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The map label for this gene is ytiP [H]

Identifier: 52786877

GI number: 52786877

Start: 3033482

End: 3034789

Strand: Direct

Name: ytiP [H]

Synonym: BLi03152

Alternate gene names: 52786877

Gene position: 3033482-3034789 (Clockwise)

Preceding gene: 52786873

Following gene: 52786878

Centisome position: 71.84

GC content: 50.0

Gene sequence:

>1308_bases
ATGTTTAACATAAAAGAAAACCAAACCACAGTCAAAAAAGAAATCCTCGCCGGTATTACAACCTTCTTTACAATGGTTTA
TATCGTCGTGGTCAACCCGAGTATCCTTTCCGGCACAGGCGTCCCGTTTGATCAAGTGTTCACTGCCACAATCATCGCTG
CAGTCGTCGGAACGCTTTGGATGGCGCTTGCCGCCAACTTTCCGATCGCGATTGCACCCGGGATGGGACTGAACGTGTAT
TTTGCAGTGTCAGTCGTCGGCTCATCCAACGGCGAAATTTCTTATCAGACGGCGTTCAGCACAGTCTTCGCGGCCGGCAT
TCTCTTTATTATCTTATCGCTAACACCTCTTAGAAAACAACTGATCGAAGCGATTCCGGCTAATTTAAAATACGGAATTA
CCGCCGGAATCGGATTGTTTATCGCTTTTGTCGGTCTGAGAGGAGCCGGCATCATTACCGCGAACGAAGCCAATTTGGTC
GGACTCGGCAATCTGCACTCGCCCGGAGTGATACTGGCATTAATCGGCTTGGCTTTCTCTGTCGTTTTGATGGTGATGAA
TGTGAGCGGCGCTCTATTTTTCGGTATGATCTTAACCGGGCTGATCGCCTTTTTTACCGGCCAGCTTGAGTTTACCAAAG
GGATTATGTCGATGCCTCATCTGCCGGAAAAACTGATCGTCACAAACCCTTTCGCCGCTTTTGGCGATGTCATCCACTAC
GGCCTTTATTCGGTTGTCTTTTCGTTTCTGCTCGTGACGATTTTTGATACGACAGGAACGATGATCGGTGTCGCTGAGCA
AGCCGGACTCATGAAAAACAACAAACTGCCGAATGCAAGAAAAGCCCTCCTTGCCGATTCTACAGCGACGACAGTCGGTG
CAATGTTCGGGACAAGTCCGACGACCGCCTATATCGAATCATCCGCCGGGGTGGCCGCAGGCGGAAGAACGGGGCTTACG
TCTTTAACAGTCGCTGTGCTTTTCGGCGCGGCCCTGTTTTTCAGCCCGCTTGTCAGTGCGGTCTCCGGAATCGCAGCGAT
TACGTCGCCGGCATTGATCATTGTAGGAAGCATGATGATCGGCGCCGTGACGAACATCCGCTGGAAAGAACTTGACGAAG
CATTTCCGGCCTTTCTCGTCATCTTGACAATGCCGCTGACATCATCTATTGCGACAGGCATTTCCCTCGGGTTTATCGCT
TATCCGATTGTGAAAGCCGCGAAAGGCAAATGGCGCGAGATTCATCCGCTTGTCTTCGTGTTTGCTGTTCTCTTTTTCAT
ACACCTTTTCTTTTTGGAAGGGCATTAA

Upstream 100 bases:

>100_bases
CCCCTTCTTTTTTCAGTTTAGCCAAAAACCCTTGCAAAAACACCCGATAACGAATAATATAGATATTGTTTTGCTATAAT
GTTCGTTATTGGAGGAAATG

Downstream 100 bases:

>100_bases
TCAACTGAACCCCGTCTTATTTAAAAAGACGGGGTTTTTTCAATATGTACTTTTAACTTCATCATCTTCACCACCTTTCT
TTTATTACGTATGAAGAAAG

Product: YtiP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MFNIKENQTTVKKEILAGITTFFTMVYIVVVNPSILSGTGVPFDQVFTATIIAAVVGTLWMALAANFPIAIAPGMGLNVY
FAVSVVGSSNGEISYQTAFSTVFAAGILFIILSLTPLRKQLIEAIPANLKYGITAGIGLFIAFVGLRGAGIITANEANLV
GLGNLHSPGVILALIGLAFSVVLMVMNVSGALFFGMILTGLIAFFTGQLEFTKGIMSMPHLPEKLIVTNPFAAFGDVIHY
GLYSVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKLPNARKALLADSTATTVGAMFGTSPTTAYIESSAGVAAGGRTGLT
SLTVAVLFGAALFFSPLVSAVSGIAAITSPALIIVGSMMIGAVTNIRWKELDEAFPAFLVILTMPLTSSIATGISLGFIA
YPIVKAAKGKWREIHPLVFVFAVLFFIHLFFLEGH

