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The map label for this gene is yocI [H]

Identifier: 52785962

GI number: 52785962

Start: 2173539

End: 2175320

Strand: Reverse

Name: yocI [H]

Synonym: BLi02214

Alternate gene names: 52785962

Gene position: 2175320-2173539 (Counterclockwise)

Preceding gene: 52785963

Following gene: 52785961

Centisome position: 51.52

GC content: 47.36

Gene sequence:

>1782_bases
ATGCTAGAGAAAGCCGAAGCACTATTGCAGCACTATTTTGGCTATCCTTCACTGCGCCCGGGGCAGAAGAAAGCCATTCA
ATCTGTCGTTTCTGAAAAGCGAGATACAGCATGCATTATGCCGACGGGCGGAGGCAAATCAATCTGCTACCAAATTCCCG
CGCTCCTTATGGAAGGGACAACCATTGTGATCTCTCCTTTAATTTCCTTGATGAAGGACCAGGTGGATGCTTTAAATCAG
CTTGGAATTCAAGCTGCGTACGTGAACAGTTCTTTAGGCCATAACGAAATCGCTGAGCGGCTCTCCGTATTTAAGGAAGG
CGGCTACAAGCTCTTTTATGTAACACCTGAGCGGCTGACGTCTCCCGAATTCATTCGCGCGATTTCCCACATTCATATTC
CGCTGGTAGCCATTGATGAAGCTCATTGCATTTCACAGTGGGGACATGATTTCAGGCCGAGCTACAGACATATTGAAGGC
TTTTTAAATAGCCTCGGCACCCGCCCGGTTGTATTGGCGTTGACGGCTACCGCAACGCCCGAGGTTCATGAGGATATTTG
CACACAGCTCGGGATCGAAAAAGAGAACACGGTTTTTACCGGTTTTTCACGGGATAATTTGACGTTTAAAATTTTAAAAG
GCGAAAACAGGGACCGTTTTATCGAATCATATGTGGAGAAAAACCGCTCAGAGGCGGGAATTATCTATACAGCGACAAGA
AAGGAAGCCGAAAGAATATCAAGCCGCCTCTCTCAAAAAGGAATTGCGGCCGGGTGCTATCACGGCGGGATGGATGATGA
AGAAAGAGACCGGCAGCAGGATCTCTTTTTAAATGATGAGATCAGTGTAATGACAGCGACCTCGGCGTTTGGAATGGGCA
TCGATAAATCCAATATCCGCTATGTGATTCATGCCCAAATTCCAAAAAATATGGAGAGCTACTACCAGGAGGCGGGACGA
GCCGGACGCGACGGCCTTGACAGCGAGTGCATCCTGCTGTTTTCCCCTCAGGACATTCGGCTTCAGCGGTTTTTAATCGA
ACAGTCGACAGAAGATGAAGACATTCGGGCGCAAGACGTGAAAAAACTGAGGCAAATGGTTGATTTTTGCCATACGGAAG
GCTGTCTCGAACGGTTTATTCTTTCTTATTTTGGCGAAGTTCCAACCGAAGACTGCGGCAGGTGCGGCAGCTGTCTCGAC
ACCCGAAGCATCACCGATGTGACGAAGGAGGCACAGATGGTGCTGTCCTGCATCATCCGCATGGGAGAAAGGTTCGGAAA
AACCATGGTGGCGCAAGTTCTGGCAGGTTCGAAAAATAAGAAAGTGACCGAAAACGGCTTCCAGCAATTATCGACTTACG
GAATTTTAAAGAAACGGTCTATTGCCGACATAAGCGATTTTATAGAGTTTTTAATCGCAGATGAGTACATCAAAATGTCC
GACGGGACATATCCTGTTCTCTTTGTCGCCAACAAGGGGCGAAACGTTTTGCTCGGCCGGGAAGCGGTGATGCGCAAAGA
AAAAATGCAAACAAATCAAATCGTTAAAGATGACGAATTGTTTGAACGGTTAAGGGCGCTGCGCAGAAAGCTTGCTCAGG
AACAAGGCGTGCCTCCTTTTGTTGTATTCTCTGACGAAACGCTGCGGGAAATGAGCGGGAAAGTCCCTCTGACAGACGAA
GAGCTTTTGTCAGTCAAAGGAGTGGGAGAACAAAAAAGAGTAAAATACGGAGCTGTATTTCTACAGGAGCTTCAAGCCTA
TAAAACTGAGAAAGAAGCATAA

Upstream 100 bases:

>100_bases
ATCGATTAGACGATTTTACGGGGAGAGGCTGATTGCCGGTTTAAATATGATATCATGGGGGACAGGAAGAAGTTTAATGA
TAAGAGAGGGTTTCATTTAT

Downstream 100 bases:

