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The map label for this gene is sppA [H]

Identifier: 52786819

GI number: 52786819

Start: 2977436

End: 2978443

Strand: Reverse

Name: sppA [H]

Synonym: BLi03092

Alternate gene names: 52786819

Gene position: 2978443-2977436 (Counterclockwise)

Preceding gene: 52786821

Following gene: 52786818

Centisome position: 70.54

GC content: 46.73

Gene sequence:

>1008_bases
ATGAATGCGAAAAGATGGATCGCACTTGTCATCGCGCTGGGCGTTTTTGCGTTATCTGCGGTGATGAGCCTTTTGCTTGC
AGTATTTGACACGATGGGGAATGACGGAAAGATGCAGTTTGGCCTCAATGACACCCAGGAAGAAACGGTGCTTGAACAAG
GAAACAGCTCAAGAAAAATCGCCGTTCTTGAAGTGAACGGAACGATTTCCGACAATGGCGGCGCTTCAGGCCTGTTCAGC
TCTGAAGGCTACAACCACAGATCGTTTTTGCAAATGCTTGAAAAAGCAAAAGACGATTCTGCCGTAAAGGGCATTGTTCT
GCGCGTCAATTCTCCGGGTGGCGGAGTATACGAGAGCGCTGAGATACATAAGAAGCTTGAAGAGATCAAAAAAGATACGA
AAAAACCGATTTACGTATCAATGGGATCGATGGCTGCGTCCGGCGGCTATTACATTTCAACGCCTGCCGACAAAATCTTT
GCAGCGCCTGACACGCTGACGGGTTCACTCGGGGTCATCATGGAAAGCCTTAACTACAGCAAGCTTGCAGAGAAGCTTGG
ATTAAAAACGGAGACGATTAAAAGCGGTGAGTTTAAAGATATCATGTCACCGACGCGCGATATGACGAAAAAAGAAAGAG
AAATCATGCAGTCAATGGTCGATGACGCGTACGAAGGGTTTGTAGATGTTATTGCCGAAGGGCGCGGCATGTCCGAAAAT
GACGTGAAAAAAATTGCCGACGGACGTGTCTATGACGGCCGCCAGGCGAAACAGAACCATCTCATTGATGAGCTCGGCTA
TTATGAAGATGCGGTCAAAGCGATGAAAAAGGACCACAAAAACCTTGCCGGCGCATCTGTTGTCAGCTATGAAGAATCAG
CCGGCCTTGCCTCGCTGTTTTCAATGACTGCAAATAAGATGTTTAAAAGCGAAGCTGATTTCTTAAACATTAAAGAAGCG
ATTTCTCAATCCGGTGCACCGAGACTCATGTATTTATATGCCAAATAG

Upstream 100 bases:

>100_bases
AAAACTTCTTGTATATGAAGCGGCATCATAATGAACTTTTTCTCTTCATATACGTACTAAGACATGCAGCTTTTTTATTC
AAAGGAGGAGAACAGACAAA

Downstream 100 bases:

>100_bases
GAGGGGACCGAAAAAATGGATGTGACTTATGATGGAAAGGATCATAATGAATTATCGCCGAATGTCGGCGTTTCCAGGGA
AGAATCGGCCCCGCATGTAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNAKRWIALVIALGVFALSAVMSLLLAVFDTMGNDGKMQFGLNDTQEETVLEQGNSSRKIAVLEVNGTISDNGGASGLFS
SEGYNHRSFLQMLEKAKDDSAVKGIVLRVNSPGGGVYESAEIHKKLEEIKKDTKKPIYVSMGSMAASGGYYISTPADKIF
AAPDTLTGSLGVIMESLNYSKLAEKLGLKTETIKSGEFKDIMSPTRDMTKKEREIMQSMVDDAYEGFVDVIAEGRGMSEN
DVKKIADGRVYDGRQAKQNHLIDELGYYEDAVKAMKKDHKNLAGASVVSYEESAGLASLFSMTANKMFKSEADFLNIKEA
ISQSGAPRLMYLYAK

