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The map label for this gene is ykkC

Identifier: 52785177

GI number: 52785177

Start: 1406626

End: 1406955

Strand: Direct

Name: ykkC

Synonym: BLi01409

Alternate gene names: 52785177

Gene position: 1406626-1406955 (Clockwise)

Preceding gene: 52785176

Following gene: 52785178

Centisome position: 33.31

GC content: 53.94

Gene sequence:

>330_bases
ATGAGATGGGGCAGTGTCATACTTGCAGCCTTGTTTGAAATTGGCTGGGTCATGGGGCTGAAACACGCCGATTCGGCACT
TGAATGGATCTGCACGGCGGCCGCCGTCGTGATGAGCTTCTATATACTGGTGAAAGCGGGGGAGAAGCTGCCGGTCGGAA
CCGTGTATGCCGTATTTACCGGTCTCGGGACGGCGGGAACGGTCGTCTGCGAAATCGCCTTGTTCAATGAGCCGGCAAAT
ATCGCCAAGCTTGCTCTGATCGGTGTTTTGCTATGCGGCGTGATCGGTTTGAAGCTTGTAACAAATGAAGAGAAAGGGGA
GGCGTCATAA

Upstream 100 bases:

>100_bases
TTTGTTCATATGCACACGGAGGGATAAAAGCCCGGGAGTATCGTTTCCATCGATAGCCCGGGTTTTTTCTTTTGCTGAAA
ATGAAATTGGAGGGATTGTG

Downstream 100 bases:

>100_bases
TGGAATGGATCTGCCTCATCGCCGCCGGTATACTGGAAATGCTTGGCGTGACGATGATGAACCAGTTTCATAAAGACAAG
CGGGTGAGATGGATCTTTTT

Product: YkkC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MRWGSVILAALFEIGWVMGLKHADSALEWICTAAAVVMSFYILVKAGEKLPVGTVYAVFTGLGTAGTVVCEIALFNEPAN
IAKLALIGVLLCGVIGLKLVTNEEKGEAS

Sequences:

>Translated_109_residues
MRWGSVILAALFEIGWVMGLKHADSALEWICTAAAVVMSFYILVKAGEKLPVGTVYAVFTGLGTAGTVVCEIALFNEPAN
IAKLALIGVLLCGVIGLKLVTNEEKGEAS
>Mature_109_residues
MRWGSVILAALFEIGWVMGLKHADSALEWICTAAAVVMSFYILVKAGEKLPVGTVYAVFTGLGTAGTVVCEIALFNEPAN
IAKLALIGVLLCGVIGLKLVTNEEKGEAS

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=40.9523809523809, Blast_Score=70, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKKC_BACLD (Q65KV1)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078598.1
- RefSeq:   YP_091006.1
- ProteinModelPortal:   Q65KV1
- STRING:   Q65KV1
- EnsemblBacteria:   EBBACT00000054375
- EnsemblBacteria:   EBBACT00000059945
- GeneID:   3030456
- GeneID:   3100140
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01409
- KEGG:   bli:BL03755
- NMPDR:   fig|279010.5.peg.864
- eggNOG:   COG2076
- GeneTree:   EBGT00050000001579
- HOGENOM:   HBG740972
- OMA:   MQWLKVI
- ProtClustDB:   CLSK2523431
- BioCyc:   BLIC279010-1:BLI01409-MONOMER
- BioCyc:   BLIC279010:BL03755-MONOMER
- GO:   GO:0006810
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 11426; Mature: 11426

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xec56878)-; HASH(0xe17caf4)-; HASH(0xdd8633c)-; HASH(0xdf16ca0)-;

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWGSVILAALFEIGWVMGLKHADSALEWICTAAAVVMSFYILVKAGEKLPVGTVYAVFT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GLGTAGTVVCEIALFNEPANIAKLALIGVLLCGVIGLKLVTNEEKGEAS
CCCCCHHHHEEHEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
>Mature Secondary Structure
MRWGSVILAALFEIGWVMGLKHADSALEWICTAAAVVMSFYILVKAGEKLPVGTVYAVFT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GLGTAGTVVCEIALFNEPANIAKLALIGVLLCGVIGLKLVTNEEKGEAS
CCCCCHHHHEEHEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA