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The map label for this gene is recG [H]

Identifier: 52785567

GI number: 52785567

Start: 1765600

End: 1767648

Strand: Direct

Name: recG [H]

Synonym: BLi01808

Alternate gene names: 52785567

Gene position: 1765600-1767648 (Clockwise)

Preceding gene: 52785566

Following gene: 52785568

Centisome position: 41.81

GC content: 50.61

Gene sequence:

>2049_bases
GTGGAACACAATCTGCAACTTAGTATATCTGTTATAAAAGGCGTCGGGACGGAAACGGAAAAAACGTTGAACGAGCTCGG
AATCTATACGGTTCTCGATCTTTTAAACTACTTCCCGTACCGATATGACGATTATGAATTGCGCGATTTGGAAGATGTGG
CACACGATGAACGAGTGACGGTGGAAGGGAAGGTTCACAGCGAGCCTTCTCTTGCCTATTACGGGAAAAAGCGGAGCCGT
CTCACGTTCCGGCTTTTGGTCGGGAACTATTTGATCACAGCGGTTTGCTTTAACAGGCCTTATTTGAAAAAAAAGCTTGC
GATCGGCTCGATTGTTACCGTAACCGGAAAATGGGACAAGCACAGACAATCCGTGATGGTGCAAGAGCTGAAAAACGGGC
CGCACCAGGGTGATCAGTCGATTGAACCCGTATACTCCGTCAAAGAAAACATCACCGTAAAGACGATGAGGAAATTGATT
CAGGAAGCTGTCCGCAGCCATTTGCCGTTTGCCGAAGATCCTCTTCCGGAAAAGCTTCGGACCGCCTACAAACTTCTGTC
TTACCAGGAGGCGGTAAAGGCGATGCACAAGCCCGAGTCGAGGGAAGCTTTAAAGCATGCGCGGCGCCGTTTTGTATATG
AGGAATTTTTGCTGTTTCAGCTGAAAATGCAGGCTTTGCGAAAGTTCGAGCGGGAAGCGTCCGACGGAATCAGCCACACC
TTTCGGCTCGAAGACGTCAATTCGTTTGTCAAAAGCCTTCCGTTTCCTTTGACAAACGCGCAGGCGAAAGCGCTCGACGA
CATATTAAGGGACATGGCTTCAGGGTATAAAATGAATCGGCTTTTGCAAGGAGACGTCGGTTCAGGCAAAACAGCCGTCG
CCGCGATTGCGCTATACGCCTCGCTGCTTTCCGGATTCCAGGGGGCGATGATGGTGCCGACCGAAATACTGGCGGAACAG
CACGCCGATTCGCTTGTATCCCTCTTTGAGCAGCACGACGTCAATGTGGCGCTTTTAACAAGCTCTGTGAAAGGGAAAAG
GAGAAGAGAGCTTTTAGAAAGATTAAAAGAAGGAGAAATTGATATTTTGGTGGGGACGCACGCCCTTATTCAGGACGATG
TCCACTTTAAACAGCTCGGGCTCGTGATCACCGATGAACAGCACCGCTTCGGCGTCGAGCAAAGAAAAAAACTGAGAAGC
AAAGGGAAAGATCCCGATGTCTTGTTTATGACGGCGACGCCGATTCCGAGAACACTGGCGATCACGGTTTTCGGGGAAAT
GGATGTGTCCGTCATCGATGAAATGCCGGCTGGGCGAAAGCGGATCGAGACGTATTGGGTAAAGCACGACATGCTCGAAC
GGATTCTCGCGTTTATCGATAAAGAACTGAAAAAAGGCAGACAGGCGTATGTGATCTGTCCCTTGATTGAAGAGTCGGAC
AAGCTCGACGTTCAAAATGCAATTGATGTGCACAGCATGCTGACTCATGCCTTCAGGGGAAGATGGCAGATCGGTCTCAT
GCACGGAAAGCTGTCAAATGACGAGAAAGAACAGGTAATGAGGCAGTTCAGCAAAAACGAATGCCAGATTCTCGTTTCCA
CAACCGTCGTTGAAGTCGGGGTAAACGTTCCGAATGCGACGGTCATGCTGATCTATGATGCCGACCGGTTCGGTCTTTCC
CAGCTGCATCAGCTTCGCGGCCGGGTCGGACGGGGCGATCACCAGTCGTATTGCATCCTGATGGCAGACCCGAAATCTGA
GACGGGAAAAGAGCGCATGAGCATCATGTCTGAGACGACGGACGGCTTTGAGCTTTCTGAAAAAGATCTTGAACTCAGAG
GGCCCGGGGACTTTTTCGGCAAGAAACAGAGCGGGATGCCGGAGTTTAAAGTCGCCGACATGGTTCACGACTACCGCGCG
CTGGAAACGGCAAGAAGAGACGCTGCAGAACTTGTCTCTTCAAAAGCGTTCTGGACGGATGCCGAATATAAAAGCCTGCG
GGAACACTTGCAAAACAGCGGGGTTATGGACGGAGAGAAGCTGAGCTGA

