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The map label for this gene is ykvY [H]

Identifier: 52785357

GI number: 52785357

Start: 1557095

End: 1558189

Strand: Direct

Name: ykvY [H]

Synonym: BLi01594

Alternate gene names: 52785357

Gene position: 1557095-1558189 (Clockwise)

Preceding gene: 52785356

Following gene: 52785358

Centisome position: 36.87

GC content: 48.22

Gene sequence:

>1095_bases
ATGGAAAGAATTGAACAAATCTCTTCCTGGCTGAAAGAAAAAAACATATCTTCGGCTTTTATTCATTCAAAAGAAAACGT
ATTTTATCTTACCGGCTTTTATACAGAACCGCATGAACGGCTGATGGGCGTTTTTATTTTTCAAGATGAAGAGCCGTTTT
TTGTTTGTCCGCAAATGGAGGCCGGTCAGGCGAGAGCAGCCGGCTGGGCGTATGAGATCATCGGATACGGGGATCATCAA
AACCCTTGGGAACTCATATCCTCAGCGCTTCAAAAGCGAAACGGCCAATGTTTAAAAGTGGCGGTTGAAAAAGAAACGCT
TGCTCTTTCGCGCGCCGAAATGCTGCAGGCGGTCACAAACGGTGCGGAGCTTGTCTCTGCAGAAGAAAGGCTGAACCAAA
TCCGCGTCATCAAAGACGAAAAAGAAATCAGCATCCTCCGCGAAGCGGCCAAGCTTGCCGATTACGGGGTCGAAGCAGGA
GCCGCCGCATTAAAAGAGGGGATAGCGGAAATCGATGTCGTCGCTAAAATCGAGTATGAGCTGAAGAAAAAAGGAGTCCA
GGGGATGTCGTTTTCCACAATGGTCCTTTTTGGAGAAAAATCGGGACAGCCGCACGGAAACCCCGGCAGCCGGACGCTCA
AGCCGGGCGATTTCGTCCTCTTTGATTTAGGTGTAATCATTGACGGATACTGCTCTGATATTACAAGGACGCTCGTGTAT
CAAAATGTGAGCGAAAAACAAAAAGAAATATATAATACGGTGCTTCAAGCCGAAACGGAGGCGCTTAAGATGAGCAAACC
CGGTGTGAGAATCGGCGATCTTGATTTAAAAGCGCGCGGCATCATCGAAAAAGCGGGCTACGGCGATTACTTTCCGCACC
GCCTAGGGCACGGGCTCGGGATTTCGCCTCATGAATACCCGTCCATGAGCCATAACAATGACGAACTTTTGAAACAAGGC
ATGGTATACACGATTGAACCCGGCATCTATGTGCCGGAAATCGGAGGCGTTCGCATCGAGGATGATGTACTTGTTACAGC
CGATGGAGCAGAAGCGCTGACAAAGTATCCAAAAGAGCTGACTGTCATTTCATAA

Upstream 100 bases:

>100_bases
TAAGCGGTGAGCAAGAGACGGGAAAAACTGATACAATGGATATGATGCTTTTACATTTTACATGTATGGTACGGAAACTG
TCTCAAGGAGTGAACAGAGC

Downstream 100 bases:

>100_bases
AAAATGGAACCCGCCGTGCGCGGGTTCTATTTTATTACGGAAGTGAATCTTTTCATCTCACCGTCAATCCTTTGAAATGA
AGAAATCGTCAAAGGAACGG

Product: YkvY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MERIEQISSWLKEKNISSAFIHSKENVFYLTGFYTEPHERLMGVFIFQDEEPFFVCPQMEAGQARAAGWAYEIIGYGDHQ
NPWELISSALQKRNGQCLKVAVEKETLALSRAEMLQAVTNGAELVSAEERLNQIRVIKDEKEISILREAAKLADYGVEAG
AAALKEGIAEIDVVAKIEYELKKKGVQGMSFSTMVLFGEKSGQPHGNPGSRTLKPGDFVLFDLGVIIDGYCSDITRTLVY
QNVSEKQKEIYNTVLQAETEALKMSKPGVRIGDLDLKARGIIEKAGYGDYFPHRLGHGLGISPHEYPSMSHNNDELLKQG
MVYTIEPGIYVPEIGGVRIEDDVLVTADGAEALTKYPKELTVIS

Sequences:

