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The map label for this gene is ggt [H]

Identifier: 52785132

GI number: 52785132

Start: 1354666

End: 1356423

Strand: Direct

Name: ggt [H]

Synonym: BLi01364

Alternate gene names: 52785132

Gene position: 1354666-1356423 (Clockwise)

Preceding gene: 52785127

Following gene: 52785133

Centisome position: 32.08

GC content: 50.0

Gene sequence:

>1758_bases
ATGAGACGGTTAGCTTTCTTAGTTGTTGCGTTTTGCTTGGCGGTTGGTTGCTTTTTCAGTCCGGTGTCGAAAGCAGAAGG
AGTCATGAGCGGGGGAGATGGTGATAAAGTCGCCGTCGGGAAAGACGGTATGGTGGCTACGGCCCATCCGCTTGCATCAA
AAATCGGAGCCGAAGTTTTGAAAAAGGGCGGGAATGCCATTGATGCAGCTATTGCGATCCAGTACGCACTGAATGTAACA
GAGCCGATGATGTCTGGAATCGGCGGCGGCGGTTTCATGATGGTCTACGACGGCGAGACGAAGGAAACGTCGATCATCAA
CAGCAGGGAGCGTGCTCCGGAGGGAGCCAAGCCTGACATGTTTTTGGATGAAGACGGAAAGGTGATTCCGTTTTCAGAAA
GGTCGAGACACGGAAATGCGGTCGGTGTGCCGGGAACGCTGAAAGGGCTTGAAGCAGCGCATAAGAAGTGGGGAACAAAG
AAAATGGAAGACTTGATTTCGCCTTCTATAAAGCTTGCAGAGGAAGGGTTCCCAATCGACTCGGTTTTGGCTGACGCGAT
AAAGGATCATCAGGACAAGCTGAGCAAAACGGCCGCAAAGGATATTTTCCTTCCGGACGGTGAACCTTTGAAAGAAGGCG
ATATCCTTGTACAAAAGGATTTGGCCAAAACGTTTAAATTGATACGGAAAGAAGGGTCAAAAGCCTTTTATGATGGGGAA
ATCGGCCGGGCGATTGCAGATGTCGTGCAGGATTTCGGGGGTTCAATGACACCTGATGACCTGTCCCGCTACGAGGTCAC
AACAGATAAGCCCATCTGGGGCGAGTACCACGGCTATGATATTGCAAGCATGCCTCCTCCAAGCTCAGGCGGAGTGTTCA
TGCTGCAGATGCTGAAATTGATTGATGATTTTCATTTATCGCAATACGATCCAAAGTCGTTTGAAAAATATCATCTGCTC
GCGGAAACGATGCATCTCTCCTATGCGGACAGGGCTGCATATGCGGGCGATCCGGAATTTGTCGATGTTCCGCTCAGAGG
GCTGCTCGATCCCGATTATATTAAGGAGCGGCAAAAGCTGATCAGCCTTGATTCGATGAACCGCGATGTGAAAGAGGGCG
ATCCGTGGAAATATGAGGAAGGCGAGCCGAATTATGAGATCGTGCCTCAGCCTGAAGATAAAACGATCGGGGAGACGACG
CATTTTACCGTCACGGATCAGTGGGGCAATGTTGTCTCTTATACGACAACGATTGAACAGCTTTTTGGAACGGGGATTTT
AGTGCCCGGGTACGGACTGTTTTTGAACAATGAACTGACCGATTTTGATGCGATTCCAGGCGGCGCCAACGAAGTGCAGC
CGAATAAAAGGCCGCTTTCAAGCATGACGCCGACGATCGTATTCAAAGATGAAAAACCGGTGCTGACTGTCGGTTCCCCT
GGCGGAACGACGATCATTGCTTCCGTTTTCCAGACGATCTTGAATTATTTTGAGTACGGCATGAGCCTTCAGGATGCGAT
TGAAGAGCCGAGGATCTATACGAACAGCCTGACTTCGTACCGCTATGAATCCGGAATGCCGGAGGATGTCAGACGGAAGC
TCAATGACTTCGGCCACAAATTCGGCTCGAATCCGGTTGATATCGGCAATGTCCAAAGCATTTTCATTGACCGGGAGAAC
AAAACGTTTATGGGGGTTGCCGATTCAAGCAGAAACGGAACGGCGGTTGGGGTCAACATTAAGACATCGGCTAAATAG

Upstream 100 bases:

>100_bases
TGGGAGTTTAGGTTCAAAAAAATAGAAAATTGGGAGTTTTTCTTATTTTCAGTCCGCTTTCCTGTTATAGTAGTAATAAA
CTGGAAAGGAAGGTGATCTG

Downstream 100 bases:

>100_bases
CGGAGCAAGGCTTGGTCTAAAGTATTTAGATCAAGCCTTCTTCCGTCAGCGGGGAAAAGAGGATTTTTTTCGAAAGAATA
GAAATATATTTTTTGAAAGC

Product: Ggt

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAHPLASKIGAEVLKKGGNAIDAAIAIQYALNVT
EPMMSGIGGGGFMMVYDGETKETSIINSRERAPEGAKPDMFLDEDGKVIPFSERSRHGNAVGVPGTLKGLEAAHKKWGTK
KMEDLISPSIKLAEEGFPIDSVLADAIKDHQDKLSKTAAKDIFLPDGEPLKEGDILVQKDLAKTFKLIRKEGSKAFYDGE
IGRAIADVVQDFGGSMTPDDLSRYEVTTDKPIWGEYHGYDIASMPPPSSGGVFMLQMLKLIDDFHLSQYDPKSFEKYHLL
AETMHLSYADRAAYAGDPEFVDVPLRGLLDPDYIKERQKLISLDSMNRDVKEGDPWKYEEGEPNYEIVPQPEDKTIGETT
HFTVTDQWGNVVSYTTTIEQLFGTGILVPGYGLFLNNELTDFDAIPGGANEVQPNKRPLSSMTPTIVFKDEKPVLTVGSP
GGTTIIASVFQTILNYFEYGMSLQDAIEEPRIYTNSLTSYRYESGMPEDVRRKLNDFGHKFGSNPVDIGNVQSIFIDREN
KTFMGVADSSRNGTAVGVNIKTSAK

Sequences:

>Translated_585_residues
MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAHPLASKIGAEVLKKGGNAIDAAIAIQYALNVT
EPMMSGIGGGGFMMVYDGETKETSIINSRERAPEGAKPDMFLDEDGKVIPFSERSRHGNAVGVPGTLKGLEAAHKKWGTK
KMEDLISPSIKLAEEGFPIDSVLADAIKDHQDKLSKTAAKDIFLPDGEPLKEGDILVQKDLAKTFKLIRKEGSKAFYDGE
IGRAIADVVQDFGGSMTPDDLSRYEVTTDKPIWGEYHGYDIASMPPPSSGGVFMLQMLKLIDDFHLSQYDPKSFEKYHLL
AETMHLSYADRAAYAGDPEFVDVPLRGLLDPDYIKERQKLISLDSMNRDVKEGDPWKYEEGEPNYEIVPQPEDKTIGETT
HFTVTDQWGNVVSYTTTIEQLFGTGILVPGYGLFLNNELTDFDAIPGGANEVQPNKRPLSSMTPTIVFKDEKPVLTVGSP
GGTTIIASVFQTILNYFEYGMSLQDAIEEPRIYTNSLTSYRYESGMPEDVRRKLNDFGHKFGSNPVDIGNVQSIFIDREN
KTFMGVADSSRNGTAVGVNIKTSAK
>Mature_585_residues
MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAHPLASKIGAEVLKKGGNAIDAAIAIQYALNVT
EPMMSGIGGGGFMMVYDGETKETSIINSRERAPEGAKPDMFLDEDGKVIPFSERSRHGNAVGVPGTLKGLEAAHKKWGTK
KMEDLISPSIKLAEEGFPIDSVLADAIKDHQDKLSKTAAKDIFLPDGEPLKEGDILVQKDLAKTFKLIRKEGSKAFYDGE
IGRAIADVVQDFGGSMTPDDLSRYEVTTDKPIWGEYHGYDIASMPPPSSGGVFMLQMLKLIDDFHLSQYDPKSFEKYHLL
AETMHLSYADRAAYAGDPEFVDVPLRGLLDPDYIKERQKLISLDSMNRDVKEGDPWKYEEGEPNYEIVPQPEDKTIGETT
HFTVTDQWGNVVSYTTTIEQLFGTGILVPGYGLFLNNELTDFDAIPGGANEVQPNKRPLSSMTPTIVFKDEKPVLTVGSP
GGTTIIASVFQTILNYFEYGMSLQDAIEEPRIYTNSLTSYRYESGMPEDVRRKLNDFGHKFGSNPVDIGNVQSIFIDREN
KTFMGVADSSRNGTAVGVNIKTSAK

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=546, Percent_Identity=31.8681318681319, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI73915090, Length=546, Percent_Identity=31.8681318681319, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI73915096, Length=546, Percent_Identity=31.8681318681319, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI73915094, Length=546, Percent_Identity=31.8681318681319, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI113429326, Length=548, Percent_Identity=30.2919708029197, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI113429324, Length=543, Percent_Identity=30.0184162062615, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI153266885, Length=553, Percent_Identity=26.4014466546112, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI153266901, Length=554, Percent_Identity=26.3537906137184, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI109148539, Length=555, Percent_Identity=27.7477477477477, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI153266907, Length=553, Percent_Identity=25.1356238698011, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI30581157, Length=198, Percent_Identity=32.8282828282828, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI30581155, Length=198, Percent_Identity=32.8282828282828, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI218505805, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI310124095, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789856, Length=576, Percent_Identity=38.1944444444444, Blast_Score=371, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI212646519, Length=493, Percent_Identity=33.2657200811359, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI72000294, Length=494, Percent_Identity=33.1983805668016, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI193208247, Length=548, Percent_Identity=29.9270072992701, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI193208245, Length=548, Percent_Identity=29.9270072992701, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17542894, Length=516, Percent_Identity=31.3953488372093, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17506189, Length=521, Percent_Identity=29.9424184261036, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI72001497, Length=226, Percent_Identity=26.5486725663717, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI72001495, Length=226, Percent_Identity=26.5486725663717, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17564448, Length=438, Percent_Identity=27.1689497716895, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323330, Length=522, Percent_Identity=31.8007662835249, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI18859893, Length=520, Percent_Identity=32.1153846153846, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI161077880, Length=562, Percent_Identity=28.6476868327402, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI161077878, Length=562, Percent_Identity=28.6476868327402, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24642670, Length=561, Percent_Identity=28.698752228164, Blast_Score=198, Evalue=9e-51,
Organism=Drosophila melanogaster, GI24642666, Length=561, Percent_Identity=28.698752228164, Blast_Score=198, Evalue=9e-51,
Organism=Drosophila melanogaster, GI45551474, Length=561, Percent_Identity=28.698752228164, Blast_Score=198, Evalue=9e-51,
Organism=Drosophila melanogaster, GI161077496, Length=558, Percent_Identity=28.1362007168459, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI18859741, Length=516, Percent_Identity=27.5193798449612, Blast_Score=150, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 63975; Mature: 63975

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00063 ALDOKETO_REDUCTASE_3 ; PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAHPLASKIGAEVL
CHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHH
KKGGNAIDAAIAIQYALNVTEPMMSGIGGGGFMMVYDGETKETSIINSRERAPEGAKPDM
HCCCCCHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCHHHHCCHHCCCCCCCCCE
FLDEDGKVIPFSERSRHGNAVGVPGTLKGLEAAHKKWGTKKMEDLISPSIKLAEEGFPID
EECCCCCEECCCCCCCCCCEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCHH
SVLADAIKDHQDKLSKTAAKDIFLPDGEPLKEGDILVQKDLAKTFKLIRKEGSKAFYDGE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCH
IGRAIADVVQDFGGSMTPDDLSRYEVTTDKPIWGEYHGYDIASMPPPSSGGVFMLQMLKL
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
IDDFHLSQYDPKSFEKYHLLAETMHLSYADRAAYAGDPEFVDVPLRGLLDPDYIKERQKL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHCCCHHHHHHHHHH
ISLDSMNRDVKEGDPWKYEEGEPNYEIVPQPEDKTIGETTHFTVTDQWGNVVSYTTTIEQ
HHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHH
LFGTGILVPGYGLFLNNELTDFDAIPGGANEVQPNKRPLSSMTPTIVFKDEKPVLTVGSP
HHCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCC
GGTTIIASVFQTILNYFEYGMSLQDAIEEPRIYTNSLTSYRYESGMPEDVRRKLNDFGHK
CCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCHHHHHHCCCCCHHHHHHHHHHHHH
FGSNPVDIGNVQSIFIDRENKTFMGVADSSRNGTAVGVNIKTSAK
HCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAHPLASKIGAEVL
CHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHH
KKGGNAIDAAIAIQYALNVTEPMMSGIGGGGFMMVYDGETKETSIINSRERAPEGAKPDM
HCCCCCHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCHHHHCCHHCCCCCCCCCE
FLDEDGKVIPFSERSRHGNAVGVPGTLKGLEAAHKKWGTKKMEDLISPSIKLAEEGFPID
EECCCCCEECCCCCCCCCCEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCHH
SVLADAIKDHQDKLSKTAAKDIFLPDGEPLKEGDILVQKDLAKTFKLIRKEGSKAFYDGE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCH
IGRAIADVVQDFGGSMTPDDLSRYEVTTDKPIWGEYHGYDIASMPPPSSGGVFMLQMLKL
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
IDDFHLSQYDPKSFEKYHLLAETMHLSYADRAAYAGDPEFVDVPLRGLLDPDYIKERQKL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHCCCHHHHHHHHHH
ISLDSMNRDVKEGDPWKYEEGEPNYEIVPQPEDKTIGETTHFTVTDQWGNVVSYTTTIEQ
HHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHH
LFGTGILVPGYGLFLNNELTDFDAIPGGANEVQPNKRPLSSMTPTIVFKDEKPVLTVGSP
HHCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCC
GGTTIIASVFQTILNYFEYGMSLQDAIEEPRIYTNSLTSYRYESGMPEDVRRKLNDFGHK
CCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCHHHHHHCCCCCHHHHHHHHHHHHH
FGSNPVDIGNVQSIFIDRENKTFMGVADSSRNGTAVGVNIKTSAK
HCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA