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The map label for this gene is kamA [H]

Identifier: 52786038

GI number: 52786038

Start: 2247627

End: 2249036

Strand: Reverse

Name: kamA [H]

Synonym: BLi02294

Alternate gene names: 52786038

Gene position: 2249036-2247627 (Counterclockwise)

Preceding gene: 52786039

Following gene: 52786037

Centisome position: 53.26

GC content: 49.57

Gene sequence:

>1410_bases
ATGGAAAACGGTCTGTTTAAGCCGAAAAGGCACTGGAAGGATATTGAGCTTTGGAAAGATGTTCCCGAGGAAAAATGGAA
CGACTGGATATGGCAGCTGACCAACACCGTCAGAACGCTTGAAGATTTGAAAAAAGTCGTCAATCTTACGAAAGAGGAAG
AAGAAGGGGTGCGAATCTCCACAAAGACGATCCCTTTAAATATCACGCCGTATTACGCCTCACTGATGAATCCGGATGAT
CCGCGCTGTCCGATCAGAATGCAGTCGGTGCCGCTCGCAGAAGAAATGCACAAAACAAAATACGACCTTGAAGATCCCCT
TCATGAGGATGAAGATTCGCCTGTCCCCGGCTTAACCCACCGCTATCCGGACCGGGTTTTGTTTCTCGTCACTAATCAAT
GCTCGATGTATTGCAGATACTGTACAAGGCGGCGTTTTTCCGGGCAAATCGGCATGGGCGTGCCGAAAAAGCAGCTCGAT
CAGGCGATCGGCTATATTCGGGATACGCCTGATGTCAGGGATGTGCTGATATCAGGCGGGGACGGCCTCCTCATTAACGA
CCAGATCCTTGAATATATTTTGAAAAACCTCCGCGCCATTCCGCACGTGGAAATCATTCGGATCGGCACAAGGGCCCCAG
TCGTCTTCCCGCAGCGGATTACCGACAAGCTATGCAGCATTTTGAAAAAGTATCATCCCGTCTGGCTGAATACGCATTTC
AACACGAGCATTGAAATCACGAAGGAAGCGAAGGAAGCCTGTGAGAAGCTGGTCAATGCCGGGGTGCCGGTCGGCAATCA
AGCCGTTATTTTGGCAGGCATTAATGACAGCGTTTCCATTATGAAAAAGCTGATGCATGATTTGGTGAAAATCAGAGTCC
GTCCGTATTATATTTATCAATGCGACTTGTCTGAAGGAATCGGCCATTTCCGAGCGCCTGTATCAAAGGGGCTTGAAATC
ATTGAAGGCTTGCGCGGCCACACGAGCGGCTATGCAGTGCCGACCTTTGTCGTTGACGCGCCGGGCGGAGGCGGGAAAAT
CGCCATCCAGCCGAATTACTTGATTTCGCAAAGCCCCGATAAAGTCGTGCTCCGCAATTTTGAAGGCGTCATTACGTCGT
ATCCTGAGCCTGAAAACTATGTTCCGGGGAGAGCGGACGACTATTTTGCCGAAATCTTCCCTGATGTGATGAAGGAAAAA
GAGGAGATCGGCATATCGGCAATCTATGCGGATCAAGCTCTTTCATACACACCGGACGGCTTAAAACGGCTCGAGAGAAG
AGAAAGCTATTCCAAGAGGCCTGATCATGAAACATTGAAAAGCCGCCGGGCAAAGCGCGATGAATTGAAAGAAAAGAAAT
TCCTTGCCCAGCAAAAGAAAGAAGGCGAAGCTGAGGGGCATGCGCAATGA

Upstream 100 bases:

>100_bases
AAAAAGTGGTCTTCCGCGGGTTTTACATTTGAAGAGACACTTTTCATGCCGGTCACATAACCTGAAAAGTATAGGGAAAA
TGCTGATAGGGGGATGGAAG

Downstream 100 bases:

>100_bases
AGAAGTGTGAATGGTGCAATGAAGAAAAAGCCGCGGCAGCCCGCACGGCGGTATATTGGGAGCTTCCCGACGGGACGAAA
GCGATTGAAATCACCGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MENGLFKPKRHWKDIELWKDVPEEKWNDWIWQLTNTVRTLEDLKKVVNLTKEEEEGVRISTKTIPLNITPYYASLMNPDD
PRCPIRMQSVPLAEEMHKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
QAIGYIRDTPDVRDVLISGGDGLLINDQILEYILKNLRAIPHVEIIRIGTRAPVVFPQRITDKLCSILKKYHPVWLNTHF
NTSIEITKEAKEACEKLVNAGVPVGNQAVILAGINDSVSIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIAIQPNYLISQSPDKVVLRNFEGVITSYPEPENYVPGRADDYFAEIFPDVMKEK
EEIGISAIYADQALSYTPDGLKRLERRESYSKRPDHETLKSRRAKRDELKEKKFLAQQKKEGEAEGHAQ

Sequences:

>Translated_469_residues
MENGLFKPKRHWKDIELWKDVPEEKWNDWIWQLTNTVRTLEDLKKVVNLTKEEEEGVRISTKTIPLNITPYYASLMNPDD
PRCPIRMQSVPLAEEMHKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
QAIGYIRDTPDVRDVLISGGDGLLINDQILEYILKNLRAIPHVEIIRIGTRAPVVFPQRITDKLCSILKKYHPVWLNTHF
NTSIEITKEAKEACEKLVNAGVPVGNQAVILAGINDSVSIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIAIQPNYLISQSPDKVVLRNFEGVITSYPEPENYVPGRADDYFAEIFPDVMKEK
EEIGISAIYADQALSYTPDGLKRLERRESYSKRPDHETLKSRRAKRDELKEKKFLAQQKKEGEAEGHAQ
>Mature_469_residues
MENGLFKPKRHWKDIELWKDVPEEKWNDWIWQLTNTVRTLEDLKKVVNLTKEEEEGVRISTKTIPLNITPYYASLMNPDD
PRCPIRMQSVPLAEEMHKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
QAIGYIRDTPDVRDVLISGGDGLLINDQILEYILKNLRAIPHVEIIRIGTRAPVVFPQRITDKLCSILKKYHPVWLNTHF
NTSIEITKEAKEACEKLVNAGVPVGNQAVILAGINDSVSIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIAIQPNYLISQSPDKVVLRNFEGVITSYPEPENYVPGRADDYFAEIFPDVMKEK
EEIGISAIYADQALSYTPDGLKRLERRESYSKRPDHETLKSRRAKRDELKEKKFLAQQKKEGEAEGHAQ

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=321, Percent_Identity=31.7757009345794, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR006638
- InterPro:   IPR022459 [H]

Pfam domain/function: NA

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 53613; Mature: 53613

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGLFKPKRHWKDIELWKDVPEEKWNDWIWQLTNTVRTLEDLKKVVNLTKEEEEGVRIS
CCCCCCCCHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
TKTIPLNITPYYASLMNPDDPRCPIRMQSVPLAEEMHKTKYDLEDPLHEDEDSPVPGLTH
EEEEEEEECHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDQAIGYIRDTPDVRDVLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEEECC
DGLLINDQILEYILKNLRAIPHVEIIRIGTRAPVVFPQRITDKLCSILKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIEITKEAKEACEKLVNAGVPVGNQAVILAGINDSVSIMKKLMHDLVKIRVRPYYIYQ
CCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVPTFVVDAPGGGGKIAIQPNYLISQSPD
ECHHHCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEECCCEEECCCCC
KVVLRNFEGVITSYPEPENYVPGRADDYFAEIFPDVMKEKEEIGISAIYADQALSYTPDG
HHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
LKRLERRESYSKRPDHETLKSRRAKRDELKEKKFLAQQKKEGEAEGHAQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MENGLFKPKRHWKDIELWKDVPEEKWNDWIWQLTNTVRTLEDLKKVVNLTKEEEEGVRIS
CCCCCCCCHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
TKTIPLNITPYYASLMNPDDPRCPIRMQSVPLAEEMHKTKYDLEDPLHEDEDSPVPGLTH
EEEEEEEECHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDQAIGYIRDTPDVRDVLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEEECC
DGLLINDQILEYILKNLRAIPHVEIIRIGTRAPVVFPQRITDKLCSILKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIEITKEAKEACEKLVNAGVPVGNQAVILAGINDSVSIMKKLMHDLVKIRVRPYYIYQ
CCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVPTFVVDAPGGGGKIAIQPNYLISQSPD
ECHHHCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEECCCEEECCCCC
KVVLRNFEGVITSYPEPENYVPGRADDYFAEIFPDVMKEKEEIGISAIYADQALSYTPDG
HHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
LKRLERRESYSKRPDHETLKSRRAKRDELKEKKFLAQQKKEGEAEGHAQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377; 10839984 [H]