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The map label for this gene is fruR [H]

Identifier: 52785413

GI number: 52785413

Start: 1612939

End: 1613694

Strand: Direct

Name: fruR [H]

Synonym: BLi01652

Alternate gene names: 52785413

Gene position: 1612939-1613694 (Clockwise)

Preceding gene: 52785412

Following gene: 52785414

Centisome position: 38.2

GC content: 42.59

Gene sequence:

>756_bases
GTGTTGACTCCCGAACGGCATCAGCTGATTATTGACGAGATTGAAAAGCATGATGTCGTGAAAATCCAGTACTTAATGAA
TTTAACGAACGCATCTGAGTCAACGATCAGAAGAGATTTGTCGACGCTGGAAGCCCGCGGATATTTAAAGCGTGTTCATG
GAGGGGCATCAAGGCTTTCCGATATTCGTACGGAGCCTGACATGCTAGAGAAATCATCCAAAAACCTTCATGAAAAGCGA
AAAATCGCTCAAGAAGCGGCCTCACTTCTTGAAGAAGGCGATTGTATTTACCTTGATGCCGGAACGACCACATTGCAAAT
GATCGATTTTATCAATCCAGAGATGGATATTATCGTGGTTACAAATGGAGTCATGCACATTGAGGCACTAGGTAAAAAAG
GCATTACTTTTTATTTATTAGGCGGGTATGTGAAGTATAAAACCGGAGCGATCGTAGGCGGTTCGGCTTTATCAGCCATC
AGCCAATACCGGTTTGACAAAAGCTTCATCGGCGTCAACGGCATTCATAAGGAAGCGGGGTTCACGACTCCGGATCCTGA
AGAAGCGCTTTTGAAAACAAAAGCTGTCAACCAGGCGAAAAAAGCATTTATTTTAGCTGACGTTTCCAAGTTTGGGGAAA
TTTCATTTTCTGCCTTTGCCGGTTTAGACGAAGCAACTATCATTACAGCAGGATCTGCAAAACATTCATTTGATAACTAT
CAAGAAAAAACTGTCGTAAAGGTAGTGAAAACATGA

Upstream 100 bases:

>100_bases
TTATTGAATGAATTTGAAAGATTTTTGTTGAGTTATGTCGAAAAAGCGTTTACAATGAAATTGTAAGCTTAATGAAGGCG
TTTCCAAAAGGGGTGATAAT

Downstream 100 bases:

>100_bases
TATACACTGTAACTCTCAACCCATCGGTCGACTATATTGTTCACGTTGAAGAATTTTCTGTAGGCGGGCTGAATCGTTCA
GTCTATGACACGAAATATCC

Product: FruR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTPERHQLIIDEIEKHDVVKIQYLMNLTNASESTIRRDLSTLEARGYLKRVHGGASRLSDIRTEPDMLEKSSKNLHEKR
KIAQEAASLLEEGDCIYLDAGTTTLQMIDFINPEMDIIVVTNGVMHIEALGKKGITFYLLGGYVKYKTGAIVGGSALSAI
SQYRFDKSFIGVNGIHKEAGFTTPDPEEALLKTKAVNQAKKAFILADVSKFGEISFSAFAGLDEATIITAGSAKHSFDNY
QEKTVVKVVKT

Sequences:

>Translated_251_residues
MLTPERHQLIIDEIEKHDVVKIQYLMNLTNASESTIRRDLSTLEARGYLKRVHGGASRLSDIRTEPDMLEKSSKNLHEKR
KIAQEAASLLEEGDCIYLDAGTTTLQMIDFINPEMDIIVVTNGVMHIEALGKKGITFYLLGGYVKYKTGAIVGGSALSAI
SQYRFDKSFIGVNGIHKEAGFTTPDPEEALLKTKAVNQAKKAFILADVSKFGEISFSAFAGLDEATIITAGSAKHSFDNY
QEKTVVKVVKT
>Mature_251_residues
MLTPERHQLIIDEIEKHDVVKIQYLMNLTNASESTIRRDLSTLEARGYLKRVHGGASRLSDIRTEPDMLEKSSKNLHEKR
KIAQEAASLLEEGDCIYLDAGTTTLQMIDFINPEMDIIVVTNGVMHIEALGKKGITFYLLGGYVKYKTGAIVGGSALSAI
SQYRFDKSFIGVNGIHKEAGFTTPDPEEALLKTKAVNQAKKAFILADVSKFGEISFSAFAGLDEATIITAGSAKHSFDNY
QEKTVVKVVKT

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=218, Percent_Identity=32.5688073394495, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=31.4741035856574, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=30.5555555555556, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787540, Length=216, Percent_Identity=32.8703703703704, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789829, Length=213, Percent_Identity=28.6384976525822, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=29.6943231441048, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790753, Length=233, Percent_Identity=24.4635193133047, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788069, Length=221, Percent_Identity=25.3393665158371, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI87082344, Length=208, Percent_Identity=25.9615384615385, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787063, Length=237, Percent_Identity=27.0042194092827, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27645; Mature: 27645

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPERHQLIIDEIEKHDVVKIQYLMNLTNASESTIRRDLSTLEARGYLKRVHGGASRLS
CCCCHHHHHHHHHHCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DIRTEPDMLEKSSKNLHEKRKIAQEAASLLEEGDCIYLDAGTTTLQMIDFINPEMDIIVV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEEE
TNGVMHIEALGKKGITFYLLGGYVKYKTGAIVGGSALSAISQYRFDKSFIGVNGIHKEAG
ECCEEEEEECCCCCCEEEEECCEEEEECCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCC
FTTPDPEEALLKTKAVNQAKKAFILADVSKFGEISFSAFAGLDEATIITAGSAKHSFDNY
CCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCHHHHCCCCCCEEEEECCCCCCHHHH
QEKTVVKVVKT
HHHHHEEEECC
>Mature Secondary Structure
MLTPERHQLIIDEIEKHDVVKIQYLMNLTNASESTIRRDLSTLEARGYLKRVHGGASRLS
CCCCHHHHHHHHHHCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DIRTEPDMLEKSSKNLHEKRKIAQEAASLLEEGDCIYLDAGTTTLQMIDFINPEMDIIVV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEEE
TNGVMHIEALGKKGITFYLLGGYVKYKTGAIVGGSALSAISQYRFDKSFIGVNGIHKEAG
ECCEEEEEECCCCCCEEEEECCEEEEECCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCC
FTTPDPEEALLKTKAVNQAKKAFILADVSKFGEISFSAFAGLDEATIITAGSAKHSFDNY
CCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCHHHHCCCCCCEEEEECCCCCCHHHH
QEKTVVKVVKT
HHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]