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The map label for this gene is 52785740

Identifier: 52785740

GI number: 52785740

Start: 1936323

End: 1937801

Strand: Direct

Name: 52785740

Synonym: BLi01983

Alternate gene names: NA

Gene position: 1936323-1937801 (Clockwise)

Preceding gene: 52785739

Following gene: 52785741

Centisome position: 45.86

GC content: 47.6

Gene sequence:

>1479_bases
ATGATCCAAGCTCAAATTCTTTATAGAAAGCTGCAAGCGATCGGCAGAGAAGTCGGGGATAATTTGCAGCGAATCTCCCG
TTCTCCTGTGCTTTCGCAAGACCGGGCATTTGCTGCAGCGATTTTTACGAATGAGCTGAAAATCGCGGTTCAACATCAAT
ACGAGCCTGAACATTTGTTCGCATTAAAAGAAAGTGTCGAAAATCTGTTCGACTATTTTTCGTTTGATATCGCAGATGGA
GATGTGCTGCTGGTCGCAGATCCATACAGCGGCGGAACGAAAGGGCAGTCGCTCACCATGGCGGCGCCGCTATTCCTTGA
AGGGGAGCTCGTACTCTTCCCCGCTATCCGCGCTCAGATGATTGATTTGGCCGGCGAGTATCCGGGGGGCTTCCATCCCG
ATGCATTTGAAGTATGGCAGGAAAATATCAGAATTACTCCGGTTAAGCTTTATAAACAAGGAGTTCTGCAGACTGATATT
CTTCGTTTTTTATTATCAAACAGCCGGGTGCCCGCTTCTTTTAAAGCGGATCTTGAAGCCATGTATACATGTTTGCATGG
TGCCAAACAGCAATTGAAAACGTTTCTTGGCAGCTACGGTCAAAAAACAGTGGCCGCATCGATCAAAAGCATGTTTGAAT
ACAGCCAAAAAAGGGTTGAGCATCATGTCTCTCATCTGCCTGAAACAGAAATGAGCGCTGTCCAGGAGTTTGAAGTTACC
AAAGGGCACAAGAGTACAATTCATGTGCAAATTTCAAAGAAGGAGAATGCGGTTGAGATCGATTTGAGCGGATCGTCAGA
GCAGTCCGTAAAGCCGGTTAATTCACCTGCCGCTTTAACGAAGGCGTTTGCCGTTTGGCCGTTTCTTGCAAGGATTGCCG
ATGAAATACCGATCAATGAAGGAACGCTTCAACCTTTTCAAACGAAGACGAGGCCGGGAACGATTCTAGATCCGGAATTT
CCGGCAGCTACAGCACTAGCTCCAAGCATTACCGGACATTTCGTCGCTGCAGCGGTATTTAAAGCCATTCAAAACGGACA
AGGCACAAGTGAAGAATTTCCGCCGATTTATGGGCCAGGTCCGCAGGCCGTTTTTTATCCGGAGCTTGGCACAGGAGCCG
AAACAAAATCAATCGTTCTCGCACCCGGGTATCCTTCAGCTTCAAAAGGCTTCGGACCGCCTGCTTTATTTGGCCAACGG
ATGCTTGTCTCTGCGGAGGAATTGGAGCTTTACCACGGTTTTAAAATGGTTTCCCGGGAGTGGACGGACAATGGGGAGGA
AATGGAAGTGTCCCTGCTTAACCAGGAGGACGATATTTATTTCAACCTTCTTCTGCCTTTTAGCGAAAGGGGAAAATACG
GGTCTCTGTCAAGAACGGGAGACCATGACGAAACCTTTTATGAAAGCACGGTACACCAACATGTGAAAAAAGGCAACCTC
CTCGTCTTTACGTACTCTCAAAAGGAGGAGCAGCTATGA

Upstream 100 bases:

>100_bases
CCATTGTTGTTTACCCGGGACATGAGGCTCTAATCGATTCATACCGCAACTGTGTCATCGAAGTAAAGCATGCTCAACAG
GCGACAAGAGGTGGAAATGC

Downstream 100 bases:

>100_bases
TCAATCAGGACTTTATCTTATCACAGGTGGTCGGCGGTTCTCTTGATGCGGTTGCCAGGGAAATGAGCGCCACTGTCACG
AGAACGGCCCGTTCACCATT

Product: hypothetical protein

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MIQAQILYRKLQAIGREVGDNLQRISRSPVLSQDRAFAAAIFTNELKIAVQHQYEPEHLFALKESVENLFDYFSFDIADG
DVLLVADPYSGGTKGQSLTMAAPLFLEGELVLFPAIRAQMIDLAGEYPGGFHPDAFEVWQENIRITPVKLYKQGVLQTDI
LRFLLSNSRVPASFKADLEAMYTCLHGAKQQLKTFLGSYGQKTVAASIKSMFEYSQKRVEHHVSHLPETEMSAVQEFEVT
KGHKSTIHVQISKKENAVEIDLSGSSEQSVKPVNSPAALTKAFAVWPFLARIADEIPINEGTLQPFQTKTRPGTILDPEF
PAATALAPSITGHFVAAAVFKAIQNGQGTSEEFPPIYGPGPQAVFYPELGTGAETKSIVLAPGYPSASKGFGPPALFGQR
MLVSAEELELYHGFKMVSREWTDNGEEMEVSLLNQEDDIYFNLLLPFSERGKYGSLSRTGDHDETFYESTVHQHVKKGNL
LVFTYSQKEEQL

Sequences:

>Translated_492_residues
MIQAQILYRKLQAIGREVGDNLQRISRSPVLSQDRAFAAAIFTNELKIAVQHQYEPEHLFALKESVENLFDYFSFDIADG
DVLLVADPYSGGTKGQSLTMAAPLFLEGELVLFPAIRAQMIDLAGEYPGGFHPDAFEVWQENIRITPVKLYKQGVLQTDI
LRFLLSNSRVPASFKADLEAMYTCLHGAKQQLKTFLGSYGQKTVAASIKSMFEYSQKRVEHHVSHLPETEMSAVQEFEVT
KGHKSTIHVQISKKENAVEIDLSGSSEQSVKPVNSPAALTKAFAVWPFLARIADEIPINEGTLQPFQTKTRPGTILDPEF
PAATALAPSITGHFVAAAVFKAIQNGQGTSEEFPPIYGPGPQAVFYPELGTGAETKSIVLAPGYPSASKGFGPPALFGQR
MLVSAEELELYHGFKMVSREWTDNGEEMEVSLLNQEDDIYFNLLLPFSERGKYGSLSRTGDHDETFYESTVHQHVKKGNL
LVFTYSQKEEQL
>Mature_492_residues
MIQAQILYRKLQAIGREVGDNLQRISRSPVLSQDRAFAAAIFTNELKIAVQHQYEPEHLFALKESVENLFDYFSFDIADG
DVLLVADPYSGGTKGQSLTMAAPLFLEGELVLFPAIRAQMIDLAGEYPGGFHPDAFEVWQENIRITPVKLYKQGVLQTDI
LRFLLSNSRVPASFKADLEAMYTCLHGAKQQLKTFLGSYGQKTVAASIKSMFEYSQKRVEHHVSHLPETEMSAVQEFEVT
KGHKSTIHVQISKKENAVEIDLSGSSEQSVKPVNSPAALTKAFAVWPFLARIADEIPINEGTLQPFQTKTRPGTILDPEF
PAATALAPSITGHFVAAAVFKAIQNGQGTSEEFPPIYGPGPQAVFYPELGTGAETKSIVLAPGYPSASKGFGPPALFGQR
MLVSAEELELYHGFKMVSREWTDNGEEMEVSLLNQEDDIYFNLLLPFSERGKYGSLSRTGDHDETFYESTVHQHVKKGNL
LVFTYSQKEEQL

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=358, Percent_Identity=25.1396648044693, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI133901900, Length=363, Percent_Identity=24.2424242424242, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI133901902, Length=328, Percent_Identity=24.390243902439, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6322634, Length=370, Percent_Identity=23.7837837837838, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI45550492, Length=358, Percent_Identity=24.0223463687151, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 54534; Mature: 54534

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAQILYRKLQAIGREVGDNLQRISRSPVLSQDRAFAAAIFTNELKIAVQHQYEPEHLF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHH
ALKESVENLFDYFSFDIADGDVLLVADPYSGGTKGQSLTMAAPLFLEGELVLFPAIRAQM
HHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCEEEEECCEEECCCEEEEHHHHHHH
IDLAGEYPGGFHPDAFEVWQENIRITPVKLYKQGVLQTDILRFLLSNSRVPASFKADLEA
HHHCCCCCCCCCCCHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHH
MYTCLHGAKQQLKTFLGSYGQKTVAASIKSMFEYSQKRVEHHVSHLPETEMSAVQEFEVT
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
KGHKSTIHVQISKKENAVEIDLSGSSEQSVKPVNSPAALTKAFAVWPFLARIADEIPINE
CCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GTLQPFQTKTRPGTILDPEFPAATALAPSITGHFVAAAVFKAIQNGQGTSEEFPPIYGPG
CCCCCCCCCCCCCCEECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PQAVFYPELGTGAETKSIVLAPGYPSASKGFGPPALFGQRMLVSAEELELYHGFKMVSRE
CCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTDNGEEMEVSLLNQEDDIYFNLLLPFSERGKYGSLSRTGDHDETFYESTVHQHVKKGNL
CCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
LVFTYSQKEEQL
EEEEECCCCCCC
>Mature Secondary Structure
MIQAQILYRKLQAIGREVGDNLQRISRSPVLSQDRAFAAAIFTNELKIAVQHQYEPEHLF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHH
ALKESVENLFDYFSFDIADGDVLLVADPYSGGTKGQSLTMAAPLFLEGELVLFPAIRAQM
HHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCEEEEECCEEECCCEEEEHHHHHHH
IDLAGEYPGGFHPDAFEVWQENIRITPVKLYKQGVLQTDILRFLLSNSRVPASFKADLEA
HHHCCCCCCCCCCCHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHH
MYTCLHGAKQQLKTFLGSYGQKTVAASIKSMFEYSQKRVEHHVSHLPETEMSAVQEFEVT
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
KGHKSTIHVQISKKENAVEIDLSGSSEQSVKPVNSPAALTKAFAVWPFLARIADEIPINE
CCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GTLQPFQTKTRPGTILDPEFPAATALAPSITGHFVAAAVFKAIQNGQGTSEEFPPIYGPG
CCCCCCCCCCCCCCEECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PQAVFYPELGTGAETKSIVLAPGYPSASKGFGPPALFGQRMLVSAEELELYHGFKMVSRE
CCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTDNGEEMEVSLLNQEDDIYFNLLLPFSERGKYGSLSRTGDHDETFYESTVHQHVKKGNL
CCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
LVFTYSQKEEQL
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]