Click here to switch to the map view.

The map label for this gene is sstT [H]

Identifier: 52786922

GI number: 52786922

Start: 3082781

End: 3083965

Strand: Direct

Name: sstT [H]

Synonym: BLi03198

Alternate gene names: 52786922

Gene position: 3082781-3083965 (Clockwise)

Preceding gene: 52786921

Following gene: 52786925

Centisome position: 73.01

GC content: 47.51

Gene sequence:

>1185_bases
ATGAAATTTGGATTACTGCCAAGGATCATTACGGCAATTGTTCTTGGTGTTATCGTCGGAAGCTTTGCTCCGCTTTGGTT
CGTCAAAACGGCAGCTACTTTCAATGATATTTTTGGAAGCTTCATTAAATTTGTCATTCCTTTTATTATTATCGCTTTTA
TTATTCCCGGCATCGGACAAATCGGCAGCGGCGCCGGAAAAATCCTCGGCATTACGGCAGGTATCGCCTACACGTCAACC
ATTTTTGCAGGCCTCCTGGCGTACCTTGTCGGTTCAAACCTTCTTCCCGCGATCATTTCCGGCCATCAGCTGCAGGAGTT
TAAAAATCCGGAAGAAGTACTGCAAGCAGGATTTTTCACCATTGAAATGACGCCGTTTATGAGCGTGATGAGCGCACTGA
TTTTTGCTTTCATCATGGGGATCGGCATCGCTTATCTGCCCGGAAAAACATTAAAAAACGCGTTTGATGAATTTCAAACG
ATCGTTGAAAAGCTGATATCATATATTATTATTCCGTTACTGCCTGTTCATATTTTCGGTATTTTCACCAATATGACGTT
CGGCGGTCAGGTGCAGACGATTCTATCCGTATTTGCGAAAGTTTTCGTGATGATTATCGTGCTTCACCTTGTCATACTCT
TGATTCAGTACTCCGTTGCGGGTGCTGCAAACGGCAGAAATCCGCTGTCGCTGTTGAAAATCGTAGCACCGGCATACTTC
ACCGCGCTCGGCACACAATCGTCAGCGGCAACGATTCCCGTTACGCTGAGACAAGTCAGAAAAACGGGGGCAAGCCAAAA
AGTGGCTGACTTCGCCGTTCCGCTCCTGGCCAACATTCATTTGTCAGGAAGCACAATTACACTGACAAGCTGTGCAATGG
GCGTGATGATTCTAAACGGTCAAACGCCGACTTTTTCGGTCATGATGCCGTTCATTTTAATGCTTGGCGTCACAATGGTC
GCAGCGCCCGGTGCACCAGGCGGTGCCGTCATGGCCGCTGCCGGATTGTTGCAGTCGATGCTCGGCTTTAATGAAACTAG
CGTATCGTTGATGATCGCTCTTTACCTTGCCCAGGACAGCTTGGGCACAGCAACGAACGTAACAGGAGACGGCGCTCTCA
CCATGCTGATTCACAGGCTGACTTCCAAAAAAGGAATCGGAAAAGAGGAAAATGTGCCTGCATAA

Upstream 100 bases:

>100_bases
ATTATTATTTGAAAATACAGACTTTTTTTATTTTTAACAAAAGAAATCTTTCATATGTTAATATTATAAAAACATTTGTA
TATTTCAGGAGGACACATCT

Downstream 100 bases:

>100_bases
TACAGAAAAGCCAAGGACGCTATCCGCGCCTTGGCTTTTTTTAATTCGTGGAATTTAATGATACGAGCCTGTATGTTAAA
TGAGTCCGTCCGTCTGACCA

Product: hypothetical protein

Products: orotate [Cytoplasm]; fumarate [Cytoplasm]; malate [Cytoplasm]; Na (I) [Cytoplasm]; succinate [Cytoplasm] [C]

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKFGLLPRIITAIVLGVIVGSFAPLWFVKTAATFNDIFGSFIKFVIPFIIIAFIIPGIGQIGSGAGKILGITAGIAYTST
IFAGLLAYLVGSNLLPAIISGHQLQEFKNPEEVLQAGFFTIEMTPFMSVMSALIFAFIMGIGIAYLPGKTLKNAFDEFQT
IVEKLISYIIIPLLPVHIFGIFTNMTFGGQVQTILSVFAKVFVMIIVLHLVILLIQYSVAGAANGRNPLSLLKIVAPAYF
TALGTQSSAATIPVTLRQVRKTGASQKVADFAVPLLANIHLSGSTITLTSCAMGVMILNGQTPTFSVMMPFILMLGVTMV
AAPGAPGGAVMAAAGLLQSMLGFNETSVSLMIALYLAQDSLGTATNVTGDGALTMLIHRLTSKKGIGKEENVPA

Sequences:

>Translated_394_residues
MKFGLLPRIITAIVLGVIVGSFAPLWFVKTAATFNDIFGSFIKFVIPFIIIAFIIPGIGQIGSGAGKILGITAGIAYTST
IFAGLLAYLVGSNLLPAIISGHQLQEFKNPEEVLQAGFFTIEMTPFMSVMSALIFAFIMGIGIAYLPGKTLKNAFDEFQT
IVEKLISYIIIPLLPVHIFGIFTNMTFGGQVQTILSVFAKVFVMIIVLHLVILLIQYSVAGAANGRNPLSLLKIVAPAYF
TALGTQSSAATIPVTLRQVRKTGASQKVADFAVPLLANIHLSGSTITLTSCAMGVMILNGQTPTFSVMMPFILMLGVTMV
AAPGAPGGAVMAAAGLLQSMLGFNETSVSLMIALYLAQDSLGTATNVTGDGALTMLIHRLTSKKGIGKEENVPA
>Mature_394_residues
MKFGLLPRIITAIVLGVIVGSFAPLWFVKTAATFNDIFGSFIKFVIPFIIIAFIIPGIGQIGSGAGKILGITAGIAYTST
IFAGLLAYLVGSNLLPAIISGHQLQEFKNPEEVLQAGFFTIEMTPFMSVMSALIFAFIMGIGIAYLPGKTLKNAFDEFQT
IVEKLISYIIIPLLPVHIFGIFTNMTFGGQVQTILSVFAKVFVMIIVLHLVILLIQYSVAGAANGRNPLSLLKIVAPAYF
TALGTQSSAATIPVTLRQVRKTGASQKVADFAVPLLANIHLSGSTITLTSCAMGVMILNGQTPTFSVMMPFILMLGVTMV
AAPGAPGGAVMAAAGLLQSMLGFNETSVSLMIALYLAQDSLGTATNVTGDGALTMLIHRLTSKKGIGKEENVPA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=265, Percent_Identity=27.9245283018868, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17537407, Length=444, Percent_Identity=23.6486486486486, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=265, Percent_Identity=26.4150943396226, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983099, Length=265, Percent_Identity=26.4150943396226, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=302, Percent_Identity=24.5033112582781, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 41541; Mature: 41541

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: orotate [Periplasm]; fumarate [Periplasm]; malate [Periplasm]; Na (I) [Periplasm]; succinate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + orotate [Periplasm] = Na (I) [Cytoplasm] + orotate [Cytoplasm] Na (I) [Periplasm] + fumarate [Periplasm] = Na (I) [Cytoplasm] + fumarate [Cytoplasm] Na (I) [Periplasm] + malate [Periplasm] = Na (I) [Cytoplasm] + malate [Cytoplasm] Na

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA