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The map label for this gene is fabD [H]

Identifier: 52785570

GI number: 52785570

Start: 1769359

End: 1770318

Strand: Direct

Name: fabD [H]

Synonym: BLi01811

Alternate gene names: 52785570

Gene position: 1769359-1770318 (Clockwise)

Preceding gene: 52785569

Following gene: 52785571

Centisome position: 41.9

GC content: 50.42

Gene sequence:

>960_bases
ATGGGCAAGATTGCTTTTCTATTCCCGGGCCAAGGTTCGCAGCATATCGGCATGGGACACGAATTGTATGAAAAAGAACC
GAATGCGAAGAAGATTTTTGAAGAAGCGGATCAAACGCTTGAAACAAAACTGAGCACCCTCATGTTTGAAGGGGATGCAA
AGGAACTGACGCTTACATACAACGCGCAGCCAAGCCTTTTAACGGCGAGCATCGCAGCGCTTGAAAAACTGAAGGAATAC
GGCATTAAAGCCGACTATGCGGCAGGTCACAGCCTCGGCGAATACAGCGCATTGGTCGCTGCCGGCGCCTTGTCGTTTAA
AGATGCGGTTTATGCCGTCAGAAAGCGCGGCGAATTCATGAATGAAGCCGTGCCGGCGGGAGAAGGCGCGATGGCGGCCA
TTCTCGGCATGGACAGCCAGGCGCTGAAAGAAGTGACGGACAAAATTTCCGAAGAAGGAAACCTTGTTCAGCTCGCCAAT
TTGAACTGCCCTGGGCAAATCGTCATCTCGGGAACAGCTAAAGGCGTGGAGCTCGCTTCAGAGCTTGCGAAAGAAAAGGG
CGCAAAACGCGCGATTCCTCTCGAAGTCAGCGGGCCGTTCCATTCTGAGCTGATGAAGCCGGCAGCTGATAAGCTTCGTG
AAGTTCTTGATGCGTGCACGATCAACGACGCAGCCATTCCGGTCGTCTCCAACGTAACGGCCGACTTTGTAACGGATAAA
GACGACATTAAGAATAAACTGATTGAACAGCTGTATTCCCCTGTACGCTTTGAAGAAACAATCAGCCGCCTGATTGACGA
AGGCGTCACGACCTTCATTGAAATCGGTCCCGGAAAGGTTTTGTCAGGGCTTGTGAAGAAAGTGAACCGCAGAGTCAAAA
CGATTGCTGTATCAGACCCGAACACAATTGAACTTGCCGTTCAAACGTTGAAGGAGGAAAACGAAAATGCTGGAAAATAA

Upstream 100 bases:

>100_bases
CGATCCGCCAGGCCAGAGAGATGGTCAGCCAAAATGTCGCGGCATTTATCGAAGAAAAAATTCAACAAAAAGCAGATGAA
TAGTCTGGAGGTTTTAACAC

Downstream 100 bases:

>100_bases
AACAGCCGTTGTGACAGGAGCCTCAAGAGGAATCGGCCGCGCGATCGCCCTGGACCTGGCGAAAAACGGAGCAAATGTCG
TCGTCAACTACGCGGGAAAT

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MGKIAFLFPGQGSQHIGMGHELYEKEPNAKKIFEEADQTLETKLSTLMFEGDAKELTLTYNAQPSLLTASIAALEKLKEY
GIKADYAAGHSLGEYSALVAAGALSFKDAVYAVRKRGEFMNEAVPAGEGAMAAILGMDSQALKEVTDKISEEGNLVQLAN
LNCPGQIVISGTAKGVELASELAKEKGAKRAIPLEVSGPFHSELMKPAADKLREVLDACTINDAAIPVVSNVTADFVTDK
DDIKNKLIEQLYSPVRFEETISRLIDEGVTTFIEIGPGKVLSGLVKKVNRRVKTIAVSDPNTIELAVQTLKEENENAGK

Sequences:

>Translated_319_residues
MGKIAFLFPGQGSQHIGMGHELYEKEPNAKKIFEEADQTLETKLSTLMFEGDAKELTLTYNAQPSLLTASIAALEKLKEY
GIKADYAAGHSLGEYSALVAAGALSFKDAVYAVRKRGEFMNEAVPAGEGAMAAILGMDSQALKEVTDKISEEGNLVQLAN
LNCPGQIVISGTAKGVELASELAKEKGAKRAIPLEVSGPFHSELMKPAADKLREVLDACTINDAAIPVVSNVTADFVTDK
DDIKNKLIEQLYSPVRFEETISRLIDEGVTTFIEIGPGKVLSGLVKKVNRRVKTIAVSDPNTIELAVQTLKEENENAGK
>Mature_318_residues
GKIAFLFPGQGSQHIGMGHELYEKEPNAKKIFEEADQTLETKLSTLMFEGDAKELTLTYNAQPSLLTASIAALEKLKEYG
IKADYAAGHSLGEYSALVAAGALSFKDAVYAVRKRGEFMNEAVPAGEGAMAAILGMDSQALKEVTDKISEEGNLVQLANL
NCPGQIVISGTAKGVELASELAKEKGAKRAIPLEVSGPFHSELMKPAADKLREVLDACTINDAAIPVVSNVTADFVTDKD
DIKNKLIEQLYSPVRFEETISRLIDEGVTTFIEIGPGKVLSGLVKKVNRRVKTIAVSDPNTIELAVQTLKEENENAGK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=33.1103678929766, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=39.2523364485981, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=44.6601941747573, Blast_Score=244, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=30.3754266211604, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.4915254237288, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.8803986710963, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34283; Mature: 34151

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIAFLFPGQGSQHIGMGHELYEKEPNAKKIFEEADQTLETKLSTLMFEGDAKELTLTY
CCEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEE
NAQPSLLTASIAALEKLKEYGIKADYAAGHSLGEYSALVAAGALSFKDAVYAVRKRGEFM
CCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEAVPAGEGAMAAILGMDSQALKEVTDKISEEGNLVQLANLNCPGQIVISGTAKGVELAS
HHHCCCCCCCEEHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHH
ELAKEKGAKRAIPLEVSGPFHSELMKPAADKLREVLDACTINDAAIPVVSNVTADFVTDK
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCH
DDIKNKLIEQLYSPVRFEETISRLIDEGVTTFIEIGPGKVLSGLVKKVNRRVKTIAVSDP
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHEEEEECCC
NTIELAVQTLKEENENAGK
CHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKIAFLFPGQGSQHIGMGHELYEKEPNAKKIFEEADQTLETKLSTLMFEGDAKELTLTY
CEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEE
NAQPSLLTASIAALEKLKEYGIKADYAAGHSLGEYSALVAAGALSFKDAVYAVRKRGEFM
CCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEAVPAGEGAMAAILGMDSQALKEVTDKISEEGNLVQLANLNCPGQIVISGTAKGVELAS
HHHCCCCCCCEEHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHH
ELAKEKGAKRAIPLEVSGPFHSELMKPAADKLREVLDACTINDAAIPVVSNVTADFVTDK
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCH
DDIKNKLIEQLYSPVRFEETISRLIDEGVTTFIEIGPGKVLSGLVKKVNRRVKTIAVSDP
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHEEEEECCC
NTIELAVQTLKEENENAGK
CHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]