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The map label for this gene is ylaM [H]

Identifier: 52785460

GI number: 52785460

Start: 1655630

End: 1656559

Strand: Direct

Name: ylaM [H]

Synonym: BLi01700

Alternate gene names: 52785460

Gene position: 1655630-1656559 (Clockwise)

Preceding gene: 52785458

Following gene: 52785461

Centisome position: 39.21

GC content: 46.77

Gene sequence:

>930_bases
TTGAATTGCCGGCATAATAAGGAGCTCGAATATTTTGTCACAGAAGCGAAAAAAGTGACGGACAAAGGAAAGGTTGCATC
TTACATACCGGCTTTGGCCGAATTATCGGAGGACGATTTATCGGCGGCGGTCTACTTTACCGACGGGACTTGTATATCAG
CGGGGGATGTGGAAAAAGCATTCACTCTGCAAAGCATATCAAAAGTATTGTCGCTTGCCCTCGTTCTGATCGATCACGGA
CCGGAAAAAGTGTTTCATTACGTAGGACAAGAGCCGACTGGCGATCCGTTTAACTCCATCATCAAGCTTGAAACCGTCAA
CCCGGGGAAGCCGCTGAATCCGATGATAAACGCAGGAGCATTGGTGGTCACAAGCATGATTAAAGGAGAGACGAACGCTG
ATAAGATCGGGAGACTGCTTGATTTTATTAAAAAACTTGCAAACAACCGGAGCATTACCGTTTGCGGGAAGGTCGCCGAA
TCTGAATTTGAAACCTCGATGGTCAACAGGGCGATGTGCTATTACATGAAAGAGCACGGCATTTTTCAGGCTGAGGTTGA
GGATGTTATGGATGTATATACAAAACAGTGCGCCATTGAAATGAACAGCCTGGACCTGGCAAAAATCGGCTCTGTTTTTG
CTTTGAACGGCAAGCATCCCGAAACGGGAGAACAAATCATACCGAAGGATATCGCGAGAATTTGCAAGACATTTATGGTG
ACATGCGGAATGTATAATGCCAGCGGCGAATTCGCAATCAAAATCGGAATTCCCGCCAAAAGCGGGGTTTCAGGGGGCAT
CATGGGGCTATCCCCATACCGTTTCGGCATCGGCATCTTCGGGCCTTCGCTCGATGAAAAGGGAAACAGCATTGCCGGAA
TCCGGCTTTTAGAGCTATTATCTGCGAATTACAGCTTAAGCATTTTTTAA

Upstream 100 bases:

>100_bases
CAAAAAATTATAAGCGCTTTCTTTCGAATTGTCACTTCTCATAACAAAAGCCCTCTCGGGGAAAGATAACAGCAATGACG
CTCGGATGGAGGGAAAAAAC

Downstream 100 bases:

>100_bases
AACGTTAGCGGAAGCTTAAAAAGCGAGTCTTTGAAATACGGCGAAAGGACAGAAATAGCTTGCTTTTTTTCGGCTGAGGC
TTTATCATAAATAGAAGAAT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNCRHNKELEYFVTEAKKVTDKGKVASYIPALAELSEDDLSAAVYFTDGTCISAGDVEKAFTLQSISKVLSLALVLIDHG
PEKVFHYVGQEPTGDPFNSIIKLETVNPGKPLNPMINAGALVVTSMIKGETNADKIGRLLDFIKKLANNRSITVCGKVAE
SEFETSMVNRAMCYYMKEHGIFQAEVEDVMDVYTKQCAIEMNSLDLAKIGSVFALNGKHPETGEQIIPKDIARICKTFMV
TCGMYNASGEFAIKIGIPAKSGVSGGIMGLSPYRFGIGIFGPSLDEKGNSIAGIRLLELLSANYSLSIF

Sequences:

>Translated_309_residues
MNCRHNKELEYFVTEAKKVTDKGKVASYIPALAELSEDDLSAAVYFTDGTCISAGDVEKAFTLQSISKVLSLALVLIDHG
PEKVFHYVGQEPTGDPFNSIIKLETVNPGKPLNPMINAGALVVTSMIKGETNADKIGRLLDFIKKLANNRSITVCGKVAE
SEFETSMVNRAMCYYMKEHGIFQAEVEDVMDVYTKQCAIEMNSLDLAKIGSVFALNGKHPETGEQIIPKDIARICKTFMV
TCGMYNASGEFAIKIGIPAKSGVSGGIMGLSPYRFGIGIFGPSLDEKGNSIAGIRLLELLSANYSLSIF
>Mature_309_residues
MNCRHNKELEYFVTEAKKVTDKGKVASYIPALAELSEDDLSAAVYFTDGTCISAGDVEKAFTLQSISKVLSLALVLIDHG
PEKVFHYVGQEPTGDPFNSIIKLETVNPGKPLNPMINAGALVVTSMIKGETNADKIGRLLDFIKKLANNRSITVCGKVAE
SEFETSMVNRAMCYYMKEHGIFQAEVEDVMDVYTKQCAIEMNSLDLAKIGSVFALNGKHPETGEQIIPKDIARICKTFMV
TCGMYNASGEFAIKIGIPAKSGVSGGIMGLSPYRFGIGIFGPSLDEKGNSIAGIRLLELLSANYSLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=285, Percent_Identity=39.6491228070175, Blast_Score=194, Evalue=6e-50,
Organism=Homo sapiens, GI20336214, Length=281, Percent_Identity=36.6548042704626, Blast_Score=168, Evalue=7e-42,
Organism=Escherichia coli, GI1787804, Length=304, Percent_Identity=39.8026315789474, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1786693, Length=289, Percent_Identity=37.3702422145329, Blast_Score=205, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17507019, Length=308, Percent_Identity=37.3376623376623, Blast_Score=202, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17532727, Length=303, Percent_Identity=38.6138613861386, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI193204073, Length=296, Percent_Identity=37.5, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI193204075, Length=298, Percent_Identity=37.248322147651, Blast_Score=176, Evalue=9e-45,
Organism=Drosophila melanogaster, GI281363241, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24653162, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI281363239, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI116008307, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24653164, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24653158, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24653156, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24653166, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33503; Mature: 33503

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCRHNKELEYFVTEAKKVTDKGKVASYIPALAELSEDDLSAAVYFTDGTCISAGDVEKA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCHHH
FTLQSISKVLSLALVLIDHGPEKVFHYVGQEPTGDPFNSIIKLETVNPGKPLNPMINAGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHCEEEEEECCCCCCCCHHHCCCH
LVVTSMIKGETNADKIGRLLDFIKKLANNRSITVCGKVAESEFETSMVNRAMCYYMKEHG
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
IFQAEVEDVMDVYTKQCAIEMNSLDLAKIGSVFALNGKHPETGEQIIPKDIARICKTFMV
CCHHHHHHHHHHHHHHHHEECCCCCHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
TCGMYNASGEFAIKIGIPAKSGVSGGIMGLSPYRFGIGIFGPSLDEKGNSIAGIRLLELL
HHCCCCCCCCEEEEEECCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
SANYSLSIF
CCCCEEEEC
>Mature Secondary Structure
MNCRHNKELEYFVTEAKKVTDKGKVASYIPALAELSEDDLSAAVYFTDGTCISAGDVEKA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCHHH
FTLQSISKVLSLALVLIDHGPEKVFHYVGQEPTGDPFNSIIKLETVNPGKPLNPMINAGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHCEEEEEECCCCCCCCHHHCCCH
LVVTSMIKGETNADKIGRLLDFIKKLANNRSITVCGKVAESEFETSMVNRAMCYYMKEHG
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
IFQAEVEDVMDVYTKQCAIEMNSLDLAKIGSVFALNGKHPETGEQIIPKDIARICKTFMV
CCHHHHHHHHHHHHHHHHEECCCCCHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
TCGMYNASGEFAIKIGIPAKSGVSGGIMGLSPYRFGIGIFGPSLDEKGNSIAGIRLLELL
HHCCCCCCCCEEEEEECCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
SANYSLSIF
CCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]