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The map label for this gene is ykkD

Identifier: 52785178

GI number: 52785178

Start: 1406955

End: 1407269

Strand: Direct

Name: ykkD

Synonym: BLi01410

Alternate gene names: 52785178

Gene position: 1406955-1407269 (Clockwise)

Preceding gene: 52785177

Following gene: 52785179

Centisome position: 33.32

GC content: 52.06

Gene sequence:

>315_bases
ATGGAATGGATCTGCCTCATCGCCGCCGGTATACTGGAAATGCTTGGCGTGACGATGATGAACCAGTTTCATAAAGACAA
GCGGGTGAGATGGATCTTTTTGTTGATCATCGGGTTTGCCGCTTCTTTTTTCTTGCTTTCCCTTGCGATGGAGACGCTGC
CGATGGGAACCGCGTACGCAGTGTGGACAGGGATCGGCACGGTCGGAGGTGCGCTTGTCGGCATCCTGTTTTACGGAGAG
CCGAAAGACGGAAAACGCATCTTTTTCATCGCGCTCATTTTGGGATCTGCCGTCGGGCTGAAACTTATTAGCTAG

Upstream 100 bases:

>100_bases
AGCCGGCAAATATCGCCAAGCTTGCTCTGATCGGTGTTTTGCTATGCGGCGTGATCGGTTTGAAGCTTGTAACAAATGAA
GAGAAAGGGGAGGCGTCATA

Downstream 100 bases:

>100_bases
AGTCGGGTTGATGCAAATAGGCGTTCGTAAATTGATTTTTCAATAAACTCCAGTATAATGAAAAGATAGTTTACGAATTA
CAAGCAAAGAGGGTTTTTAC

Product: YkkD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MEWICLIAAGILEMLGVTMMNQFHKDKRVRWIFLLIIGFAASFFLLSLAMETLPMGTAYAVWTGIGTVGGALVGILFYGE
PKDGKRIFFIALILGSAVGLKLIS

Sequences:

>Translated_104_residues
MEWICLIAAGILEMLGVTMMNQFHKDKRVRWIFLLIIGFAASFFLLSLAMETLPMGTAYAVWTGIGTVGGALVGILFYGE
PKDGKRIFFIALILGSAVGLKLIS
>Mature_104_residues
MEWICLIAAGILEMLGVTMMNQFHKDKRVRWIFLLIIGFAASFFLLSLAMETLPMGTAYAVWTGIGTVGGALVGILFYGE
PKDGKRIFFIALILGSAVGLKLIS

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=42.156862745098, Blast_Score=77, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKKD_BACLD (Q65KV0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078599.2
- RefSeq:   YP_091007.1
- ProteinModelPortal:   Q65KV0
- STRING:   Q65KV0
- EnsemblBacteria:   EBBACT00000054260
- EnsemblBacteria:   EBBACT00000062652
- GeneID:   3030457
- GeneID:   3099361
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01410
- KEGG:   bli:BL03754
- NMPDR:   fig|279010.5.peg.865
- eggNOG:   COG2076
- GeneTree:   EBGT00050000001579
- HOGENOM:   HBG740972
- ProtClustDB:   CLSK887164
- BioCyc:   BLIC279010-1:BLI01410-MONOMER
- BioCyc:   BLIC279010:BL03754-MONOMER
- GO:   GO:0006810
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 11357; Mature: 11357

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xef18e90)-; HASH(0xf0e8234)-; HASH(0xcf2a1ec)-; HASH(0xedd02c8)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWICLIAAGILEMLGVTMMNQFHKDKRVRWIFLLIIGFAASFFLLSLAMETLPMGTAYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VWTGIGTVGGALVGILFYGEPKDGKRIFFIALILGSAVGLKLIS
HHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHEECH
>Mature Secondary Structure
MEWICLIAAGILEMLGVTMMNQFHKDKRVRWIFLLIIGFAASFFLLSLAMETLPMGTAYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VWTGIGTVGGALVGILFYGEPKDGKRIFFIALILGSAVGLKLIS
HHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA