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The map label for this gene is pfbA [H]

Identifier: 52785326

GI number: 52785326

Start: 1532567

End: 1534546

Strand: Direct

Name: pfbA [H]

Synonym: BLi01562

Alternate gene names: 52785326

Gene position: 1532567-1534546 (Clockwise)

Preceding gene: 52785325

Following gene: 52785327

Centisome position: 36.29

GC content: 45.51

Gene sequence:

>1980_bases
TTGGGAAAGTTCTATTATAAAAAAGCCACAACAAGCGGGTTTGATCGCCAATATATAAAAGACCAAAATCAAAACCTAGA
TGACATAGGTAAGGACATCCGAGAAGTTGACACAAAAATAAATGATCATAAAAAAGCCAAAAACGCCCATACATCCGAAC
AAATATCGCACGAAAGCGGACTAAATGTCGGACAGGAAATCGAAGTAACGAAGGCGCGCTTTAGAAATCTCGTCCTAAAT
GTCGACGGAACCAACGTTAAAGAAGTCGTCGATGCCCGTGTCGGCCGGGACGGGACGATTTATCCGACGCTCAGGGATCG
TTTAGACGCCGACGGACAGACGGTTGATGACATAAAGGACGATCTTATCACGAGAATCAGCTTTAAAAATGCACTTAGTT
ATGGCGCAGATCCTACGGGGAAAACACCGTCAGCGGATGCGATTCAAAGCGCGCTGGACGAAATCCACAGCGAAGGTGGT
GGTTGGCTCGTCATTCCTGGCGGTACTTATCTGATCGATAAACGCATGATCATTTACGAAAACACACGCGTTACAATGGC
GGCTGATTGCGTGCTGCTTCGAGGATGGTCTGGCGGATTCTTTGCAAACGGTAAGCCCACCGATAATTTCTCCGGATATT
CCGGAAGAGGTAACATCGTCATTGAGGGCGGTATGTTAGATGGGAATTACCTGAAGATCGAAACATATAAAACGAATGCG
ATGGACAGCGTTATTATCGGTCACGCGAAAAATATCGTTATCGATAACGTAACGTTTAAAGACGTAATTACCGACCACGC
AATCGATGCGAACGGATGTAACGGCCTTCGAATCACAAATTGCAGATTTACCGGATTTATCGATACTAGCGGAACACGTC
CTTTTTCTGAAGCGATTCAGCTCGGAGAGTTTACGAAAGGCGGCGTCAACATTTTCGGTGCCTTCGACAGCACGCCGAAC
ACTAACGTCTATATTGCGCATAACTACTTCGGAAAGTCCGATCTTTTAGGCGGTTGGGGATGCGCTGTCGGAAACCACTA
CGCTGTATACGACGTGTTCCAGACGAACATAACGATATTCGACAATACGATTGAGGATTGCGGGTTTGCTGGCATTCGTA
CATTTAAATGGGGCGAAGTTAAAATTATTAACAACGTCTTCAGACGGAATCGGGAGTGCGTCCGGATTTCGCAAGTTTCC
GGCGGAATCGAGAGCTCTAAAAATGCCTCTGGCGTACAGATGAATCGCCCACAAAACGCTCAAAACATTCTAATCCAAGG
GAATGACTTCTACGAGTATACGGTCTGCGGAGTAGTTACCTACGGGCAGATTTACAATAAGGAAGCTGCTTGGAGCGATG
GTATCCGGATCTTCGGAAACTACTTTAAACTGCGGGAGAAAGATATCGGCAGCTACGGCAATGAGCAGGCGATTCAGATA
ATCTACGGAAGGAACGTCTTCATCTCCGATAACAGGATTTTCGGAGGGCGTAGGGGCATCTGGCTCGAGGGTTGTTTTAA
TACGTTCATCTCGAACAATTATATATCATGTGTAGATACGGAAGCAGTTTACGTTGCGAAAAGCCGCGATACATCTTCGA
CTATCACAAAATCTACACATTTATCGATAGACGGGAACGAAATTAACACGATCGGGCGAAACGGGATCTACGTCCAGAAC
TGCGATAATTTTGATGTGCGGAACAACAACATATTCAATACGAATATCGAACAAGGATCAAAAGATCGCGGAGGTGTTTT
CGTAGAAAAGGCTTACGATGGACGTATCGAAGGTAACCGAATCCGAGGTGTAGAGAAAATATTCGCCATCTTAGTCCAGT
CTACCGCAACTGAAGTGAACGTGTTTAACACGAAGGGAACTGGTCGCGTCATCGTTCAAGGTGATTCGAATCTTAACGGG
TATTACGGCACAACACAGAATGATTATATAAGAAAAATCAGCACGAAGAGCAGCAGCTAA

Upstream 100 bases:

>100_bases
TGTTTGCATTGAGAATATCTCAAACAAAGATACTCCCAATCAGTTTATCGGTATCTATACGCAATTTAAAGCGATTTAAA
AATAGCGGAGGTGATAACGC

Downstream 100 bases:

>100_bases
ATTAAAGGGAGGGATGTCTCCGTATGATATATAAAGATTCCGAAGTCCATTTCAATATAAGCTCGCAAATTAAACGAAGT
GTTTCCGCGAACATTCAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MGKFYYKKATTSGFDRQYIKDQNQNLDDIGKDIREVDTKINDHKKAKNAHTSEQISHESGLNVGQEIEVTKARFRNLVLN
VDGTNVKEVVDARVGRDGTIYPTLRDRLDADGQTVDDIKDDLITRISFKNALSYGADPTGKTPSADAIQSALDEIHSEGG
GWLVIPGGTYLIDKRMIIYENTRVTMAADCVLLRGWSGGFFANGKPTDNFSGYSGRGNIVIEGGMLDGNYLKIETYKTNA
MDSVIIGHAKNIVIDNVTFKDVITDHAIDANGCNGLRITNCRFTGFIDTSGTRPFSEAIQLGEFTKGGVNIFGAFDSTPN
TNVYIAHNYFGKSDLLGGWGCAVGNHYAVYDVFQTNITIFDNTIEDCGFAGIRTFKWGEVKIINNVFRRNRECVRISQVS
GGIESSKNASGVQMNRPQNAQNILIQGNDFYEYTVCGVVTYGQIYNKEAAWSDGIRIFGNYFKLREKDIGSYGNEQAIQI
IYGRNVFISDNRIFGGRRGIWLEGCFNTFISNNYISCVDTEAVYVAKSRDTSSTITKSTHLSIDGNEINTIGRNGIYVQN
CDNFDVRNNNIFNTNIEQGSKDRGGVFVEKAYDGRIEGNRIRGVEKIFAILVQSTATEVNVFNTKGTGRVIVQGDSNLNG
YYGTTQNDYIRKISTKSSS

Sequences:

>Translated_659_residues
MGKFYYKKATTSGFDRQYIKDQNQNLDDIGKDIREVDTKINDHKKAKNAHTSEQISHESGLNVGQEIEVTKARFRNLVLN
VDGTNVKEVVDARVGRDGTIYPTLRDRLDADGQTVDDIKDDLITRISFKNALSYGADPTGKTPSADAIQSALDEIHSEGG
GWLVIPGGTYLIDKRMIIYENTRVTMAADCVLLRGWSGGFFANGKPTDNFSGYSGRGNIVIEGGMLDGNYLKIETYKTNA
MDSVIIGHAKNIVIDNVTFKDVITDHAIDANGCNGLRITNCRFTGFIDTSGTRPFSEAIQLGEFTKGGVNIFGAFDSTPN
TNVYIAHNYFGKSDLLGGWGCAVGNHYAVYDVFQTNITIFDNTIEDCGFAGIRTFKWGEVKIINNVFRRNRECVRISQVS
GGIESSKNASGVQMNRPQNAQNILIQGNDFYEYTVCGVVTYGQIYNKEAAWSDGIRIFGNYFKLREKDIGSYGNEQAIQI
IYGRNVFISDNRIFGGRRGIWLEGCFNTFISNNYISCVDTEAVYVAKSRDTSSTITKSTHLSIDGNEINTIGRNGIYVQN
CDNFDVRNNNIFNTNIEQGSKDRGGVFVEKAYDGRIEGNRIRGVEKIFAILVQSTATEVNVFNTKGTGRVIVQGDSNLNG
YYGTTQNDYIRKISTKSSS
>Mature_658_residues
GKFYYKKATTSGFDRQYIKDQNQNLDDIGKDIREVDTKINDHKKAKNAHTSEQISHESGLNVGQEIEVTKARFRNLVLNV
DGTNVKEVVDARVGRDGTIYPTLRDRLDADGQTVDDIKDDLITRISFKNALSYGADPTGKTPSADAIQSALDEIHSEGGG
WLVIPGGTYLIDKRMIIYENTRVTMAADCVLLRGWSGGFFANGKPTDNFSGYSGRGNIVIEGGMLDGNYLKIETYKTNAM
DSVIIGHAKNIVIDNVTFKDVITDHAIDANGCNGLRITNCRFTGFIDTSGTRPFSEAIQLGEFTKGGVNIFGAFDSTPNT
NVYIAHNYFGKSDLLGGWGCAVGNHYAVYDVFQTNITIFDNTIEDCGFAGIRTFKWGEVKIINNVFRRNRECVRISQVSG
GIESSKNASGVQMNRPQNAQNILIQGNDFYEYTVCGVVTYGQIYNKEAAWSDGIRIFGNYFKLREKDIGSYGNEQAIQII
YGRNVFISDNRIFGGRRGIWLEGCFNTFISNNYISCVDTEAVYVAKSRDTSSTITKSTHLSIDGNEINTIGRNGIYVQNC
DNFDVRNNNIFNTNIEQGSKDRGGVFVEKAYDGRIEGNRIRGVEKIFAILVQSTATEVNVFNTKGTGRVIVQGDSNLNGY
YGTTQNDYIRKISTKSSS

Specific function: Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 PbH1 repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050 [H]

Pfam domain/function: PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 72989; Mature: 72858

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFYYKKATTSGFDRQYIKDQNQNLDDIGKDIREVDTKINDHKKAKNAHTSEQISHESG
CCCEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
LNVGQEIEVTKARFRNLVLNVDGTNVKEVVDARVGRDGTIYPTLRDRLDADGQTVDDIKD
CCCCCEEHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCEECHHHHHHCCCCCCCHHHHHH
DLITRISFKNALSYGADPTGKTPSADAIQSALDEIHSEGGGWLVIPGGTYLIDKRMIIYE
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEECEEEEEE
NTRVTMAADCVLLRGWSGGFFANGKPTDNFSGYSGRGNIVIEGGMLDGNYLKIETYKTNA
CCEEEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECCEECCCEEEEEEEECCC
MDSVIIGHAKNIVIDNVTFKDVITDHAIDANGCNGLRITNCRFTGFIDTSGTRPFSEAIQ
CCEEEEECCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHH
LGEFTKGGVNIFGAFDSTPNTNVYIAHNYFGKSDLLGGWGCAVGNHYAVYDVFQTNITIF
HCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCEECCCCCCEEEEEEEECCEEEE
DNTIEDCGFAGIRTFKWGEVKIINNVFRRNRECVRISQVSGGIESSKNASGVQMNRPQNA
ECCHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEECCCCCC
QNILIQGNDFYEYTVCGVVTYGQIYNKEAAWSDGIRIFGNYFKLREKDIGSYGNEQAIQI
CEEEEECCCEEEEEEEEEEEECHHHCCCCCCCCCHHEEEHHHEEEHHHCCCCCCCCEEEE
IYGRNVFISDNRIFGGRRGIWLEGCFNTFISNNYISCVDTEAVYVAKSRDTSSTITKSTH
EECCEEEEECCEEECCCCCEEHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEEEEE
LSIDGNEINTIGRNGIYVQNCDNFDVRNNNIFNTNIEQGSKDRGGVFVEKAYDGRIEGNR
EEECCCEEEECCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCH
IRGVEKIFAILVQSTATEVNVFNTKGTGRVIVQGDSNLNGYYGTTQNDYIRKISTKSSS
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHEEECCCCCC
>Mature Secondary Structure 
GKFYYKKATTSGFDRQYIKDQNQNLDDIGKDIREVDTKINDHKKAKNAHTSEQISHESG
CCEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
LNVGQEIEVTKARFRNLVLNVDGTNVKEVVDARVGRDGTIYPTLRDRLDADGQTVDDIKD
CCCCCEEHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCEECHHHHHHCCCCCCCHHHHHH
DLITRISFKNALSYGADPTGKTPSADAIQSALDEIHSEGGGWLVIPGGTYLIDKRMIIYE
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEECEEEEEE
NTRVTMAADCVLLRGWSGGFFANGKPTDNFSGYSGRGNIVIEGGMLDGNYLKIETYKTNA
CCEEEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECCEECCCEEEEEEEECCC
MDSVIIGHAKNIVIDNVTFKDVITDHAIDANGCNGLRITNCRFTGFIDTSGTRPFSEAIQ
CCEEEEECCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHH
LGEFTKGGVNIFGAFDSTPNTNVYIAHNYFGKSDLLGGWGCAVGNHYAVYDVFQTNITIF
HCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCEECCCCCCEEEEEEEECCEEEE
DNTIEDCGFAGIRTFKWGEVKIINNVFRRNRECVRISQVSGGIESSKNASGVQMNRPQNA
ECCHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEECCCCCC
QNILIQGNDFYEYTVCGVVTYGQIYNKEAAWSDGIRIFGNYFKLREKDIGSYGNEQAIQI
CEEEEECCCEEEEEEEEEEEECHHHCCCCCCCCCHHEEEHHHEEEHHHCCCCCCCCEEEE
IYGRNVFISDNRIFGGRRGIWLEGCFNTFISNNYISCVDTEAVYVAKSRDTSSTITKSTH
EECCEEEEECCEEECCCCCEEHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEEEEE
LSIDGNEINTIGRNGIYVQNCDNFDVRNNNIFNTNIEQGSKDRGGVFVEKAYDGRIEGNR
EEECCCEEEECCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCH
IRGVEKIFAILVQSTATEVNVFNTKGTGRVIVQGDSNLNGYYGTTQNDYIRKISTKSSS
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11544234 [H]