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The map label for this gene is moaE [H]

Identifier: 52785404

GI number: 52785404

Start: 1603504

End: 1603998

Strand: Direct

Name: moaE [H]

Synonym: BLi01643

Alternate gene names: 52785404

Gene position: 1603504-1603998 (Clockwise)

Preceding gene: 52785403

Following gene: 52785405

Centisome position: 37.97

GC content: 49.49

Gene sequence:

>495_bases
TTGTCTGAACGATTTATCATAACAAAAGACCCGATTGTCATCGAAGATGTCGTCAAAAAAGTTGAAAGAAGGGAAGCCGG
TGCCGTCACGACGTTTATCGGAACAGTGAGAGAATGGACCAACGGAAAAAAGACCCTCTATCTCGAATATGAAGCTTATG
TTCCAATGGCGGTCAGCATGCTCGCTCAGATCGGCAAAGAAATCAATGAAAAATGGCCCGGCACAGCTGCAGCCATTACC
CATCGCATCGGCAGGCTGGACATTTCTGACGCGGCCGTTGTCATCGCCGTGTCGTCGCCTCACCGGAAAGCGGCGTATGA
AGCGAATGAATATGCTATCGAAAGAATAAAGCAAATCGTCCCGATTTGGAAAAAAGAACATTGGGAGGACGGCGAGACTT
GGATCGGCGACCAGCTTGAGACAACTGAATACCCGGAAGGGAAACCGGATATTGAAGAGGCGGCTTCCGGCAGAGAAAGA
GGTGCTGACCATTGA

Upstream 100 bases:

>100_bases
TTTACCAGCAGAGCGAGCCGAAAACAGATGTTCCATCCTTTCATATTGAAGACCCGGGTGCCCTGGCTTTTATTCTGAAT
CATCTAAAGGAGGAAGGCGT

Downstream 100 bases:

>100_bases
TTAAAATTTTGCTGTTTGCCCAGCTTGCGGAACAAGCGGGTGCGCAGAGTATCGATATAGATGAAGAAAAGACGACAACA
GACGAGATTAGACAGTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSERFIITKDPIVIEDVVKKVERREAGAVTTFIGTVREWTNGKKTLYLEYEAYVPMAVSMLAQIGKEINEKWPGTAAAIT
HRIGRLDISDAAVVIAVSSPHRKAAYEANEYAIERIKQIVPIWKKEHWEDGETWIGDQLETTEYPEGKPDIEEAASGRER
GADH

Sequences:

>Translated_164_residues
MSERFIITKDPIVIEDVVKKVERREAGAVTTFIGTVREWTNGKKTLYLEYEAYVPMAVSMLAQIGKEINEKWPGTAAAIT
HRIGRLDISDAAVVIAVSSPHRKAAYEANEYAIERIKQIVPIWKKEHWEDGETWIGDQLETTEYPEGKPDIEEAASGRER
GADH
>Mature_163_residues
SERFIITKDPIVIEDVVKKVERREAGAVTTFIGTVREWTNGKKTLYLEYEAYVPMAVSMLAQIGKEINEKWPGTAAAITH
RIGRLDISDAAVVIAVSSPHRKAAYEANEYAIERIKQIVPIWKKEHWEDGETWIGDQLETTEYPEGKPDIEEAASGRERG
ADH

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=132, Percent_Identity=43.1818181818182, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI1787003, Length=114, Percent_Identity=37.719298245614, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=133, Percent_Identity=34.5864661654135, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356259, Length=128, Percent_Identity=40.625, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18524; Mature: 18393

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERFIITKDPIVIEDVVKKVERREAGAVTTFIGTVREWTNGKKTLYLEYEAYVPMAVSM
CCCCEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHH
LAQIGKEINEKWPGTAAAITHRIGRLDISDAAVVIAVSSPHRKAAYEANEYAIERIKQIV
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
PIWKKEHWEDGETWIGDQLETTEYPEGKPDIEEAASGRERGADH
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHCCCCC
>Mature Secondary Structure 
SERFIITKDPIVIEDVVKKVERREAGAVTTFIGTVREWTNGKKTLYLEYEAYVPMAVSM
CCCEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHH
LAQIGKEINEKWPGTAAAITHRIGRLDISDAAVVIAVSSPHRKAAYEANEYAIERIKQIV
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
PIWKKEHWEDGETWIGDQLETTEYPEGKPDIEEAASGRERGADH
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]