>100_bases
AAACCCAAAATTTATATATGTAAAATTTTTTTTAGTAAATCTCCTATTTCAGTTGAAAAACGATTGGAACCCTTGATACA
TCTGAATTTCGGCCGATTTT

Product: YocI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MLEKAEALLQHYFGYPSLRPGQKKAIQSVVSEKRDTACIMPTGGGKSICYQIPALLMEGTTIVISPLISLMKDQVDALNQ
LGIQAAYVNSSLGHNEIAERLSVFKEGGYKLFYVTPERLTSPEFIRAISHIHIPLVAIDEAHCISQWGHDFRPSYRHIEG
FLNSLGTRPVVLALTATATPEVHEDICTQLGIEKENTVFTGFSRDNLTFKILKGENRDRFIESYVEKNRSEAGIIYTATR
KEAERISSRLSQKGIAAGCYHGGMDDEERDRQQDLFLNDEISVMTATSAFGMGIDKSNIRYVIHAQIPKNMESYYQEAGR
AGRDGLDSECILLFSPQDIRLQRFLIEQSTEDEDIRAQDVKKLRQMVDFCHTEGCLERFILSYFGEVPTEDCGRCGSCLD
TRSITDVTKEAQMVLSCIIRMGERFGKTMVAQVLAGSKNKKVTENGFQQLSTYGILKKRSIADISDFIEFLIADEYIKMS
DGTYPVLFVANKGRNVLLGREAVMRKEKMQTNQIVKDDELFERLRALRRKLAQEQGVPPFVVFSDETLREMSGKVPLTDE
ELLSVKGVGEQKRVKYGAVFLQELQAYKTEKEA

Sequences:

>Translated_593_residues
MLEKAEALLQHYFGYPSLRPGQKKAIQSVVSEKRDTACIMPTGGGKSICYQIPALLMEGTTIVISPLISLMKDQVDALNQ
LGIQAAYVNSSLGHNEIAERLSVFKEGGYKLFYVTPERLTSPEFIRAISHIHIPLVAIDEAHCISQWGHDFRPSYRHIEG
FLNSLGTRPVVLALTATATPEVHEDICTQLGIEKENTVFTGFSRDNLTFKILKGENRDRFIESYVEKNRSEAGIIYTATR
KEAERISSRLSQKGIAAGCYHGGMDDEERDRQQDLFLNDEISVMTATSAFGMGIDKSNIRYVIHAQIPKNMESYYQEAGR
AGRDGLDSECILLFSPQDIRLQRFLIEQSTEDEDIRAQDVKKLRQMVDFCHTEGCLERFILSYFGEVPTEDCGRCGSCLD
TRSITDVTKEAQMVLSCIIRMGERFGKTMVAQVLAGSKNKKVTENGFQQLSTYGILKKRSIADISDFIEFLIADEYIKMS
DGTYPVLFVANKGRNVLLGREAVMRKEKMQTNQIVKDDELFERLRALRRKLAQEQGVPPFVVFSDETLREMSGKVPLTDE
ELLSVKGVGEQKRVKYGAVFLQELQAYKTEKEA
>Mature_593_residues
MLEKAEALLQHYFGYPSLRPGQKKAIQSVVSEKRDTACIMPTGGGKSICYQIPALLMEGTTIVISPLISLMKDQVDALNQ
LGIQAAYVNSSLGHNEIAERLSVFKEGGYKLFYVTPERLTSPEFIRAISHIHIPLVAIDEAHCISQWGHDFRPSYRHIEG
FLNSLGTRPVVLALTATATPEVHEDICTQLGIEKENTVFTGFSRDNLTFKILKGENRDRFIESYVEKNRSEAGIIYTATR
KEAERISSRLSQKGIAAGCYHGGMDDEERDRQQDLFLNDEISVMTATSAFGMGIDKSNIRYVIHAQIPKNMESYYQEAGR
AGRDGLDSECILLFSPQDIRLQRFLIEQSTEDEDIRAQDVKKLRQMVDFCHTEGCLERFILSYFGEVPTEDCGRCGSCLD
TRSITDVTKEAQMVLSCIIRMGERFGKTMVAQVLAGSKNKKVTENGFQQLSTYGILKKRSIADISDFIEFLIADEYIKMS
DGTYPVLFVANKGRNVLLGREAVMRKEKMQTNQIVKDDELFERLRALRRKLAQEQGVPPFVVFSDETLREMSGKVPLTDE
ELLSVKGVGEQKRVKYGAVFLQELQAYKTEKEA

Specific function: Probable DNA helicase. Required for DNA repair and intramolecular recombination; probably has overlapping function with recS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Localized throughout the nucleoid in the presence or absence of DNA double- strand breaks [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=638, Percent_Identity=33.5423197492163, Blast_Score=312, Evalue=5e-85,
Organism=Homo sapiens, GI110735439, Length=525, Percent_Identity=35.4285714285714, Blast_Score=295, Evalue=6e-80,
Organism=Homo sapiens, GI169218196, Length=525, Percent_Identity=35.4285714285714, Blast_Score=295, Evalue=8e-80,
Organism=Homo sapiens, GI14591902, Length=442, Percent_Identity=37.3303167420815, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI14591904, Length=442, Percent_Identity=37.3303167420815, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI148612816, Length=427, Percent_Identity=37.2365339578454, Blast_Score=268, Evalue=2e-71,
Organism=Homo sapiens, GI51242943, Length=397, Percent_Identity=38.2871536523929, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI51242947, Length=397, Percent_Identity=38.2871536523929, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI284005309, Length=381, Percent_Identity=33.8582677165354, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI262118318, Length=404, Percent_Identity=25, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI216548263, Length=402, Percent_Identity=24.8756218905473, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI262231852, Length=402, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI222352149, Length=357, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI13518015, Length=402, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994977, Length=596, Percent_Identity=39.9328859060403, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1787016, Length=356, Percent_Identity=23.0337078651685, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=646, Percent_Identity=30.3405572755418, Blast_Score=297, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI71987993, Length=519, Percent_Identity=33.9113680154143, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71987997, Length=519, Percent_Identity=33.9113680154143, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI32564293, Length=480, Percent_Identity=36.4583333333333, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17552866, Length=456, Percent_Identity=32.6754385964912, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI71987143, Length=360, Percent_Identity=23.8888888888889, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71995724, Length=363, Percent_Identity=22.5895316804408, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507121, Length=363, Percent_Identity=22.3140495867769, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=505, Percent_Identity=34.4554455445545, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6324217, Length=332, Percent_Identity=25.3012048192771, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321360, Length=354, Percent_Identity=23.728813559322, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324778, Length=362, Percent_Identity=23.2044198895028, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646066, Length=637, Percent_Identity=32.6530612244898, Blast_Score=315, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24664226, Length=510, Percent_Identity=33.7254901960784, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI62472181, Length=426, Percent_Identity=36.8544600938967, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24664230, Length=426, Percent_Identity=36.8544600938967, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI21358123, Length=365, Percent_Identity=37.5342465753425, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24584399, Length=356, Percent_Identity=26.123595505618, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355075, Length=367, Percent_Identity=25.6130790190736, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17977678, Length=394, Percent_Identity=23.8578680203046, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66843; Mature: 66843

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKAEALLQHYFGYPSLRPGQKKAIQSVVSEKRDTACIMPTGGGKSICYQIPALLMEGT
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCC
TIVISPLISLMKDQVDALNQLGIQAAYVNSSLGHNEIAERLSVFKEGGYKLFYVTPERLT
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCC
SPEFIRAISHIHIPLVAIDEAHCISQWGHDFRPSYRHIEGFLNSLGTRPVVLALTATATP
CHHHHHHHHHHCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCC
EVHEDICTQLGIEKENTVFTGFSRDNLTFKILKGENRDRFIESYVEKNRSEAGIIYTATR
HHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECH
KEAERISSRLSQKGIAAGCYHGGMDDEERDRQQDLFLNDEISVMTATSAFGMGIDKSNIR
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCE
YVIHAQIPKNMESYYQEAGRAGRDGLDSECILLFSPQDIRLQRFLIEQSTEDEDIRAQDV
EEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHH
KKLRQMVDFCHTEGCLERFILSYFGEVPTEDCGRCGSCLDTRSITDVTKEAQMVLSCIIR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHH
MGERFGKTMVAQVLAGSKNKKVTENGFQQLSTYGILKKRSIADISDFIEFLIADEYIKMS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEC
DGTYPVLFVANKGRNVLLGREAVMRKEKMQTNQIVKDDELFERLRALRRKLAQEQGVPPF
CCCEEEEEEECCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCE
VVFSDETLREMSGKVPLTDEELLSVKGVGEQKRVKYGAVFLQELQAYKTEKEA
EEECCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLEKAEALLQHYFGYPSLRPGQKKAIQSVVSEKRDTACIMPTGGGKSICYQIPALLMEGT
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCC
TIVISPLISLMKDQVDALNQLGIQAAYVNSSLGHNEIAERLSVFKEGGYKLFYVTPERLT
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCC
SPEFIRAISHIHIPLVAIDEAHCISQWGHDFRPSYRHIEGFLNSLGTRPVVLALTATATP
CHHHHHHHHHHCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCC
EVHEDICTQLGIEKENTVFTGFSRDNLTFKILKGENRDRFIESYVEKNRSEAGIIYTATR
HHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECH
KEAERISSRLSQKGIAAGCYHGGMDDEERDRQQDLFLNDEISVMTATSAFGMGIDKSNIR
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCE
YVIHAQIPKNMESYYQEAGRAGRDGLDSECILLFSPQDIRLQRFLIEQSTEDEDIRAQDV
EEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHH
KKLRQMVDFCHTEGCLERFILSYFGEVPTEDCGRCGSCLDTRSITDVTKEAQMVLSCIIR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHH
MGERFGKTMVAQVLAGSKNKKVTENGFQQLSTYGILKKRSIADISDFIEFLIADEYIKMS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEC
DGTYPVLFVANKGRNVLLGREAVMRKEKMQTNQIVKDDELFERLRALRRKLAQEQGVPPF
CCCEEEEEEECCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCE
VVFSDETLREMSGKVPLTDEELLSVKGVGEQKRVKYGAVFLQELQAYKTEKEA
EEECCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9642195 [H]