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The map label for this gene is codB [H]

Identifier: 52785738

GI number: 52785738

Start: 1932847

End: 1934196

Strand: Direct

Name: codB [H]

Synonym: BLi01981

Alternate gene names: 52785738

Gene position: 1932847-1934196 (Clockwise)

Preceding gene: 52785737

Following gene: 52785739

Centisome position: 45.77

GC content: 44.67

Gene sequence:

>1350_bases
ATGGAAAACAACAGTAAAAAACCTTCCTATACAAACGCTGATGATTTTGCTGTTACATCAGTCCCTGAAAATAAAAGAAA
ATCGATTTTTAACATTACGATTACAAGCTGTGCCTGGATCATCTCATTGTCGACGATTGTGACTGGAGGGGCATTAATCC
AGGGATTGAATTTTGCACATGCCGTTTTAGCAGCTGTCTTAGGCATGCTGATTCTTGCGGTATATGGCTTTTTTCAAGGA
GTAATGGGTGCGAAATACGGAATATCGACTACCGTTCTTGCCCGTCTGGCCTTTGGTCGCTACGGATCGAGCCTTTTTGG
AATTGTCTTGGCGCTGACGCTTGGAATCGGCTGGTTCGGCTGGCAGGTTGCTTTCTTTGGCACGACCATTTCCGAAATGT
TTCCGGGTGTTTGGCTTGCAAAGCCTGAGGTCGCCATCGTTTGGGGCGGCATTTTAATGATCCTTACCGCGTTTATAGGA
TATCGCGGGCTTGCCGCTTTAAGCTTTATCGCTGTACCTTTAGTCGTCATTTTTTCCATATGGGGAATCATAAGTGCTGT
CAATTACTCAGGAAGCTGGCATAACTTGCTGACATTTCACCCGACAGGGGATCCTCTGACGATATTTGCCGGAATTACAA
TTGTCGTTGGAAATGCTGCATTGGGCGCGGTTGTTTTTCCTGATGTGACGAGATATGCAAAAGGAGCGGTTTCAGGAGGA
ATAGGCGCTTCTGTAGGTTATTTCCTTGGAGGAGTGTTCTGTCTTGTTGCGGGAGCGGCAATGGCGATTGCCGCGAATGT
TCCGGATATCGGGTCAACACCGAATATTCCTGCCGCTATGAGCAAGCTTGGCCTGGGCTTTTTAGCATTTTTAATCATCG
TTTTTGCACAATGGACGACAAACGATAACAATTTGTATACCGGTTCGCTAGGGCTTCGCAATGTTGTGAACATTCCTAAG
AAAGCACTTGTGGCGATCATGGGCGTGATCGGAATTATCATTGCATTACTAGGTGTCCAAAATATGTTTGTGCCATTTTT
AACATTCTTAGGCTTGTATGTTCCGCCGATTGCGGGAGTCATGATCGCCGATCATTGGATCACAGCACCTGTCATCAAGA
AAAAACAATATCAATTCGGGGCTGGAACAACTTATTCGAAGCTGAATGTTGCGGCGATTCTTTCGGTGATCATCGGAGGT
TTTACCGCTTCAAAGATAACGTTCGGCATCGGGCCGATTAACTCTACTATACTTGCATTTTTGATTTATATCATCTTTAC
GTTTATTTTCACAAAATTAAATCTCCGTTACGAAATCGGAGAAGCGACAGAGGAATCGTCTGGTTTTTAA

Upstream 100 bases:

>100_bases
CTGAAAGGGCATGTACAATCGGCAATACGTTAAAGCGAGGGGTAACGATTGATACCAATATGGTGTAACAACCTACATGA
TGAAACGAAGGAGCATGAAA

Downstream 100 bases:

>100_bases
GCGGATAAGGAGGAAAGGTTTTCAATGATGAATGAAAAAAACCAATGGGTATTTGGAATTGATGTCGGCGGGACGTTTAC
AGATTTAGTGGCAGTCAACA

Product: hypothetical protein

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MENNSKKPSYTNADDFAVTSVPENKRKSIFNITITSCAWIISLSTIVTGGALIQGLNFAHAVLAAVLGMLILAVYGFFQG
VMGAKYGISTTVLARLAFGRYGSSLFGIVLALTLGIGWFGWQVAFFGTTISEMFPGVWLAKPEVAIVWGGILMILTAFIG
YRGLAALSFIAVPLVVIFSIWGIISAVNYSGSWHNLLTFHPTGDPLTIFAGITIVVGNAALGAVVFPDVTRYAKGAVSGG
IGASVGYFLGGVFCLVAGAAMAIAANVPDIGSTPNIPAAMSKLGLGFLAFLIIVFAQWTTNDNNLYTGSLGLRNVVNIPK
KALVAIMGVIGIIIALLGVQNMFVPFLTFLGLYVPPIAGVMIADHWITAPVIKKKQYQFGAGTTYSKLNVAAILSVIIGG
FTASKITFGIGPINSTILAFLIYIIFTFIFTKLNLRYEIGEATEESSGF

Sequences:

>Translated_449_residues
MENNSKKPSYTNADDFAVTSVPENKRKSIFNITITSCAWIISLSTIVTGGALIQGLNFAHAVLAAVLGMLILAVYGFFQG
VMGAKYGISTTVLARLAFGRYGSSLFGIVLALTLGIGWFGWQVAFFGTTISEMFPGVWLAKPEVAIVWGGILMILTAFIG
YRGLAALSFIAVPLVVIFSIWGIISAVNYSGSWHNLLTFHPTGDPLTIFAGITIVVGNAALGAVVFPDVTRYAKGAVSGG
IGASVGYFLGGVFCLVAGAAMAIAANVPDIGSTPNIPAAMSKLGLGFLAFLIIVFAQWTTNDNNLYTGSLGLRNVVNIPK
KALVAIMGVIGIIIALLGVQNMFVPFLTFLGLYVPPIAGVMIADHWITAPVIKKKQYQFGAGTTYSKLNVAAILSVIIGG
FTASKITFGIGPINSTILAFLIYIIFTFIFTKLNLRYEIGEATEESSGF
>Mature_449_residues
MENNSKKPSYTNADDFAVTSVPENKRKSIFNITITSCAWIISLSTIVTGGALIQGLNFAHAVLAAVLGMLILAVYGFFQG
VMGAKYGISTTVLARLAFGRYGSSLFGIVLALTLGIGWFGWQVAFFGTTISEMFPGVWLAKPEVAIVWGGILMILTAFIG
YRGLAALSFIAVPLVVIFSIWGIISAVNYSGSWHNLLTFHPTGDPLTIFAGITIVVGNAALGAVVFPDVTRYAKGAVSGG
IGASVGYFLGGVFCLVAGAAMAIAANVPDIGSTPNIPAAMSKLGLGFLAFLIIVFAQWTTNDNNLYTGSLGLRNVVNIPK
KALVAIMGVIGIIIALLGVQNMFVPFLTFLGLYVPPIAGVMIADHWITAPVIKKKQYQFGAGTTYSKLNVAAILSVIIGG
FTASKITFGIGPINSTILAFLIYIIFTFIFTKLNLRYEIGEATEESSGF

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=422, Percent_Identity=32.7014218009479, Blast_Score=158, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 47451; Mature: 47451

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNSKKPSYTNADDFAVTSVPENKRKSIFNITITSCAWIISLSTIVTGGALIQGLNFAH
CCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHH
AVLAAVLGMLILAVYGFFQGVMGAKYGISTTVLARLAFGRYGSSLFGIVLALTLGIGWFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHH
WQVAFFGTTISEMFPGVWLAKPEVAIVWGGILMILTAFIGYRGLAALSFIAVPLVVIFSI
HHHHHHHCCHHHHCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIISAVNYSGSWHNLLTFHPTGDPLTIFAGITIVVGNAALGAVVFPDVTRYAKGAVSGG
HHHHHHHCCCCCCCCEEEECCCCCCEEEEECEEHEECCCHHCHHHCHHHHHHHHHHCCCC
IGASVGYFLGGVFCLVAGAAMAIAANVPDIGSTPNIPAAMSKLGLGFLAFLIIVFAQWTT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NDNNLYTGSLGLRNVVNIPKKALVAIMGVIGIIIALLGVQNMFVPFLTFLGLYVPPIAGV
CCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIADHWITAPVIKKKQYQFGAGTTYSKLNVAAILSVIIGGFTASKITFGIGPINSTILAF
HHHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHHHHHH
LIYIIFTFIFTKLNLRYEIGEATEESSGF
HHHHHHHHHHHHHCCEEECCCCCCCCCCC
>Mature Secondary Structure
MENNSKKPSYTNADDFAVTSVPENKRKSIFNITITSCAWIISLSTIVTGGALIQGLNFAH
CCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHH
AVLAAVLGMLILAVYGFFQGVMGAKYGISTTVLARLAFGRYGSSLFGIVLALTLGIGWFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHH
WQVAFFGTTISEMFPGVWLAKPEVAIVWGGILMILTAFIGYRGLAALSFIAVPLVVIFSI
HHHHHHHCCHHHHCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIISAVNYSGSWHNLLTFHPTGDPLTIFAGITIVVGNAALGAVVFPDVTRYAKGAVSGG
HHHHHHHCCCCCCCCEEEECCCCCCEEEEECEEHEECCCHHCHHHCHHHHHHHHHHCCCC
IGASVGYFLGGVFCLVAGAAMAIAANVPDIGSTPNIPAAMSKLGLGFLAFLIIVFAQWTT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NDNNLYTGSLGLRNVVNIPKKALVAIMGVIGIIIALLGVQNMFVPFLTFLGLYVPPIAGV
CCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIADHWITAPVIKKKQYQFGAGTTYSKLNVAAILSVIIGGFTASKITFGIGPINSTILAF
HHHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHHHHHH
LIYIIFTFIFTKLNLRYEIGEATEESSGF
HHHHHHHHHHHHHCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]