The gene/protein map for NC_010468 is currently unavailable.
Definition Bacillus licheniformis ATCC 14580, complete genome.
Accession NC_006322
Length 4,222,645

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 52785670

GI number: 52785670

Start: 1872430

End: 1873161

Strand: Direct

Name: fabG [H]

Synonym: BLi01911

Alternate gene names: 52785670

Gene position: 1872430-1873161 (Clockwise)

Preceding gene: 52785669

Following gene: 52785671

Centisome position: 44.34

GC content: 51.78

Gene sequence:

>732_bases
ATGACAAAACTCGCTCTCATCACCGGCGCAAGCGGCGGAATCGGGCAAAGCATCAGCGAAAAGCTTGCGCAAAACGGGTA
TGATCTTCTCCTCCATTATCATACAAATGAGAAGGCGGCCGCTTCACTTGCAGAAAGGCTGTCACATACATACGGCATTC
ACGCTGAAATCATTCACGGCGACCTGTCCGACCCCGGAGGTGCAAAAACCGTTTCCGCTTCCATCGGCGGACGGGCGCTA
GACGGCATCGTCTTGAACAGCGGACAAAGCTTCCGCGGGCTTGTGACAGATATGACCGATGAAGCTGTACAGGACATGGT
GCAGCTCCATGTCTCAAGCCCGTTTCTATTAACGAGGAATCTGCTTCCGGCGATGATCAGGAAAAAGTCCGGCGCTATTG
TAGCCGTCAGCTCTATTTGGGGTGAGACAGGGGCGTCGTGCGAAGTTTTATACAGCATGACAAAAGGCGCGCAAAATGTG
TTTGTCAAAGCCCTTGCAAAAGAGCTTGCGCCGAGCGGCATCAGAGTCAACGCTGTTTCTCCGGGCGCTGTAAAAACAAA
GATGATGAGCTCATTTTCAAAAGAGGAAGAAGAGATGATCGCCGATGAGATTCCGATGGGAAGGCTCGCCGAAGCCGAAG
AGGTTGCAGACGCCGTCTTGTTTCTGCTCTCGGCGAAAGCATCTTATATCACGGGTCAAATTTTGTCAGTTAATGGCGGC
TGGCATTGTTAA

Upstream 100 bases:

>100_bases
TCCAAAATCATAAAGCAAGGTCTGAAAGTTCAGCGTGCAGGGATATTTCCGATGCACGCTGAACCTTTCTTCTTTTTTAA
CGGAAAGGTGGAAATATGGT

Downstream 100 bases:

>100_bases
AAACATGTATAGTTTACGATTCCCAAGAGAATAATAAGGCTGTAACTTCAAGAGAATGGAGGGGCCTGATATGTCCGTAC
TGGATAATTGGGATCAGTGG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHGDLSDPGGAKTVSASIGGRAL
DGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRNLLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNV
FVKALAKELAPSGIRVNAVSPGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG
WHC

Sequences:

>Translated_243_residues
MTKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHGDLSDPGGAKTVSASIGGRAL
DGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRNLLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNV
FVKALAKELAPSGIRVNAVSPGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG
WHC
>Mature_242_residues
TKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHGDLSDPGGAKTVSASIGGRALD
GIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRNLLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNVF
VKALAKELAPSGIRVNAVSPGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGGW
HC

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=32.2314049586777, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=34.5381526104418, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=31.4285714285714, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=28.6307053941909, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=27.3469387755102, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503301, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI59889578, Length=170, Percent_Identity=33.5294117647059, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371731, Length=197, Percent_Identity=27.4111675126904, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.1044176706827, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=25.4901960784314, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=29.2307692307692, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=27.3743016759777, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=36.0655737704918, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=35.1020408163265, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=36.4705882352941, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.4285714285714, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=25.5144032921811, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=26.9387755102041, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786812, Length=171, Percent_Identity=32.1637426900585, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=24.5833333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787526, Length=215, Percent_Identity=28.3720930232558, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=26.3681592039801, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=34.8178137651822, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=35.0806451612903, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=34.9397590361446, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=31.6872427983539, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.520325203252, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=32.1705426356589, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=30.2040816326531, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=28.3400809716599, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=32.183908045977, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=31.4176245210728, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=27.9352226720648, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=27.9352226720648, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=31.1284046692607, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=30.7407407407407, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.2134831460674, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.4615384615385, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=30.2238805970149, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=29.0697674418605, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=29.0441176470588, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25152911, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=27.7992277992278, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=206, Percent_Identity=23.3009708737864, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=27.9693486590038, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=28.0769230769231, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=27.8388278388278, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=25.2830188679245, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=166, Percent_Identity=27.710843373494, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=213, Percent_Identity=30.5164319248826, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=29.6, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.9397590361446, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=34.1463414634146, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=33.6032388663968, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.5220883534137, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=32.5301204819277, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.6, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644337, Length=116, Percent_Identity=39.6551724137931, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=28.3422459893048, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=26.6094420600858, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 25575; Mature: 25443

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHG
CCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC
DLSDPGGAKTVSASIGGRALDGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRN
CCCCCCCCEEEEECCCCCEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNVFVKALAKELAPSGIRVNAVS
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECC
PGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEEECCC
WHC
CCC
>Mature Secondary Structure 
TKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHG
CEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC
DLSDPGGAKTVSASIGGRALDGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRN
CCCCCCCCEEEEECCCCCEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNVFVKALAKELAPSGIRVNAVS
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECC
PGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEEECCC
WHC
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]