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The map label for this gene is hisJ [H]

Identifier: 52786832

GI number: 52786832

Start: 2991567

End: 2992379

Strand: Direct

Name: hisJ [H]

Synonym: BLi03106

Alternate gene names: 52786832

Gene position: 2991567-2992379 (Clockwise)

Preceding gene: 52786830

Following gene: 52786834

Centisome position: 70.85

GC content: 46.49

Gene sequence:

>813_bases
ATGCTGAAACGAGACGGTCATGTTCATTCTCCCTTTTGTCCGCACGGATCAAAAGACGAATTCAGATATTATATAGAAGA
ATTGTGCAAAAAAGGCTTCCAATCCGTATCCTTTACTGAGCACGCGCCGCTTCCGCCTTCATTTATTGATCCGACTCCGG
AGAAAGACAGCGCCATGCCGATCTCCCAGCTGGGCCGCTATATTGAACGGCTGACCGAACTGAAGGAAGAATACAGAGGA
CAGCTTGACATTTTGATCGGTCTTGAAGTCGATTATATCCGCGCCTTTGAACATGAAACGAAAGCTTTTCTCGATCAGTA
CGGCACACATCTTGACGACAGCATCCTGTCCGTTCATTTTTTGCCGGCTGGATCTTCATACATCTGTCTTGACTACGATG
AAAAAGCGTTTCAGCAGCTGATCGACTGCTACGGCAGCACAGAGCAGGTTTATCTCGCCTATTATGACGAAATCTATTCT
TCCATTGTATCACCGTTGGGAGCATTTAAGCCAAAACGAATCGGCCACATCACGCTTGCGAAAAAATTTGTGAAGCTGTT
TCCGTATACGATGTCGGAAAGCGTTAGAAAATCGGTCTCCTCCTGTCTGGATGAAGCCGCAAAACGCGGACTTGAACTTG
ACTTTAATACGGCCGGCCTCCGCAAGCCTTATGCAGGCAACGTCTATATGGAAGAATGGATGATAAAAGAAGCGGAACAA
AAAAACATCCCGCTTGTCTTTGGGTCTGACGCCCACCAAGCAGAGGATGCCGGATTTGGTTACGAACATTTTGAGAGCCG
CTTTGTTAAATAA

Upstream 100 bases:

>100_bases
TGTTCTTATGATACCATGTAACCAACATTTTTTGAGCAGAATTTTTAATTTTTTTACATCAAAGTGACAACATCTGACTA
TTTTTTTACGGGGTGACATC

Downstream 100 bases:

>100_bases
CGGCGGCTTGCCGACGCTCTCTGTACAACAGACTGAGAAGCCATGTTTTGACTTCCTTGTAATACGCCTGATAAAAGTAC
GGCTCGTGCGGCTGTACATA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLKRDGHVHSPFCPHGSKDEFRYYIEELCKKGFQSVSFTEHAPLPPSFIDPTPEKDSAMPISQLGRYIERLTELKEEYRG
QLDILIGLEVDYIRAFEHETKAFLDQYGTHLDDSILSVHFLPAGSSYICLDYDEKAFQQLIDCYGSTEQVYLAYYDEIYS
SIVSPLGAFKPKRIGHITLAKKFVKLFPYTMSESVRKSVSSCLDEAAKRGLELDFNTAGLRKPYAGNVYMEEWMIKEAEQ
KNIPLVFGSDAHQAEDAGFGYEHFESRFVK

Sequences:

>Translated_270_residues
MLKRDGHVHSPFCPHGSKDEFRYYIEELCKKGFQSVSFTEHAPLPPSFIDPTPEKDSAMPISQLGRYIERLTELKEEYRG
QLDILIGLEVDYIRAFEHETKAFLDQYGTHLDDSILSVHFLPAGSSYICLDYDEKAFQQLIDCYGSTEQVYLAYYDEIYS
SIVSPLGAFKPKRIGHITLAKKFVKLFPYTMSESVRKSVSSCLDEAAKRGLELDFNTAGLRKPYAGNVYMEEWMIKEAEQ
KNIPLVFGSDAHQAEDAGFGYEHFESRFVK
>Mature_270_residues
MLKRDGHVHSPFCPHGSKDEFRYYIEELCKKGFQSVSFTEHAPLPPSFIDPTPEKDSAMPISQLGRYIERLTELKEEYRG
QLDILIGLEVDYIRAFEHETKAFLDQYGTHLDDSILSVHFLPAGSSYICLDYDEKAFQQLIDCYGSTEQVYLAYYDEIYS
SIVSPLGAFKPKRIGHITLAKKFVKLFPYTMSESVRKSVSSCLDEAAKRGLELDFNTAGLRKPYAGNVYMEEWMIKEAEQ
KNIPLVFGSDAHQAEDAGFGYEHFESRFVK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 30936; Mature: 30936

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRDGHVHSPFCPHGSKDEFRYYIEELCKKGFQSVSFTEHAPLPPSFIDPTPEKDSAMP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ISQLGRYIERLTELKEEYRGQLDILIGLEVDYIRAFEHETKAFLDQYGTHLDDSILSVHF
HHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LPAGSSYICLDYDEKAFQQLIDCYGSTEQVYLAYYDEIYSSIVSPLGAFKPKRIGHITLA
ECCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KKFVKLFPYTMSESVRKSVSSCLDEAAKRGLELDFNTAGLRKPYAGNVYMEEWMIKEAEQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHH
KNIPLVFGSDAHQAEDAGFGYEHFESRFVK
CCCCEEECCCCCHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLKRDGHVHSPFCPHGSKDEFRYYIEELCKKGFQSVSFTEHAPLPPSFIDPTPEKDSAMP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ISQLGRYIERLTELKEEYRGQLDILIGLEVDYIRAFEHETKAFLDQYGTHLDDSILSVHF
HHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LPAGSSYICLDYDEKAFQQLIDCYGSTEQVYLAYYDEIYSSIVSPLGAFKPKRIGHITLA
ECCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KKFVKLFPYTMSESVRKSVSSCLDEAAKRGLELDFNTAGLRKPYAGNVYMEEWMIKEAEQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHH
KNIPLVFGSDAHQAEDAGFGYEHFESRFVK
CCCCEEECCCCCHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10322033 [H]