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The map label for this gene is ykhA [H]

Identifier: 52785170

GI number: 52785170

Start: 1401199

End: 1401720

Strand: Direct

Name: ykhA [H]

Synonym: BLi01402

Alternate gene names: 52785170

Gene position: 1401199-1401720 (Clockwise)

Preceding gene: 52785168

Following gene: 52785171

Centisome position: 33.18

GC content: 50.0

Gene sequence:

>522_bases
ATGATGAATGGACCTGAAAAGAGATACTGCAAAGAATCAAAAGTTGTCAAAACAAGCAGGGTATTTCCGCTTGATACGAA
CAATCACAACACCTTGTTCGGCGGCAAGCTGATGAGCTATATCGACGATATCGCTTCGATTTCGGCAGCGAGACACTCGA
GGTGTGAAACCGTGACAGCTTCAATGGATTCCGTCGATTTTCTCGAACCGATCCGCCAGGAGGATTCAGTCTGCCTTGAA
TCTTATGTGACATGGGTCGGCAGAACGTCAATGGAGGTATTCGTCAAAGTCATTAAAGAGCATTTGCTGACAGGCGAACG
AAAGCTTGCGGCGACATCCTTTTTAACCTTTGTGGCGCTTGATCAGGACGGCAATCCTCAGGCCGTTCCCCAAGTTGTAC
CGCAGTCTGAAGAAGAAATCATGCTGCACGAGACCGCCCGGCAGCGCGCCGAAGAACGGAAAAACCATCGCAAACACAGC
AAAGCGCTGGCCCAGGCGCTGGCTGTTGACAAACCTTGGTAA

Upstream 100 bases:

>100_bases
AGCCGGATAAAAAAGTTTAGACAAATGAATTCTAATAGTGTTTAATATAGAAAAAATCCACTTTACAAACGCATCTTAGT
AGACATCAAAGGAGTAATGG

Downstream 100 bases:

>100_bases
ACATACGAACAAAACCCCGGCTCAAGCATCAGTTTGCCGGGGTTTTGCTGTGCAATGAATACACTACCCAATATTTGTTC
AAAATAAATTACAAAAAACG

Product: YkhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MMNGPEKRYCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHSRCETVTASMDSVDFLEPIRQEDSVCLE
SYVTWVGRTSMEVFVKVIKEHLLTGERKLAATSFLTFVALDQDGNPQAVPQVVPQSEEEIMLHETARQRAEERKNHRKHS
KALAQALAVDKPW

Sequences:

>Translated_173_residues
MMNGPEKRYCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHSRCETVTASMDSVDFLEPIRQEDSVCLE
SYVTWVGRTSMEVFVKVIKEHLLTGERKLAATSFLTFVALDQDGNPQAVPQVVPQSEEEIMLHETARQRAEERKNHRKHS
KALAQALAVDKPW
>Mature_173_residues
MMNGPEKRYCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHSRCETVTASMDSVDFLEPIRQEDSVCLE
SYVTWVGRTSMEVFVKVIKEHLLTGERKLAATSFLTFVALDQDGNPQAVPQVVPQSEEEIMLHETARQRAEERKNHRKHS
KALAQALAVDKPW

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528282, Length=154, Percent_Identity=34.4155844155844, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI32528284, Length=154, Percent_Identity=34.4155844155844, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI75709208, Length=154, Percent_Identity=34.4155844155844, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI32528286, Length=154, Percent_Identity=34.4155844155844, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI22165355, Length=145, Percent_Identity=33.1034482758621, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI22165400, Length=145, Percent_Identity=33.1034482758621, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI18640736, Length=144, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787506, Length=123, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 19578; Mature: 19578

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNGPEKRYCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHSRCETVTA
CCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMDSVDFLEPIRQEDSVCLESYVTWVGRTSMEVFVKVIKEHLLTGERKLAATSFLTFVAL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEE
DQDGNPQAVPQVVPQSEEEIMLHETARQRAEERKNHRKHSKALAQALAVDKPW
CCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMNGPEKRYCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHSRCETVTA
CCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMDSVDFLEPIRQEDSVCLESYVTWVGRTSMEVFVKVIKEHLLTGERKLAATSFLTFVAL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEE
DQDGNPQAVPQVVPQSEEEIMLHETARQRAEERKNHRKHSKALAQALAVDKPW
CCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]