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The map label for this gene is ylbQ [H]

Identifier: 52785487

GI number: 52785487

Start: 1681155

End: 1682036

Strand: Direct

Name: ylbQ [H]

Synonym: BLi01728

Alternate gene names: 52785487

Gene position: 1681155-1682036 (Clockwise)

Preceding gene: 52785485

Following gene: 52785488

Centisome position: 39.81

GC content: 53.85

Gene sequence:

>882_bases
GTGAAAATCGGAGTCATCGGAGGAGGCTCGGTCGGCCTCCTTTTTGCATACTATTTTTCGTTCGGCCACGAAGTGACTGT
GATTGCGCGGAGAAAGGAACAGGCGGAAGCGATTGAAGAAAAGGGAATCCGCCTTCTTGAAGACGGGAAAGAGATGACCG
TGAACGCCAGGGGCGTGACTGAACTTGATCCGGACTGCGACCTTCTTTTTGTTGCCGTAAAGGAGCATCAGCTCGGAGCC
GTTCTGTCTGAGCTGGAGCAGGCGGCTCCTCTTGACATCATGTTCCTGCAAAATGGAATGGCGCATATTCCCGTGCTTGA
AAAATGGCAGACGGGCCACCGCATCTATACGGGATCTGTGGAACACGGAGCTGTCAGGGTGGATGACCGCACATTCCGGC
ACACGGGAAAAGGGGCCGTAAAATGGAGCGCGTTCCGAAGCCAATCCGCCGCCCGGCTGAAAAAAGAGCTCGCTTCGGTG
CATGAAGCGTTCCCTTTTATTTGGTCCGAAGACTGGTATAAGCCCCTCGCCGAAAAATTGATTGTCAATGCGTGCATCAA
TCCGCTGACGGCTCTTTTGCGGGTGAAAAACGGCGCGCTGCTTGAGGAGCCGATGTATGGGGCCTATATGAAGTTCGTCT
TTGAAGAAGCGAGCCGGATTTTGGAACTTGAAGATCGCCAGGCAGCGTGGGACCATGTTCTTTCCGTCTGCCGCCGGACG
AAAAGCAACACGTCCTCAATGCTTGCCGATGTGCTGGCAGAAAGAAAAACGGAAGCGGATGCGATCATCGGCTATCTGCT
GAAGCGGGCAAAAGAGTCAGGAGAGCCCGCCCCGCACCTTACCTTTTTATATCGCAGCATCAAGGCGCTTGAAAACGAAT
GA

Upstream 100 bases:

>100_bases
ATGAAGCGAAACGGTTCTGAATATTTGAAACAACTGACAAGTCAACGGCGAAAATTTCTGCTATGATATACAGTATATGA
AAAAATCAGGGTGTGAGAAT

Downstream 100 bases:

>100_bases
AGCTAAATCTTTTGACCGAATCGCGTAACGTGCTATACTCGTTTCGGATAGCTAACTATTTACTGGAGAAAGGAAGTTCT
AGAGATGCAGCTTACTGAAC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKIGVIGGGSVGLLFAYYFSFGHEVTVIARRKEQAEAIEEKGIRLLEDGKEMTVNARGVTELDPDCDLLFVAVKEHQLGA
VLSELEQAAPLDIMFLQNGMAHIPVLEKWQTGHRIYTGSVEHGAVRVDDRTFRHTGKGAVKWSAFRSQSAARLKKELASV
HEAFPFIWSEDWYKPLAEKLIVNACINPLTALLRVKNGALLEEPMYGAYMKFVFEEASRILELEDRQAAWDHVLSVCRRT
KSNTSSMLADVLAERKTEADAIIGYLLKRAKESGEPAPHLTFLYRSIKALENE

Sequences:

>Translated_293_residues
MKIGVIGGGSVGLLFAYYFSFGHEVTVIARRKEQAEAIEEKGIRLLEDGKEMTVNARGVTELDPDCDLLFVAVKEHQLGA
VLSELEQAAPLDIMFLQNGMAHIPVLEKWQTGHRIYTGSVEHGAVRVDDRTFRHTGKGAVKWSAFRSQSAARLKKELASV
HEAFPFIWSEDWYKPLAEKLIVNACINPLTALLRVKNGALLEEPMYGAYMKFVFEEASRILELEDRQAAWDHVLSVCRRT
KSNTSSMLADVLAERKTEADAIIGYLLKRAKESGEPAPHLTFLYRSIKALENE
>Mature_293_residues
MKIGVIGGGSVGLLFAYYFSFGHEVTVIARRKEQAEAIEEKGIRLLEDGKEMTVNARGVTELDPDCDLLFVAVKEHQLGA
VLSELEQAAPLDIMFLQNGMAHIPVLEKWQTGHRIYTGSVEHGAVRVDDRTFRHTGKGAVKWSAFRSQSAARLKKELASV
HEAFPFIWSEDWYKPLAEKLIVNACINPLTALLRVKNGALLEEPMYGAYMKFVFEEASRILELEDRQAAWDHVLSVCRRT
KSNTSSMLADVLAERKTEADAIIGYLLKRAKESGEPAPHLTFLYRSIKALENE

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=308, Percent_Identity=31.4935064935065, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32847; Mature: 32847

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVIGGGSVGLLFAYYFSFGHEVTVIARRKEQAEAIEEKGIRLLEDGKEMTVNARGVT
CEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCEEECCCCEEEEECCCCC
ELDPDCDLLFVAVKEHQLGAVLSELEQAAPLDIMFLQNGMAHIPVLEKWQTGHRIYTGSV
CCCCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCCCEEEECCC
EHGAVRVDDRTFRHTGKGAVKWSAFRSQSAARLKKELASVHEAFPFIWSEDWYKPLAEKL
CCCEEEECCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IVNACINPLTALLRVKNGALLEEPMYGAYMKFVFEEASRILELEDRQAAWDHVLSVCRRT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSNTSSMLADVLAERKTEADAIIGYLLKRAKESGEPAPHLTFLYRSIKALENE
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGVIGGGSVGLLFAYYFSFGHEVTVIARRKEQAEAIEEKGIRLLEDGKEMTVNARGVT
CEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCEEECCCCEEEEECCCCC
ELDPDCDLLFVAVKEHQLGAVLSELEQAAPLDIMFLQNGMAHIPVLEKWQTGHRIYTGSV
CCCCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCCCEEEECCC
EHGAVRVDDRTFRHTGKGAVKWSAFRSQSAARLKKELASVHEAFPFIWSEDWYKPLAEKL
CCCEEEECCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IVNACINPLTALLRVKNGALLEEPMYGAYMKFVFEEASRILELEDRQAAWDHVLSVCRRT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSNTSSMLADVLAERKTEADAIIGYLLKRAKESGEPAPHLTFLYRSIKALENE
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]