Sequences:

>Translated_335_residues
MNAKRWIALVIALGVFALSAVMSLLLAVFDTMGNDGKMQFGLNDTQEETVLEQGNSSRKIAVLEVNGTISDNGGASGLFS
SEGYNHRSFLQMLEKAKDDSAVKGIVLRVNSPGGGVYESAEIHKKLEEIKKDTKKPIYVSMGSMAASGGYYISTPADKIF
AAPDTLTGSLGVIMESLNYSKLAEKLGLKTETIKSGEFKDIMSPTRDMTKKEREIMQSMVDDAYEGFVDVIAEGRGMSEN
DVKKIADGRVYDGRQAKQNHLIDELGYYEDAVKAMKKDHKNLAGASVVSYEESAGLASLFSMTANKMFKSEADFLNIKEA
ISQSGAPRLMYLYAK
>Mature_335_residues
MNAKRWIALVIALGVFALSAVMSLLLAVFDTMGNDGKMQFGLNDTQEETVLEQGNSSRKIAVLEVNGTISDNGGASGLFS
SEGYNHRSFLQMLEKAKDDSAVKGIVLRVNSPGGGVYESAEIHKKLEEIKKDTKKPIYVSMGSMAASGGYYISTPADKIF
AAPDTLTGSLGVIMESLNYSKLAEKLGLKTETIKSGEFKDIMSPTRDMTKKEREIMQSMVDDAYEGFVDVIAEGRGMSEN
DVKKIADGRVYDGRQAKQNHLIDELGYYEDAVKAMKKDHKNLAGASVVSYEESAGLASLFSMTANKMFKSEADFLNIKEA
ISQSGAPRLMYLYAK

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=180, Percent_Identity=40, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787527, Length=171, Percent_Identity=27.4853801169591, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 36509; Mature: 36509

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKRWIALVIALGVFALSAVMSLLLAVFDTMGNDGKMQFGLNDTQEETVLEQGNSSRKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCEE
AVLEVNGTISDNGGASGLFSSEGYNHRSFLQMLEKAKDDSAVKGIVLRVNSPGGGVYESA
EEEEECCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHH
EIHKKLEEIKKDTKKPIYVSMGSMAASGGYYISTPADKIFAAPDTLTGSLGVIMESLNYS
HHHHHHHHHHHHCCCCEEEEECCEECCCCEEEECCCHHHEECCCCCCCHHHHHHHHCCHH
KLAEKLGLKTETIKSGEFKDIMSPTRDMTKKEREIMQSMVDDAYEGFVDVIAEGRGMSEN
HHHHHHCCCHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DVKKIADGRVYDGRQAKQNHLIDELGYYEDAVKAMKKDHKNLAGASVVSYEESAGLASLF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHCHHHHHH
SMTANKMFKSEADFLNIKEAISQSGAPRLMYLYAK
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MNAKRWIALVIALGVFALSAVMSLLLAVFDTMGNDGKMQFGLNDTQEETVLEQGNSSRKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCEE
AVLEVNGTISDNGGASGLFSSEGYNHRSFLQMLEKAKDDSAVKGIVLRVNSPGGGVYESA
EEEEECCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHH
EIHKKLEEIKKDTKKPIYVSMGSMAASGGYYISTPADKIFAAPDTLTGSLGVIMESLNYS
HHHHHHHHHHHHCCCCEEEEECCEECCCCEEEECCCHHHEECCCCCCCHHHHHHHHCCHH
KLAEKLGLKTETIKSGEFKDIMSPTRDMTKKEREIMQSMVDDAYEGFVDVIAEGRGMSEN
HHHHHHCCCHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DVKKIADGRVYDGRQAKQNHLIDELGYYEDAVKAMKKDHKNLAGASVVSYEESAGLASLF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHCHHHHHH
SMTANKMFKSEADFLNIKEAISQSGAPRLMYLYAK
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]