Sequences:

>Translated_435_residues
MFNIKENQTTVKKEILAGITTFFTMVYIVVVNPSILSGTGVPFDQVFTATIIAAVVGTLWMALAANFPIAIAPGMGLNVY
FAVSVVGSSNGEISYQTAFSTVFAAGILFIILSLTPLRKQLIEAIPANLKYGITAGIGLFIAFVGLRGAGIITANEANLV
GLGNLHSPGVILALIGLAFSVVLMVMNVSGALFFGMILTGLIAFFTGQLEFTKGIMSMPHLPEKLIVTNPFAAFGDVIHY
GLYSVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKLPNARKALLADSTATTVGAMFGTSPTTAYIESSAGVAAGGRTGLT
SLTVAVLFGAALFFSPLVSAVSGIAAITSPALIIVGSMMIGAVTNIRWKELDEAFPAFLVILTMPLTSSIATGISLGFIA
YPIVKAAKGKWREIHPLVFVFAVLFFIHLFFLEGH
>Mature_435_residues
MFNIKENQTTVKKEILAGITTFFTMVYIVVVNPSILSGTGVPFDQVFTATIIAAVVGTLWMALAANFPIAIAPGMGLNVY
FAVSVVGSSNGEISYQTAFSTVFAAGILFIILSLTPLRKQLIEAIPANLKYGITAGIGLFIAFVGLRGAGIITANEANLV
GLGNLHSPGVILALIGLAFSVVLMVMNVSGALFFGMILTGLIAFFTGQLEFTKGIMSMPHLPEKLIVTNPFAAFGDVIHY
GLYSVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKLPNARKALLADSTATTVGAMFGTSPTTAYIESSAGVAAGGRTGLT
SLTVAVLFGAALFFSPLVSAVSGIAAITSPALIIVGSMMIGAVTNIRWKELDEAFPAFLVILTMPLTSSIATGISLGFIA
YPIVKAAKGKWREIHPLVFVFAVLFFIHLFFLEGH

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=434, Percent_Identity=41.705069124424, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1790150, Length=436, Percent_Identity=40.8256880733945, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI1790499, Length=433, Percent_Identity=35.3348729792148, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI48994909, Length=422, Percent_Identity=33.8862559241706, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45703; Mature: 45703

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNIKENQTTVKKEILAGITTFFTMVYIVVVNPSILSGTGVPFDQVFTATIIAAVVGTLW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MALAANFPIAIAPGMGLNVYFAVSVVGSSNGEISYQTAFSTVFAAGILFIILSLTPLRKQ
HHHHCCCCEEEECCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHH
LIEAIPANLKYGITAGIGLFIAFVGLRGAGIITANEANLVGLGNLHSPGVILALIGLAFS
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHH
VVLMVMNVSGALFFGMILTGLIAFFTGQLEFTKGIMSMPHLPEKLIVTNPFAAFGDVIHY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHEEECCHHHHHHHHHH
GLYSVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKLPNARKALLADSTATTVGAMFGTSP
HHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCC
TTAYIESSAGVAAGGRTGLTSLTVAVLFGAALFFSPLVSAVSGIAAITSPALIIVGSMMI
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GAVTNIRWKELDEAFPAFLVILTMPLTSSIATGISLGFIAYPIVKAAKGKWREIHPLVFV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FAVLFFIHLFFLEGH
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MFNIKENQTTVKKEILAGITTFFTMVYIVVVNPSILSGTGVPFDQVFTATIIAAVVGTLW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MALAANFPIAIAPGMGLNVYFAVSVVGSSNGEISYQTAFSTVFAAGILFIILSLTPLRKQ
HHHHCCCCEEEECCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHH
LIEAIPANLKYGITAGIGLFIAFVGLRGAGIITANEANLVGLGNLHSPGVILALIGLAFS
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHH
VVLMVMNVSGALFFGMILTGLIAFFTGQLEFTKGIMSMPHLPEKLIVTNPFAAFGDVIHY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHEEECCHHHHHHHHHH
GLYSVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKLPNARKALLADSTATTVGAMFGTSP
HHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCC
TTAYIESSAGVAAGGRTGLTSLTVAVLFGAALFFSPLVSAVSGIAAITSPALIIVGSMMI
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GAVTNIRWKELDEAFPAFLVILTMPLTSSIATGISLGFIAYPIVKAAKGKWREIHPLVFV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FAVLFFIHLFFLEGH
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 11591660 [H]