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The map label for this gene is adeC

Identifier: 52785427

GI number: 52785427

Start: 1625659

End: 1627380

Strand: Direct

Name: adeC

Synonym: BLi01667

Alternate gene names: 52785427

Gene position: 1625659-1627380 (Clockwise)

Preceding gene: 52785426

Following gene: 52785430

Centisome position: 38.5

GC content: 50.12

Gene sequence:

>1722_bases
TTGGACAAAGAGATGTTCATTCGCCGGCTTGGCGCCGCCAGTCATCGCAAAAAAGCGGAAACTGTAATTAAAAACGGAAA
AATCATGGATGTTTTTAATCAGGAATGGTTGGAGACGGACATTGCCATCACAGACGGGGCCATCGTCGGCTTGGGCGAAT
ATGAGGGGGGAAATATCATTGACGCTGAGGGACAAATGATCGTTCCCGGCTTTATCGACGGTCATGTCCATATTGAGTCC
TCGATGGTGACGCCGCCCGAATTCGCTAAAGCGGTGATTCCCCACGGTGTGACAACCGTTGTCACCGATCCCCACGAAAT
CGCGAATGTCTCAGGTGTGAAGGGTCTTGAGTTCATGTTGGAGCAGGCTGAGATGACCAGGCTGAACATTTATTTTATGC
TCCCTTCTTGTGTGCCTGCGGCACCATTCGAAAAATCGGGTGCGATTTTGAACGCCGCGGATTTACATCCTTTTTACAGC
CGCGAAGAGGTGCTCGGGCTTGCGGAAGTGATGGACTATGTGGCCGTTGAAGCTGGAGAGCCGGATATGGTGCAAAAGCT
CATTGATGCCGATAAAGCGGGCAAGCGGATCGACGGGCATCTGGCCGGCTTGTCAGCCGGGTTTGTCAATGTCTACAGAG
CGGCGGGCGTGCTTACAGACCATGAGGTCACAACACCTGAAGAGGCGCTTGAACGAGTGAGAAGAGGGATGTACGTCATG
CTGAGAGAAGGTTCTGCGGCAAAGAATACGCGTCATGTTTTACCTGCGGTCAACGAGAAAAATGTGAGACGCTTCTTTTT
CTGTACGGATGATAAGCATCTGGACGAACTGGTCGATGAAGGAAGCATTAACTACCAGGTCAAGCTTGCCATTCAAGAGG
GGCTTGACCCGTTTCTCGCATATCAAATGGGCAGCCTGAATGCAGCGGAATGCTTCGGGTTAAAGACGAAGGGAGCGGTC
GCCCCGGGTTATGACGCAGATCTTCTTTTCATCAGCGATTTTGAGAACGTGAGCATTACAAAGACGATGATTAACGGCGT
GATCTGGAGCGGGACAGAGCAAAGCCAATCGACGGGCGGCAAAGCGGCATCCGGTCTGCTTCAATCTGTGCATCTGTCTG
ATTTACATGAGAACGATCTGCAAATTCCGATCGTTCAAGAGAATGAAATCAGGGTTATTGACATTATCCCCAATCAGCTC
GAAACAAAGCTGTCCCTGGCCAAGCCGAAAAGCGGAGCTTTTTTTCAGCCGGATCTGGAAAGCGATCTGTTGAAAATTGC
AGTGGTTGAGCGCCATCGCGGCGTTAAAGAAATCGGACTCGGCGTAGTCAGAGGCTTCGGTTTAAAAGAAGGCGCCATCG
CGACAACCATTTCTCATGATTCCCACAATTTAATCGCTGTCGGTACAAATGATCAAGACATTTTAAAAGCGATTGAACGC
CTCGGAGAAATCGGAGGAGGCCTCACCATTGCCAAAGGAGGGAAGGAGCTTCAATCCGTCGCACTGCCGATCGCCGGCCT
CTTGTCGGACAAACCGCTTGAGACGGTCAACGAAAGCTTGAAATCTCTCCACGCGGCAATAACAGAGACAGGATTTTCAG
GAGCGTTTAATCCTTTTCTGACGCTTTCTTTTTTAGCGCTTCCGGTCATTCCCGACATTAAAATGACAACGGAAGGATTG
TTTGATGTTAAAGCGTTCAGGCATATCCCGGTTCAACCATAA

Upstream 100 bases:

>100_bases
CACAGCCCGCGGTTTTTTTGATCTTTTCATTGACTGTTTCAAGCGATTCGGCTACGATATTGAACCATATACATATAAAA
AAGAGAGGGGACATATACCT

Downstream 100 bases:

>100_bases
AAAAACGGATGCACCCCGGTGCATCCGTTTTTTGCTGTATCCGCATCCGCGATTAGACTTCCATAATAATCGGAAGGATC
ATCGGCCGGCGTTTTGTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MDKEMFIRRLGAASHRKKAETVIKNGKIMDVFNQEWLETDIAITDGAIVGLGEYEGGNIIDAEGQMIVPGFIDGHVHIES
SMVTPPEFAKAVIPHGVTTVVTDPHEIANVSGVKGLEFMLEQAEMTRLNIYFMLPSCVPAAPFEKSGAILNAADLHPFYS
REEVLGLAEVMDYVAVEAGEPDMVQKLIDADKAGKRIDGHLAGLSAGFVNVYRAAGVLTDHEVTTPEEALERVRRGMYVM
LREGSAAKNTRHVLPAVNEKNVRRFFFCTDDKHLDELVDEGSINYQVKLAIQEGLDPFLAYQMGSLNAAECFGLKTKGAV
APGYDADLLFISDFENVSITKTMINGVIWSGTEQSQSTGGKAASGLLQSVHLSDLHENDLQIPIVQENEIRVIDIIPNQL
ETKLSLAKPKSGAFFQPDLESDLLKIAVVERHRGVKEIGLGVVRGFGLKEGAIATTISHDSHNLIAVGTNDQDILKAIER
LGEIGGGLTIAKGGKELQSVALPIAGLLSDKPLETVNESLKSLHAAITETGFSGAFNPFLTLSFLALPVIPDIKMTTEGL
FDVKAFRHIPVQP

Sequences:

>Translated_573_residues
MDKEMFIRRLGAASHRKKAETVIKNGKIMDVFNQEWLETDIAITDGAIVGLGEYEGGNIIDAEGQMIVPGFIDGHVHIES
SMVTPPEFAKAVIPHGVTTVVTDPHEIANVSGVKGLEFMLEQAEMTRLNIYFMLPSCVPAAPFEKSGAILNAADLHPFYS
REEVLGLAEVMDYVAVEAGEPDMVQKLIDADKAGKRIDGHLAGLSAGFVNVYRAAGVLTDHEVTTPEEALERVRRGMYVM
LREGSAAKNTRHVLPAVNEKNVRRFFFCTDDKHLDELVDEGSINYQVKLAIQEGLDPFLAYQMGSLNAAECFGLKTKGAV
APGYDADLLFISDFENVSITKTMINGVIWSGTEQSQSTGGKAASGLLQSVHLSDLHENDLQIPIVQENEIRVIDIIPNQL
ETKLSLAKPKSGAFFQPDLESDLLKIAVVERHRGVKEIGLGVVRGFGLKEGAIATTISHDSHNLIAVGTNDQDILKAIER
LGEIGGGLTIAKGGKELQSVALPIAGLLSDKPLETVNESLKSLHAAITETGFSGAFNPFLTLSFLALPVIPDIKMTTEGL
FDVKAFRHIPVQP
>Mature_573_residues
MDKEMFIRRLGAASHRKKAETVIKNGKIMDVFNQEWLETDIAITDGAIVGLGEYEGGNIIDAEGQMIVPGFIDGHVHIES
SMVTPPEFAKAVIPHGVTTVVTDPHEIANVSGVKGLEFMLEQAEMTRLNIYFMLPSCVPAAPFEKSGAILNAADLHPFYS
REEVLGLAEVMDYVAVEAGEPDMVQKLIDADKAGKRIDGHLAGLSAGFVNVYRAAGVLTDHEVTTPEEALERVRRGMYVM
LREGSAAKNTRHVLPAVNEKNVRRFFFCTDDKHLDELVDEGSINYQVKLAIQEGLDPFLAYQMGSLNAAECFGLKTKGAV
APGYDADLLFISDFENVSITKTMINGVIWSGTEQSQSTGGKAASGLLQSVHLSDLHENDLQIPIVQENEIRVIDIIPNQL
ETKLSLAKPKSGAFFQPDLESDLLKIAVVERHRGVKEIGLGVVRGFGLKEGAIATTISHDSHNLIAVGTNDQDILKAIER
LGEIGGGLTIAKGGKELQSVALPIAGLLSDKPLETVNESLKSLHAAITETGFSGAFNPFLTLSFLALPVIPDIKMTTEGL
FDVKAFRHIPVQP

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=557, Percent_Identity=36.4452423698384, Blast_Score=324, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_BACLD (Q65K51)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078843.1
- RefSeq:   YP_091256.1
- ProteinModelPortal:   Q65K51
- STRING:   Q65K51
- EnsemblBacteria:   EBBACT00000056233
- EnsemblBacteria:   EBBACT00000061047
- GeneID:   3030790
- GeneID:   3099912
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01667
- KEGG:   bli:BL01613
- NMPDR:   fig|279010.5.peg.1430
- eggNOG:   COG1001
- GeneTree:   EBGT00070000032083
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- ProtClustDB:   CLSK887242
- BioCyc:   BLIC279010-1:BLI01667-MONOMER
- BioCyc:   BLIC279010:BL01613-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 62083; Mature: 62083

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEMFIRRLGAASHRKKAETVIKNGKIMDVFNQEWLETDIAITDGAIVGLGEYEGGNII
CCHHHHHHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHHCCEEEECCEEEEECCCCCCCEE
DAEGQMIVPGFIDGHVHIESSMVTPPEFAKAVIPHGVTTVVTDPHEIANVSGVKGLEFML
CCCCCEEECEEECCEEEEECCCCCCHHHHHHHCCCCCEEEEECCHHHHCCCCCCHHHHHH
EQAEMTRLNIYFMLPSCVPAAPFEKSGAILNAADLHPFYSREEVLGLAEVMDYVAVEAGE
HHHHCEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCC
PDMVQKLIDADKAGKRIDGHLAGLSAGFVNVYRAAGVLTDHEVTTPEEALERVRRGMYVM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEE
LREGSAAKNTRHVLPAVNEKNVRRFFFCTDDKHLDELVDEGSINYQVKLAIQEGLDPFLA
EECCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEEHHCCCHHHH
YQMGSLNAAECFGLKTKGAVAPGYDADLLFISDFENVSITKTMINGVIWSGTEQSQSTGG
HHCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHCCEEECCCCCCCCCCC
KAASGLLQSVHLSDLHENDLQIPIVQENEIRVIDIIPNQLETKLSLAKPKSGAFFQPDLE
HHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHCCCCCCCEECCCCH
SDLLKIAVVERHRGVKEIGLGVVRGFGLKEGAIATTISHDSHNLIAVGTNDQDILKAIER
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHH
LGEIGGGLTIAKGGKELQSVALPIAGLLSDKPLETVNESLKSLHAAITETGFSGAFNPFL
HHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TLSFLALPVIPDIKMTTEGLFDVKAFRHIPVQP
HHHHHHHHCCCCCEECCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MDKEMFIRRLGAASHRKKAETVIKNGKIMDVFNQEWLETDIAITDGAIVGLGEYEGGNII
CCHHHHHHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHHCCEEEECCEEEEECCCCCCCEE
DAEGQMIVPGFIDGHVHIESSMVTPPEFAKAVIPHGVTTVVTDPHEIANVSGVKGLEFML
CCCCCEEECEEECCEEEEECCCCCCHHHHHHHCCCCCEEEEECCHHHHCCCCCCHHHHHH
EQAEMTRLNIYFMLPSCVPAAPFEKSGAILNAADLHPFYSREEVLGLAEVMDYVAVEAGE
HHHHCEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCC
PDMVQKLIDADKAGKRIDGHLAGLSAGFVNVYRAAGVLTDHEVTTPEEALERVRRGMYVM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEE
LREGSAAKNTRHVLPAVNEKNVRRFFFCTDDKHLDELVDEGSINYQVKLAIQEGLDPFLA
EECCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEEHHCCCHHHH
YQMGSLNAAECFGLKTKGAVAPGYDADLLFISDFENVSITKTMINGVIWSGTEQSQSTGG
HHCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHCCEEECCCCCCCCCCC
KAASGLLQSVHLSDLHENDLQIPIVQENEIRVIDIIPNQLETKLSLAKPKSGAFFQPDLE
HHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHCCCCCCCEECCCCH
SDLLKIAVVERHRGVKEIGLGVVRGFGLKEGAIATTISHDSHNLIAVGTNDQDILKAIER
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHH
LGEIGGGLTIAKGGKELQSVALPIAGLLSDKPLETVNESLKSLHAAITETGFSGAFNPFL
HHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TLSFLALPVIPDIKMTTEGLFDVKAFRHIPVQP
HHHHHHHHCCCCCEECCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA