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The map label for this gene is ypnP [H]

Identifier: 52786051

GI number: 52786051

Start: 2259978

End: 2261309

Strand: Reverse

Name: ypnP [H]

Synonym: BLi02307

Alternate gene names: 52786051

Gene position: 2261309-2259978 (Counterclockwise)

Preceding gene: 52786053

Following gene: 52786050

Centisome position: 53.55

GC content: 48.2

Gene sequence:

>1332_bases
ATGAAAACGGACTTTACATACGGAAATGTATTTAAACAGCTGGTCTATTTTTCCGGACCGATCATTTTAGCCAATCTTTT
GCAGATTTCATTCCAATTCGTCGACAGCTTGTGGGTCGGAAATCTGCTCGGAGCAAAAGCTCTTGGTGCTGCGGCCGTCT
CAGGAACGGTTTTCTTTACGGTGCTGTCGTTCGTATTGGGCGTCAACAATGCGGCGCTGACGATTCTTGCGCAGCAAAAA
GGAAAAGGGGATAAAAAGGGACTGGCATCATATGTAAACGCGTTTGTCGTTCTGATGACGGCGATGAGCGTATTGCTCGG
GGTTATCGGCTATTTTTTCACAGAGCCTTTGCTCTCGCTACTTCAAACGCCTGGCAATATGATGGATTTGGCCGTAAGCT
ATTTGAGGATTCATTTTATCGGGATTATATTTTTATTCGGCTATAATTTCATCAGTACAGTATTAAGAGCGGTCGGCGAC
AGTCAAACACCTTTGCGTTTCGTCCTGTTGGCCGTCATCCTGAACCTGTTCATGGATCCGCTGTTTATCTCGGTATTCAA
CCTCGGAATTGCCGGAGCGGCCTATGCAACCGTCGTGTCCCAAGGGATTGCTTTTATTTACGGAGTGGTCTATACGGTGA
GAAAGCAGCTTGTTCCATTTTCAAAGCCGGCGCTTCCATCGCTGGCAGAGACGTCCGTCATTTTGAAGCTCGGAGTGCCT
GCCGGCTTGCAAATGATGGTGATTTCAGGCGGCTCGATGGCGATTATGAGCGTTGTCAATTCATTTGGAGAAAGCGTCGT
GTCAGGGTTTGGCGCGGTACAGCGGCTTGACAGCCTGCTGATTCTCCCAGCGATGGCCATCGGCACGGCTGTCAACAGTA
TGGCTGGCCAAACCTTCGGAAGCGGCGACATGGAGCGTACGAAAAAAATCGCCAACTACGGCGTCATTTATGTCCTGCTG
TTTATGGCTGCCGTCAGCACCGCGATATTTCTGACAGGCTATCACGCGGTCAGGCTGTTTATATCGGAAGCCGATTCAGC
CGCATTCGGGGAAGAGTATTTAAAAACGATTGCTTTTTTCTATCCGTTTATCGGAATTAACTTTGTGTTGAACGGTGTTG
TAAGGGCAGCCGGAGCGATGTTTCAAATTTTGGTGCTGAACGTGATTTCTTTTTGGGCTTTGCGCTATCCGTTTACATAT
CTATTTTCAAAGTGGCTTGGCGAGAACGGCATAGCGCTGGGCATCGGAATGAGCTTTATGCTGAGCAGCCTGACCGCCTT
TTTATATTACCGCTACGGGAAGTGGAAGCACCTCGTTCTATTTGAAAAATGA

Upstream 100 bases:

>100_bases
AACATCTTGTCACGCCCCTTTGCATGCTTTCTGACATCATATGAGGCTGCGAAGCCATCGGTCACATGTGATCAAGACGA
CAGATGAAAAGGAGAAAACA

Downstream 100 bases:

>100_bases
AAGCAAGCTCCTCCGGCAAGCCTCGGAAACCAGATCCCGCCGGGCGTCTGAAGAAAGGAACAAAAATGCTTTTAACGTCT
TAATAATTGACGATATATAC

Product: YpnP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKTDFTYGNVFKQLVYFSGPIILANLLQISFQFVDSLWVGNLLGAKALGAAAVSGTVFFTVLSFVLGVNNAALTILAQQK
GKGDKKGLASYVNAFVVLMTAMSVLLGVIGYFFTEPLLSLLQTPGNMMDLAVSYLRIHFIGIIFLFGYNFISTVLRAVGD
SQTPLRFVLLAVILNLFMDPLFISVFNLGIAGAAYATVVSQGIAFIYGVVYTVRKQLVPFSKPALPSLAETSVILKLGVP
AGLQMMVISGGSMAIMSVVNSFGESVVSGFGAVQRLDSLLILPAMAIGTAVNSMAGQTFGSGDMERTKKIANYGVIYVLL
FMAAVSTAIFLTGYHAVRLFISEADSAAFGEEYLKTIAFFYPFIGINFVLNGVVRAAGAMFQILVLNVISFWALRYPFTY
LFSKWLGENGIALGIGMSFMLSSLTAFLYYRYGKWKHLVLFEK

Sequences:

>Translated_443_residues
MKTDFTYGNVFKQLVYFSGPIILANLLQISFQFVDSLWVGNLLGAKALGAAAVSGTVFFTVLSFVLGVNNAALTILAQQK
GKGDKKGLASYVNAFVVLMTAMSVLLGVIGYFFTEPLLSLLQTPGNMMDLAVSYLRIHFIGIIFLFGYNFISTVLRAVGD
SQTPLRFVLLAVILNLFMDPLFISVFNLGIAGAAYATVVSQGIAFIYGVVYTVRKQLVPFSKPALPSLAETSVILKLGVP
AGLQMMVISGGSMAIMSVVNSFGESVVSGFGAVQRLDSLLILPAMAIGTAVNSMAGQTFGSGDMERTKKIANYGVIYVLL
FMAAVSTAIFLTGYHAVRLFISEADSAAFGEEYLKTIAFFYPFIGINFVLNGVVRAAGAMFQILVLNVISFWALRYPFTY
LFSKWLGENGIALGIGMSFMLSSLTAFLYYRYGKWKHLVLFEK
>Mature_443_residues
MKTDFTYGNVFKQLVYFSGPIILANLLQISFQFVDSLWVGNLLGAKALGAAAVSGTVFFTVLSFVLGVNNAALTILAQQK
GKGDKKGLASYVNAFVVLMTAMSVLLGVIGYFFTEPLLSLLQTPGNMMDLAVSYLRIHFIGIIFLFGYNFISTVLRAVGD
SQTPLRFVLLAVILNLFMDPLFISVFNLGIAGAAYATVVSQGIAFIYGVVYTVRKQLVPFSKPALPSLAETSVILKLGVP
AGLQMMVISGGSMAIMSVVNSFGESVVSGFGAVQRLDSLLILPAMAIGTAVNSMAGQTFGSGDMERTKKIANYGVIYVLL
FMAAVSTAIFLTGYHAVRLFISEADSAAFGEEYLKTIAFFYPFIGINFVLNGVVRAAGAMFQILVLNVISFWALRYPFTY
LFSKWLGENGIALGIGMSFMLSSLTAFLYYRYGKWKHLVLFEK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI153792564, Length=410, Percent_Identity=22.9268292682927, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48008; Mature: 48008

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCEEEEEEECC
>Mature Secondary Structure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HHHHHHHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]