAAACCGGAAATCCGGATCGAGGGCGGCTATATTCAGGTTCCAACCTTACCGGG
AATGGGATTTGAAGTCGATACTCATATTTTAAGAAAGAATTCATCTAAAATAGACGTTTTTAAGCAGTAA

Upstream 100 bases:

>100_bases
TGCTTCATATAAAGTGCCTAAAGCATTTCATTTTGTCGATAGGCTGCCGAGAAATGCTTCAAATAAACTGATGAGACATA
AATTGTAGAGGGAGAGCGCC

Downstream 100 bases:

>100_bases
AGGCTGTTTTAAACGCCGATTTCCAGATTTTCAAGCTTTGTTAAATAGGCGGCCTCTCATGTATATTAAAGCTGTACATT
ATTCCCTTCTCGTTTGGACC

Product: MenC

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MIQIKQLTLYHLSMRLKKPFKSSLETFQDRKFIIVEAADQEGVTGWGEVSAFSSPWYTEETTETCYHMLKDFLIPAVLRE
SFTHPSEVPEALRGFKGNRMAKAGLEAAFWDIYARKKGISLREALGGVKTEVPAGVVVGLAPLDDMLQEIEQYVKEGYQR
IKIKIQPGQDIELLKEIRRHFPKVPLMADANSSYELKDISRIKELDAFKLMMIEQPLADDDIVDHRHLQKHIKTSICLDE
SIRSAADARKAIELGSCKIINIKPSRVGGLTEALKIHDICKEHQMPVWCGGMFETGISRAHNLALSSLPQFLIPGDLSSS
SRYWEEDIVKPEIRIEGGYIQVPTLPGMGFEVDTHILRKNSSKIDVFKQ

Sequences:

>Translated_369_residues
MIQIKQLTLYHLSMRLKKPFKSSLETFQDRKFIIVEAADQEGVTGWGEVSAFSSPWYTEETTETCYHMLKDFLIPAVLRE
SFTHPSEVPEALRGFKGNRMAKAGLEAAFWDIYARKKGISLREALGGVKTEVPAGVVVGLAPLDDMLQEIEQYVKEGYQR
IKIKIQPGQDIELLKEIRRHFPKVPLMADANSSYELKDISRIKELDAFKLMMIEQPLADDDIVDHRHLQKHIKTSICLDE
SIRSAADARKAIELGSCKIINIKPSRVGGLTEALKIHDICKEHQMPVWCGGMFETGISRAHNLALSSLPQFLIPGDLSSS
SRYWEEDIVKPEIRIEGGYIQVPTLPGMGFEVDTHILRKNSSKIDVFKQ
>Mature_369_residues
MIQIKQLTLYHLSMRLKKPFKSSLETFQDRKFIIVEAADQEGVTGWGEVSAFSSPWYTEETTETCYHMLKDFLIPAVLRE
SFTHPSEVPEALRGFKGNRMAKAGLEAAFWDIYARKKGISLREALGGVKTEVPAGVVVGLAPLDDMLQEIEQYVKEGYQR
IKIKIQPGQDIELLKEIRRHFPKVPLMADANSSYELKDISRIKELDAFKLMMIEQPLADDDIVDHRHLQKHIKTSICLDE
SIRSAADARKAIELGSCKIINIKPSRVGGLTEALKIHDICKEHQMPVWCGGMFETGISRAHNLALSSLPQFLIPGDLSSS
SRYWEEDIVKPEIRIEGGYIQVPTLPGMGFEVDTHILRKNSSKIDVFKQ

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=305, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 41752; Mature: 41752

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIKQLTLYHLSMRLKKPFKSSLETFQDRKFIIVEAADQEGVTGWGEVSAFSSPWYTEE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCH
TTETCYHMLKDFLIPAVLRESFTHPSEVPEALRGFKGNRMAKAGLEAAFWDIYARKKGIS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
LREALGGVKTEVPAGVVVGLAPLDDMLQEIEQYVKEGYQRIKIKIQPGQDIELLKEIRRH
HHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHH
FPKVPLMADANSSYELKDISRIKELDAFKLMMIEQPLADDDIVDHRHLQKHIKTSICLDE
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SIRSAADARKAIELGSCKIINIKPSRVGGLTEALKIHDICKEHQMPVWCGGMFETGISRA
HHHHHHHHHHHHHCCCEEEEEECCHHHCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHH
HNLALSSLPQFLIPGDLSSSSRYWEEDIVKPEIRIEGGYIQVPTLPGMGFEVDTHILRKN
HHHHHHHCCCCEECCCCCCCCCHHHHHCCCCEEEEECCEEEECCCCCCCCCHHHHHHHCC
SSKIDVFKQ
CCCCCCCCC
>Mature Secondary Structure
MIQIKQLTLYHLSMRLKKPFKSSLETFQDRKFIIVEAADQEGVTGWGEVSAFSSPWYTEE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCH
TTETCYHMLKDFLIPAVLRESFTHPSEVPEALRGFKGNRMAKAGLEAAFWDIYARKKGIS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
LREALGGVKTEVPAGVVVGLAPLDDMLQEIEQYVKEGYQRIKIKIQPGQDIELLKEIRRH
HHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHH
FPKVPLMADANSSYELKDISRIKELDAFKLMMIEQPLADDDIVDHRHLQKHIKTSICLDE
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SIRSAADARKAIELGSCKIINIKPSRVGGLTEALKIHDICKEHQMPVWCGGMFETGISRA
HHHHHHHHHHHHHCCCEEEEEECCHHHCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHH
HNLALSSLPQFLIPGDLSSSSRYWEEDIVKPEIRIEGGYIQVPTLPGMGFEVDTHILRKN
HHHHHHHCCCCEECCCCCCCCCHHHHHCCCCEEEEECCEEEECCCCCCCCCHHHHHHHCC
SSKIDVFKQ
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]