Upstream 100 bases:

>100_bases
ATGCCGACGGCACTGAGGGAAACAGGCCGGGGCGGTCTTGCCGCAACACCGACGGGCAAAGAATTGGAGAAAAAAATATT
CGGAGGAGCGTCAGCTGCAC

Downstream 100 bases:

>100_bases
TCTGAAGTCCAGCTAAAATTTATCGTCGGCGGGTAAAGAAAGATTGCATTCCAATCTATGAAATTATATACTACTATTAG
TACCTAGTCATAATTGCGCG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MEHNLQLSISVIKGVGTETEKTLNELGIYTVLDLLNYFPYRYDDYELRDLEDVAHDERVTVEGKVHSEPSLAYYGKKRSR
LTFRLLVGNYLITAVCFNRPYLKKKLAIGSIVTVTGKWDKHRQSVMVQELKNGPHQGDQSIEPVYSVKENITVKTMRKLI
QEAVRSHLPFAEDPLPEKLRTAYKLLSYQEAVKAMHKPESREALKHARRRFVYEEFLLFQLKMQALRKFEREASDGISHT
FRLEDVNSFVKSLPFPLTNAQAKALDDILRDMASGYKMNRLLQGDVGSGKTAVAAIALYASLLSGFQGAMMVPTEILAEQ
HADSLVSLFEQHDVNVALLTSSVKGKRRRELLERLKEGEIDILVGTHALIQDDVHFKQLGLVITDEQHRFGVEQRKKLRS
KGKDPDVLFMTATPIPRTLAITVFGEMDVSVIDEMPAGRKRIETYWVKHDMLERILAFIDKELKKGRQAYVICPLIEESD
KLDVQNAIDVHSMLTHAFRGRWQIGLMHGKLSNDEKEQVMRQFSKNECQILVSTTVVEVGVNVPNATVMLIYDADRFGLS
QLHQLRGRVGRGDHQSYCILMADPKSETGKERMSIMSETTDGFELSEKDLELRGPGDFFGKKQSGMPEFKVADMVHDYRA
LETARRDAAELVSSKAFWTDAEYKSLREHLQNSGVMDGEKLS

Sequences:

>Translated_682_residues
MEHNLQLSISVIKGVGTETEKTLNELGIYTVLDLLNYFPYRYDDYELRDLEDVAHDERVTVEGKVHSEPSLAYYGKKRSR
LTFRLLVGNYLITAVCFNRPYLKKKLAIGSIVTVTGKWDKHRQSVMVQELKNGPHQGDQSIEPVYSVKENITVKTMRKLI
QEAVRSHLPFAEDPLPEKLRTAYKLLSYQEAVKAMHKPESREALKHARRRFVYEEFLLFQLKMQALRKFEREASDGISHT
FRLEDVNSFVKSLPFPLTNAQAKALDDILRDMASGYKMNRLLQGDVGSGKTAVAAIALYASLLSGFQGAMMVPTEILAEQ
HADSLVSLFEQHDVNVALLTSSVKGKRRRELLERLKEGEIDILVGTHALIQDDVHFKQLGLVITDEQHRFGVEQRKKLRS
KGKDPDVLFMTATPIPRTLAITVFGEMDVSVIDEMPAGRKRIETYWVKHDMLERILAFIDKELKKGRQAYVICPLIEESD
KLDVQNAIDVHSMLTHAFRGRWQIGLMHGKLSNDEKEQVMRQFSKNECQILVSTTVVEVGVNVPNATVMLIYDADRFGLS
QLHQLRGRVGRGDHQSYCILMADPKSETGKERMSIMSETTDGFELSEKDLELRGPGDFFGKKQSGMPEFKVADMVHDYRA
LETARRDAAELVSSKAFWTDAEYKSLREHLQNSGVMDGEKLS
>Mature_682_residues
MEHNLQLSISVIKGVGTETEKTLNELGIYTVLDLLNYFPYRYDDYELRDLEDVAHDERVTVEGKVHSEPSLAYYGKKRSR
LTFRLLVGNYLITAVCFNRPYLKKKLAIGSIVTVTGKWDKHRQSVMVQELKNGPHQGDQSIEPVYSVKENITVKTMRKLI
QEAVRSHLPFAEDPLPEKLRTAYKLLSYQEAVKAMHKPESREALKHARRRFVYEEFLLFQLKMQALRKFEREASDGISHT
FRLEDVNSFVKSLPFPLTNAQAKALDDILRDMASGYKMNRLLQGDVGSGKTAVAAIALYASLLSGFQGAMMVPTEILAEQ
HADSLVSLFEQHDVNVALLTSSVKGKRRRELLERLKEGEIDILVGTHALIQDDVHFKQLGLVITDEQHRFGVEQRKKLRS
KGKDPDVLFMTATPIPRTLAITVFGEMDVSVIDEMPAGRKRIETYWVKHDMLERILAFIDKELKKGRQAYVICPLIEESD
KLDVQNAIDVHSMLTHAFRGRWQIGLMHGKLSNDEKEQVMRQFSKNECQILVSTTVVEVGVNVPNATVMLIYDADRFGLS
QLHQLRGRVGRGDHQSYCILMADPKSETGKERMSIMSETTDGFELSEKDLELRGPGDFFGKKQSGMPEFKVADMVHDYRA
LETARRDAAELVSSKAFWTDAEYKSLREHLQNSGVMDGEKLS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=671, Percent_Identity=38.8971684053651, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787357, Length=405, Percent_Identity=38.2716049382716, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77628; Mature: 77628

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHNLQLSISVIKGVGTETEKTLNELGIYTVLDLLNYFPYRYDDYELRDLEDVAHDERVT
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEE
VEGKVHSEPSLAYYGKKRSRLTFRLLVGNYLITAVCFNRPYLKKKLAIGSIVTVTGKWDK
EECCCCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCHH
HRQSVMVQELKNGPHQGDQSIEPVYSVKENITVKTMRKLIQEAVRSHLPFAEDPLPEKLR
HHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
TAYKLLSYQEAVKAMHKPESREALKHARRRFVYEEFLLFQLKMQALRKFEREASDGISHT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FRLEDVNSFVKSLPFPLTNAQAKALDDILRDMASGYKMNRLLQGDVGSGKTAVAAIALYA
EEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHH
SLLSGFQGAMMVPTEILAEQHADSLVSLFEQHDVNVALLTSSVKGKRRRELLERLKEGEI
HHHHCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCE
DILVGTHALIQDDVHFKQLGLVITDEQHRFGVEQRKKLRSKGKDPDVLFMTATPIPRTLA
EEEECCHHHHHCCCCHHHCCEEEECCHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEE
ITVFGEMDVSVIDEMPAGRKRIETYWVKHDMLERILAFIDKELKKGRQAYVICPLIEESD
EEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
KLDVQNAIDVHSMLTHAFRGRWQIGLMHGKLSNDEKEQVMRQFSKNECQILVSTTVVEVG
CCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEEC
VNVPNATVMLIYDADRFGLSQLHQLRGRVGRGDHQSYCILMADPKSETGKERMSIMSETT
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
DGFELSEKDLELRGPGDFFGKKQSGMPEFKVADMVHDYRALETARRDAAELVSSKAFWTD
CCCCCCCCCEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AEYKSLREHLQNSGVMDGEKLS
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEHNLQLSISVIKGVGTETEKTLNELGIYTVLDLLNYFPYRYDDYELRDLEDVAHDERVT
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEE
VEGKVHSEPSLAYYGKKRSRLTFRLLVGNYLITAVCFNRPYLKKKLAIGSIVTVTGKWDK
EECCCCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCHH
HRQSVMVQELKNGPHQGDQSIEPVYSVKENITVKTMRKLIQEAVRSHLPFAEDPLPEKLR
HHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
TAYKLLSYQEAVKAMHKPESREALKHARRRFVYEEFLLFQLKMQALRKFEREASDGISHT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FRLEDVNSFVKSLPFPLTNAQAKALDDILRDMASGYKMNRLLQGDVGSGKTAVAAIALYA
EEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHH
SLLSGFQGAMMVPTEILAEQHADSLVSLFEQHDVNVALLTSSVKGKRRRELLERLKEGEI
HHHHCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCE
DILVGTHALIQDDVHFKQLGLVITDEQHRFGVEQRKKLRSKGKDPDVLFMTATPIPRTLA
EEEECCHHHHHCCCCHHHCCEEEECCHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEE
ITVFGEMDVSVIDEMPAGRKRIETYWVKHDMLERILAFIDKELKKGRQAYVICPLIEESD
EEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
KLDVQNAIDVHSMLTHAFRGRWQIGLMHGKLSNDEKEQVMRQFSKNECQILVSTTVVEVG
CCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEEC
VNVPNATVMLIYDADRFGLSQLHQLRGRVGRGDHQSYCILMADPKSETGKERMSIMSETT
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
DGFELSEKDLELRGPGDFFGKKQSGMPEFKVADMVHDYRALETARRDAAELVSSKAFWTD
CCCCCCCCCEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AEYKSLREHLQNSGVMDGEKLS
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]