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The map label for this gene is dppE [H]

Identifier: 52785164

GI number: 52785164

Start: 1394367

End: 1395992

Strand: Direct

Name: dppE [H]

Synonym: BLi01396

Alternate gene names: 52785164

Gene position: 1394367-1395992 (Clockwise)

Preceding gene: 52785163

Following gene: 52785165

Centisome position: 33.02

GC content: 48.52

Gene sequence:

>1626_bases
ATGAAAAGGCTGACGAGCGTGTTGGCTTCCGCATTTGCGGTCATCCTGCTGTTCGGATGTACGGCAAATGAACAGGCGGG
GCAGGAAACGAAGAAGAAAGCGAAAGAAACGGCTGGAGAACAGGTTCTGAGGCTGAACAACGAAAATGAACCGACATCTT
TTGATCCGCCGATCGGCTTTAATAATGTCTCATGGCAGGCGCTGAACAATCTGATGGAAGGTTTGACAAGACTTGGCGCA
GACCATGAGCCCGAAGCGGCGTCCGCCGAAAAGTGGAACATTTCCGACGACGGGAAGACATATACTTTTACAATCCGTGA
TGATGCCAAATGGTCAAACGGAGACCCTTTAACCGCCGGGGATTTTGAATATGCGTGGAAGCGTCTGCTCGATCCGAAAA
CGGGCTCCTCTGCCGCGTTTTTAGGCTACTTTATCGAAGGCGGTGAGGCCTTTAACAGCGGAAAAGGTTCAAAAGATGAT
GTCAAAGTCAAAGCGGTGGATGAAAAGACGCTTAAGGTGACGCTTGAAAGTCCGCAGCAGTCGTTTTTAAGCATTGTAGC
CAATCCGGCCTTTTTCCCGGTTCCTCAGAAAATCGCCGAAGACAATCCGAAATGGCATGAAGAAGCAGCCACATTCGTCG
GCAACGGTCCGTTTAAGCTGGCAGAATGGAAGCACGATGAAAGCTTTACGATGGTAAAGAGCGATACGTATTGGGACCGG
GATACTGTGAAGCTTGATAAAGTGACATGGGCGATGGTCGATGACCGAAATACCGACTACCAAATGTTCGAGTCGAATGA
ACTTGATACGGCTTATGTCCCGGCTGAAATGAGCGAGAAGCTGATGGGCTCTGATGAGGTGAAGGTGTTTGATCAGGCGG
GTCTTTATTTTTACAGGTTCAATGTCAATAAAGAGCCGTTCCAGAATGAAAAAATCAGAAAAGCGTTTGCGATGGCCGTC
GATCAGCAGGAAATCGTCGATTACGTCACGAAAAACGGTGAAAAACCGGCACGCGGATTTGTGTCTCCGGGAATCAAAGG
GCCGAACGGCAAGGATTTTCGCGAGGAAGGCGGCGATTTGCTCAAATATAACGCCGATGAAGCGAAACAGCTGCTCGAAA
AAGGCATGAAGGAGGAAAACTACGAAAAGCTGCCCGCCGTTACCTTGACATACAGCACAAAACCGGAGCATAAAAAAATG
GCGGAAGCGGTTCAGCAAAAACTGAAAAGTACGCTCGGCGTCGATGTGAAGCTCGCCAATATGGAATGGAACACATTCCT
TGAAGAACAGAAGGCGCTCAAGTTCCAGTTTTCCCAAAGCTCTTTTCTGGCTGATTATGCGGATCCTATCAACTTCCTGG
AAAGCTTTCAAACGGGTAACGCAATGAACAGAACCGGCTGGGGCAATTCAGAGTATGACGAGCTGATCAAGGCGGCGAAA
AATGAAGCTGATGAAGAAAAGCGCACTGAGCTGCTGCATCAGGCTGAAGAACTGCTGTTTGAAGGGATGCCGATCATACC
GATCCACTTCTATAATCAAGTCCATTTGGAAAAGGAGAATGTGAAAGGCATCGTCCGTCATCCTGTCGGCTACATTGAAC
TGAAATGGGCCGAAAAAACGTCATGA

Upstream 100 bases:

>100_bases
GGCGGGTCATCGAGTGTGCTGCTGGCTTCAGGATGAAAGGGCAAAAAGGGCTCTGCTGACAACATAATCATAAAATCGAT
TTTTCAAATGGGGGGATTTG

Downstream 100 bases:

>100_bases
CCAAAATTGTCCGTCTGCTATTTTCTTTGTGCATACTGCCGCACAGGAGCGGACGGACTTTTCATAAAGGGGGATGTCTC
TGTTGAATATTGCGCCTCAA

Product: DppE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKRLTSVLASAFAVILLFGCTANEQAGQETKKKAKETAGEQVLRLNNENEPTSFDPPIGFNNVSWQALNNLMEGLTRLGA
DHEPEAASAEKWNISDDGKTYTFTIRDDAKWSNGDPLTAGDFEYAWKRLLDPKTGSSAAFLGYFIEGGEAFNSGKGSKDD
VKVKAVDEKTLKVTLESPQQSFLSIVANPAFFPVPQKIAEDNPKWHEEAATFVGNGPFKLAEWKHDESFTMVKSDTYWDR
DTVKLDKVTWAMVDDRNTDYQMFESNELDTAYVPAEMSEKLMGSDEVKVFDQAGLYFYRFNVNKEPFQNEKIRKAFAMAV
DQQEIVDYVTKNGEKPARGFVSPGIKGPNGKDFREEGGDLLKYNADEAKQLLEKGMKEENYEKLPAVTLTYSTKPEHKKM
AEAVQQKLKSTLGVDVKLANMEWNTFLEEQKALKFQFSQSSFLADYADPINFLESFQTGNAMNRTGWGNSEYDELIKAAK
NEADEEKRTELLHQAEELLFEGMPIIPIHFYNQVHLEKENVKGIVRHPVGYIELKWAEKTS

Sequences:

>Translated_541_residues
MKRLTSVLASAFAVILLFGCTANEQAGQETKKKAKETAGEQVLRLNNENEPTSFDPPIGFNNVSWQALNNLMEGLTRLGA
DHEPEAASAEKWNISDDGKTYTFTIRDDAKWSNGDPLTAGDFEYAWKRLLDPKTGSSAAFLGYFIEGGEAFNSGKGSKDD
VKVKAVDEKTLKVTLESPQQSFLSIVANPAFFPVPQKIAEDNPKWHEEAATFVGNGPFKLAEWKHDESFTMVKSDTYWDR
DTVKLDKVTWAMVDDRNTDYQMFESNELDTAYVPAEMSEKLMGSDEVKVFDQAGLYFYRFNVNKEPFQNEKIRKAFAMAV
DQQEIVDYVTKNGEKPARGFVSPGIKGPNGKDFREEGGDLLKYNADEAKQLLEKGMKEENYEKLPAVTLTYSTKPEHKKM
AEAVQQKLKSTLGVDVKLANMEWNTFLEEQKALKFQFSQSSFLADYADPINFLESFQTGNAMNRTGWGNSEYDELIKAAK
NEADEEKRTELLHQAEELLFEGMPIIPIHFYNQVHLEKENVKGIVRHPVGYIELKWAEKTS
>Mature_541_residues
MKRLTSVLASAFAVILLFGCTANEQAGQETKKKAKETAGEQVLRLNNENEPTSFDPPIGFNNVSWQALNNLMEGLTRLGA
DHEPEAASAEKWNISDDGKTYTFTIRDDAKWSNGDPLTAGDFEYAWKRLLDPKTGSSAAFLGYFIEGGEAFNSGKGSKDD
VKVKAVDEKTLKVTLESPQQSFLSIVANPAFFPVPQKIAEDNPKWHEEAATFVGNGPFKLAEWKHDESFTMVKSDTYWDR
DTVKLDKVTWAMVDDRNTDYQMFESNELDTAYVPAEMSEKLMGSDEVKVFDQAGLYFYRFNVNKEPFQNEKIRKAFAMAV
DQQEIVDYVTKNGEKPARGFVSPGIKGPNGKDFREEGGDLLKYNADEAKQLLEKGMKEENYEKLPAVTLTYSTKPEHKKM
AEAVQQKLKSTLGVDVKLANMEWNTFLEEQKALKFQFSQSSFLADYADPINFLESFQTGNAMNRTGWGNSEYDELIKAAK
NEADEEKRTELLHQAEELLFEGMPIIPIHFYNQVHLEKENVKGIVRHPVGYIELKWAEKTS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=505, Percent_Identity=33.0693069306931, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI87081878, Length=493, Percent_Identity=33.2657200811359, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1787495, Length=497, Percent_Identity=33.1991951710262, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1789966, Length=516, Percent_Identity=25.1937984496124, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787762, Length=549, Percent_Identity=24.5901639344262, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787052, Length=492, Percent_Identity=23.9837398373984, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=25, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1787551, Length=462, Percent_Identity=20.7792207792208, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61160; Mature: 61160

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLTSVLASAFAVILLFGCTANEQAGQETKKKAKETAGEQVLRLNNENEPTSFDPPIGF
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCC
NNVSWQALNNLMEGLTRLGADHEPEAASAEKWNISDDGKTYTFTIRDDAKWSNGDPLTAG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
DFEYAWKRLLDPKTGSSAAFLGYFIEGGEAFNSGKGSKDDVKVKAVDEKTLKVTLESPQQ
CHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHH
SFLSIVANPAFFPVPQKIAEDNPKWHEEAATFVGNGPFKLAEWKHDESFTMVKSDTYWDR
HHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCC
DTVKLDKVTWAMVDDRNTDYQMFESNELDTAYVPAEMSEKLMGSDEVKVFDQAGLYFYRF
CCEEEEEEEEEEECCCCCCCEEEECCCCCCEECCHHHHHHHCCCCCEEEEECCCEEEEEE
NVNKEPFQNEKIRKAFAMAVDQQEIVDYVTKNGEKPARGFVSPGIKGPNGKDFREEGGDL
ECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCE
LKYNADEAKQLLEKGMKEENYEKLPAVTLTYSTKPEHKKMAEAVQQKLKSTLGVDVKLAN
EEECHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEC
MEWNTFLEEQKALKFQFSQSSFLADYADPINFLESFQTGNAMNRTGWGNSEYDELIKAAK
CCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
NEADEEKRTELLHQAEELLFEGMPIIPIHFYNQVHLEKENVKGIVRHPVGYIELKWAEKT
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEHHHCCHHHHCCCCEEEEEECCCC
S
C
>Mature Secondary Structure
MKRLTSVLASAFAVILLFGCTANEQAGQETKKKAKETAGEQVLRLNNENEPTSFDPPIGF
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCC
NNVSWQALNNLMEGLTRLGADHEPEAASAEKWNISDDGKTYTFTIRDDAKWSNGDPLTAG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
DFEYAWKRLLDPKTGSSAAFLGYFIEGGEAFNSGKGSKDDVKVKAVDEKTLKVTLESPQQ
CHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHH
SFLSIVANPAFFPVPQKIAEDNPKWHEEAATFVGNGPFKLAEWKHDESFTMVKSDTYWDR
HHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCC
DTVKLDKVTWAMVDDRNTDYQMFESNELDTAYVPAEMSEKLMGSDEVKVFDQAGLYFYRF
CCEEEEEEEEEEECCCCCCCEEEECCCCCCEECCHHHHHHHCCCCCEEEEECCCEEEEEE
NVNKEPFQNEKIRKAFAMAVDQQEIVDYVTKNGEKPARGFVSPGIKGPNGKDFREEGGDL
ECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCE
LKYNADEAKQLLEKGMKEENYEKLPAVTLTYSTKPEHKKMAEAVQQKLKSTLGVDVKLAN
EEECHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEC
MEWNTFLEEQKALKFQFSQSSFLADYADPINFLESFQTGNAMNRTGWGNSEYDELIKAAK
CCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
NEADEEKRTELLHQAEELLFEGMPIIPIHFYNQVHLEKENVKGIVRHPVGYIELKWAEKT
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEHHHCCHHHHCCCCEEEEEECCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]