>Translated_364_residues
MERIEQISSWLKEKNISSAFIHSKENVFYLTGFYTEPHERLMGVFIFQDEEPFFVCPQMEAGQARAAGWAYEIIGYGDHQ
NPWELISSALQKRNGQCLKVAVEKETLALSRAEMLQAVTNGAELVSAEERLNQIRVIKDEKEISILREAAKLADYGVEAG
AAALKEGIAEIDVVAKIEYELKKKGVQGMSFSTMVLFGEKSGQPHGNPGSRTLKPGDFVLFDLGVIIDGYCSDITRTLVY
QNVSEKQKEIYNTVLQAETEALKMSKPGVRIGDLDLKARGIIEKAGYGDYFPHRLGHGLGISPHEYPSMSHNNDELLKQG
MVYTIEPGIYVPEIGGVRIEDDVLVTADGAEALTKYPKELTVIS
>Mature_364_residues
MERIEQISSWLKEKNISSAFIHSKENVFYLTGFYTEPHERLMGVFIFQDEEPFFVCPQMEAGQARAAGWAYEIIGYGDHQ
NPWELISSALQKRNGQCLKVAVEKETLALSRAEMLQAVTNGAELVSAEERLNQIRVIKDEKEISILREAAKLADYGVEAG
AAALKEGIAEIDVVAKIEYELKKKGVQGMSFSTMVLFGEKSGQPHGNPGSRTLKPGDFVLFDLGVIIDGYCSDITRTLVY
QNVSEKQKEIYNTVLQAETEALKMSKPGVRIGDLDLKARGIIEKAGYGDYFPHRLGHGLGISPHEYPSMSHNNDELLKQG
MVYTIEPGIYVPEIGGVRIEDDVLVTADGAEALTKYPKELTVIS

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=265, Percent_Identity=31.6981132075472, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI149589008, Length=291, Percent_Identity=29.8969072164948, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI260593665, Length=291, Percent_Identity=29.8969072164948, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI260593663, Length=245, Percent_Identity=30.6122448979592, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=27.4193548387097, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI93141226, Length=237, Percent_Identity=29.957805907173, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI264681563, Length=191, Percent_Identity=31.9371727748691, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788728, Length=371, Percent_Identity=33.4231805929919, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1789275, Length=280, Percent_Identity=28.9285714285714, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790282, Length=292, Percent_Identity=25, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786364, Length=205, Percent_Identity=26.8292682926829, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71989583, Length=249, Percent_Identity=26.9076305220884, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=28.9752650176678, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320922, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323273, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920384, Length=324, Percent_Identity=28.0864197530864, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21357079, Length=294, Percent_Identity=28.9115646258503, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355531, Length=239, Percent_Identity=28.4518828451883, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40397; Mature: 40397

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIEQISSWLKEKNISSAFIHSKENVFYLTGFYTEPHERLMGVFIFQDEEPFFVCPQME
CCHHHHHHHHHHHCCCCHHEEECCCCEEEEEEECCCHHHHEEEEEEEECCCCEEECCCCC
AGQARAAGWAYEIIGYGDHQNPWELISSALQKRNGQCLKVAVEKETLALSRAEMLQAVTN
CCCCHHCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHC
GAELVSAEERLNQIRVIKDEKEISILREAAKLADYGVEAGAAALKEGIAEIDVVAKIEYE
CHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHEEHEEEEHHH
LKKKGVQGMSFSTMVLFGEKSGQPHGNPGSRTLKPGDFVLFDLGVIIDGYCSDITRTLVY
HHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
QNVSEKQKEIYNTVLQAETEALKMSKPGVRIGDLDLKARGIIEKAGYGDYFPHRLGHGLG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHCCCCCCCHHHHCCCCC
ISPHEYPSMSHNNDELLKQGMVYTIEPGIYVPEIGGVRIEDDVLVTADGAEALTKYPKEL
CCCCCCCCCCCCCHHHHHCCCEEEECCCEEECCCCCEEEECCEEEEECCHHHHHHCCCCE
TVIS
EECC
>Mature Secondary Structure
MERIEQISSWLKEKNISSAFIHSKENVFYLTGFYTEPHERLMGVFIFQDEEPFFVCPQME
CCHHHHHHHHHHHCCCCHHEEECCCCEEEEEEECCCHHHHEEEEEEEECCCCEEECCCCC
AGQARAAGWAYEIIGYGDHQNPWELISSALQKRNGQCLKVAVEKETLALSRAEMLQAVTN
CCCCHHCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHC
GAELVSAEERLNQIRVIKDEKEISILREAAKLADYGVEAGAAALKEGIAEIDVVAKIEYE
CHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHEEHEEEEHHH
LKKKGVQGMSFSTMVLFGEKSGQPHGNPGSRTLKPGDFVLFDLGVIIDGYCSDITRTLVY
HHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
QNVSEKQKEIYNTVLQAETEALKMSKPGVRIGDLDLKARGIIEKAGYGDYFPHRLGHGLG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHCCCCCCCHHHHCCCCC
ISPHEYPSMSHNNDELLKQGMVYTIEPGIYVPEIGGVRIEDDVLVTADGAEALTKYPKEL
CCCCCCCCCCCCCHHHHHCCCEEEECCCEEECCCCCEEEECCEEEEECCHHHHHHCCCCE
TVIS
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]