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The map label for this gene is nreC [H]

Identifier: 52786522

GI number: 52786522

Start: 2677226

End: 2677870

Strand: Reverse

Name: nreC [H]

Synonym: BLi02787

Alternate gene names: 52786522

Gene position: 2677870-2677226 (Counterclockwise)

Preceding gene: 52786523

Following gene: 52786521

Centisome position: 63.42

GC content: 43.72

Gene sequence:

>645_bases
GTGATCAGGGTATTGCTGGTCGATGACCATATGATGATTCGCAAGGGCATCCGTGTCCTTTTGGAAGGCTTTTCTGGAAT
TGAAATTGCGGGAGAAAGCAATAATGGCAACGAAGCCGTTCTTAGCGCCGGACAGTTAAAGCCGGATGTCGTGCTGATGG
ATTTGTCGATGCCGAACGGGTTGGACGGATTCACAGCGAGCAGTGAGATCCGAAAGTTGAATCCTTCTGTTAAAATCGTG
ATTTTGACAATGCATGATGAGGAAATTTTTGTCCAAAAAGCAATAGAGGCGGGGGCGCATGGCTACGTCTTGAAAAACAG
CCATTATCGGTTGCTTTATCAGGCGATTGTCGAAGTGTACAGGAGCAATCTCTTTTACAAAACATCTGTATCGCAAGACA
TCATTGATCAATGGCTCAATTCAGAGCCCAAAAAGCCGACCTCTGTATTAACTGTCCGCGAAAAGGAGATTCTCAGATTC
ATTGTGCTGGGTTATGCCAATAAGGAGATTGCCGATAAACTCTCAATCAGCGTCAAAACCGTCGAAAACCACAAAACGAA
TATGATGCAGAAGTTAGATCTGGACTCGAAACACGAATTGATTCAATATGCGATCAAAAATAAATATCTCGATCTGTCGT
TGTAA

Upstream 100 bases:

>100_bases
GAGAGAGTCGATCAGATGGATGGAAGTCTTCGAATTCACTCTGCACTTCAGAGTGGCACGACGATTAAAGTGAAAGTACA
GGACAAGGAGGGGAAGGAGA

Downstream 100 bases:

>100_bases
CATACGGCCCCTTAACCCCTGTCAGCTTGTGAAGACGGAGCTCACATAAAAGTAGGGGAGTTCCCCTATACAGAAAAAGG
AAGATTGATGTTAACTTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIRVLLVDDHMMIRKGIRVLLEGFSGIEIAGESNNGNEAVLSAGQLKPDVVLMDLSMPNGLDGFTASSEIRKLNPSVKIV
ILTMHDEEIFVQKAIEAGAHGYVLKNSHYRLLYQAIVEVYRSNLFYKTSVSQDIIDQWLNSEPKKPTSVLTVREKEILRF
IVLGYANKEIADKLSISVKTVENHKTNMMQKLDLDSKHELIQYAIKNKYLDLSL

Sequences:

>Translated_214_residues
MIRVLLVDDHMMIRKGIRVLLEGFSGIEIAGESNNGNEAVLSAGQLKPDVVLMDLSMPNGLDGFTASSEIRKLNPSVKIV
ILTMHDEEIFVQKAIEAGAHGYVLKNSHYRLLYQAIVEVYRSNLFYKTSVSQDIIDQWLNSEPKKPTSVLTVREKEILRF
IVLGYANKEIADKLSISVKTVENHKTNMMQKLDLDSKHELIQYAIKNKYLDLSL
>Mature_214_residues
MIRVLLVDDHMMIRKGIRVLLEGFSGIEIAGESNNGNEAVLSAGQLKPDVVLMDLSMPNGLDGFTASSEIRKLNPSVKIV
ILTMHDEEIFVQKAIEAGAHGYVLKNSHYRLLYQAIVEVYRSNLFYKTSVSQDIIDQWLNSEPKKPTSVLTVREKEILRF
IVLGYANKEIADKLSISVKTVENHKTNMMQKLDLDSKHELIQYAIKNKYLDLSL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=36.5384615384615, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=35.8974358974359, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=35.3233830845771, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=30.9178743961353, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=30.5, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=28.921568627451, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=31.5217391304348, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082052, Length=107, Percent_Identity=38.3177570093458, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24219; Mature: 24219

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLLVDDHMMIRKGIRVLLEGFSGIEIAGESNNGNEAVLSAGQLKPDVVLMDLSMPNG
CEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCCCEEEEEECCCCC
LDGFTASSEIRKLNPSVKIVILTMHDEEIFVQKAIEAGAHGYVLKNSHYRLLYQAIVEVY
CCCCCCCCHHHHCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
RSNLFYKTSVSQDIIDQWLNSEPKKPTSVLTVREKEILRFIVLGYANKEIADKLSISVKT
HHCCEEEECCCHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHEEEEEE
VENHKTNMMQKLDLDSKHELIQYAIKNKYLDLSL
ECCHHHHHHHHCCCCCHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MIRVLLVDDHMMIRKGIRVLLEGFSGIEIAGESNNGNEAVLSAGQLKPDVVLMDLSMPNG
CEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCCCEEEEEECCCCC
LDGFTASSEIRKLNPSVKIVILTMHDEEIFVQKAIEAGAHGYVLKNSHYRLLYQAIVEVY
CCCCCCCCHHHHCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
RSNLFYKTSVSQDIIDQWLNSEPKKPTSVLTVREKEILRFIVLGYANKEIADKLSISVKT
HHCCEEEECCCHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHEEEEEE
VENHKTNMMQKLDLDSKHELIQYAIKNKYLDLSL
ECCHHHHHHHHCCCCCHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]