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The map label for this gene is yjjN [H]

Identifier: 52785126

GI number: 52785126

Start: 1349049

End: 1350062

Strand: Direct

Name: yjjN [H]

Synonym: BLi01358

Alternate gene names: 52785126

Gene position: 1349049-1350062 (Clockwise)

Preceding gene: 52785125

Following gene: 52785127

Centisome position: 31.95

GC content: 51.28

Gene sequence:

>1014_bases
ATGAAGCAGATTGTGTGTGAAAAGCCTTATCGTTTTAAAATGACGGATGTGAAAATGCCGGAACTAAAGGATGGGGAAGC
ATTGGTCCGCATCAAACGGATCGGAATATGCGGGACGGATTTTCACGCTTATTGCGGAAGACAGCCATTTTTCTCTTATC
CAAGAGTGCTCGGACACGAACTGTCCGGTGAAATTGTCAGCATCGATAATTCCGGCGGAACGCTCAAGCCGGGCGATCAA
GTGTCAATTATTCCTTATTTGGAATGCGGGGCATGCATCGCCTGCCGGAACGGACGCCCCAACTGCTGCGTCAATCTGAA
CGTCCTCGGTGTCCATACAGACGGGGGAATGCGGGAATACATAAACGTCCCGGCAGACCACCTGCTAAAAACAGAAGGAT
TGACGCTCAGCGAAGCTGCTGTTGTTGAATGTTTAAGCATCGGCGCCCACGCTGCAGAAAGGGCAAATATCAAAAAAGGG
GAAACGGTGCTTGTTGTTGGAGCGGGGCCCATCGGGCTCAGCGTGATGAAATTCGCAAAATTGAAGGGTGCAAAAGTCAT
CGCGATGGATGTCAGAAAAGAGCGCCTCACATTTAGCCGCAGATGGGCTGAAGCCGATGAAGTCGTATTAGGGGGAGAAC
ATGCGGCTGATGAGATCAAACGGTTGACGAACGGCGACTTTCCGACGGCTGTCTTTGATGCGACAGGGCACCCTGCATCG
ATGAACAGCGCTTATCAGTACGCCGCACACGGGGGACGGCTGATCTATGTCGGACTTGTCAACGACCATCTGGCTATGCC
CGATCCTGAAATCCACATGCGGGAGCTGACGATTTTATCCAGCCGCAACGCATTAAGAAGAGATTTTGAGACGGTGATGA
AAGCCATCATGGATGGCGGAGCGGATGCGAACCGGTTTGTGAACGGACAGATGGCGTTTCACGATGTTGTTGACGGATTT
CAATCAGCGCTTGCTCCGGAAACCAATCCTGTGAAAGTGTTGATCCATCTGTAA

Upstream 100 bases:

>100_bases
AGAAGATGTCCGGATTTGTTACCGGCATAACAGTGCCGGTAGATGGCGGATTTACGGCTTATGCCGGTGTCTAAAAACAC
GATAAAGGGGAGGCCGGTAC

Downstream 100 bases:

>100_bases
GATCGCACGAAATGAAAGCGTTTTCTAAATTTCGGAAAGAGGGGGGTTGGCCATGTTTTCAAACGGCCGCGGGTTTGTCA
TCGTGATGCTTTTTTTGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKQIVCEKPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAYCGRQPFFSYPRVLGHELSGEIVSIDNSGGTLKPGDQ
VSIIPYLECGACIACRNGRPNCCVNLNVLGVHTDGGMREYINVPADHLLKTEGLTLSEAAVVECLSIGAHAAERANIKKG
ETVLVVGAGPIGLSVMKFAKLKGAKVIAMDVRKERLTFSRRWAEADEVVLGGEHAADEIKRLTNGDFPTAVFDATGHPAS
MNSAYQYAAHGGRLIYVGLVNDHLAMPDPEIHMRELTILSSRNALRRDFETVMKAIMDGGADANRFVNGQMAFHDVVDGF
QSALAPETNPVKVLIHL

Sequences:

>Translated_337_residues
MKQIVCEKPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAYCGRQPFFSYPRVLGHELSGEIVSIDNSGGTLKPGDQ
VSIIPYLECGACIACRNGRPNCCVNLNVLGVHTDGGMREYINVPADHLLKTEGLTLSEAAVVECLSIGAHAAERANIKKG
ETVLVVGAGPIGLSVMKFAKLKGAKVIAMDVRKERLTFSRRWAEADEVVLGGEHAADEIKRLTNGDFPTAVFDATGHPAS
MNSAYQYAAHGGRLIYVGLVNDHLAMPDPEIHMRELTILSSRNALRRDFETVMKAIMDGGADANRFVNGQMAFHDVVDGF
QSALAPETNPVKVLIHL
>Mature_337_residues
MKQIVCEKPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAYCGRQPFFSYPRVLGHELSGEIVSIDNSGGTLKPGDQ
VSIIPYLECGACIACRNGRPNCCVNLNVLGVHTDGGMREYINVPADHLLKTEGLTLSEAAVVECLSIGAHAAERANIKKG
ETVLVVGAGPIGLSVMKFAKLKGAKVIAMDVRKERLTFSRRWAEADEVVLGGEHAADEIKRLTNGDFPTAVFDATGHPAS
MNSAYQYAAHGGRLIYVGLVNDHLAMPDPEIHMRELTILSSRNALRRDFETVMKAIMDGGADANRFVNGQMAFHDVVDGF
QSALAPETNPVKVLIHL

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=285, Percent_Identity=32.280701754386, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI262073058, Length=354, Percent_Identity=25.1412429378531, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI71743840, Length=354, Percent_Identity=25.1412429378531, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4501939, Length=214, Percent_Identity=29.9065420560748, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI156523966, Length=214, Percent_Identity=29.9065420560748, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4501929, Length=220, Percent_Identity=28.6363636363636, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI34577061, Length=222, Percent_Identity=30.6306306306306, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI71565154, Length=351, Percent_Identity=24.7863247863248, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4501933, Length=222, Percent_Identity=28.8288288288288, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI226510992, Length=321, Percent_Identity=40.1869158878505, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1787863, Length=341, Percent_Identity=33.4310850439883, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1790045, Length=325, Percent_Identity=30.1538461538462, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788073, Length=345, Percent_Identity=27.8260869565217, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788407, Length=289, Percent_Identity=29.0657439446367, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87081918, Length=304, Percent_Identity=29.2763157894737, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082125, Length=260, Percent_Identity=30, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1790718, Length=306, Percent_Identity=27.7777777777778, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786552, Length=351, Percent_Identity=26.7806267806268, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786825, Length=227, Percent_Identity=29.0748898678414, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788075, Length=301, Percent_Identity=24.5847176079734, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562876, Length=338, Percent_Identity=27.5147928994083, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17562878, Length=323, Percent_Identity=28.1733746130031, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988145, Length=262, Percent_Identity=25.1908396946565, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562584, Length=295, Percent_Identity=26.7796610169492, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562582, Length=295, Percent_Identity=26.4406779661017, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146526, Length=308, Percent_Identity=25.3246753246753, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71997431, Length=277, Percent_Identity=25.2707581227437, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323099, Length=344, Percent_Identity=28.7790697674419, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322619, Length=350, Percent_Identity=27.4285714285714, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319955, Length=350, Percent_Identity=27.1428571428571, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320033, Length=359, Percent_Identity=28.133704735376, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319257, Length=333, Percent_Identity=27.027027027027, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=359, Percent_Identity=24.7910863509749, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=271, Percent_Identity=27.3062730627306, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=267, Percent_Identity=29.5880149812734, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=305, Percent_Identity=28.1967213114754, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=195, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17737897, Length=337, Percent_Identity=27.893175074184, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI17137530, Length=330, Percent_Identity=29.0909090909091, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI221457811, Length=326, Percent_Identity=23.3128834355828, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45550770, Length=326, Percent_Identity=23.3128834355828, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45551930, Length=326, Percent_Identity=23.3128834355828, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17737895, Length=299, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36689; Mature: 36689

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIVCEKPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAYCGRQPFFSYPRVLGHE
CCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECEECCCHHHHCCCCCCCCCHHHHHHC
LSGEIVSIDNSGGTLKPGDQVSIIPYLECGACIACRNGRPNCCVNLNVLGVHTDGGMREY
CCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEECCCCCCEEEEEEEEEEECCCCHHHH
INVPADHLLKTEGLTLSEAAVVECLSIGAHAAERANIKKGETVLVVGAGPIGLSVMKFAK
HCCCHHHHEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LKGAKVIAMDVRKERLTFSRRWAEADEVVLGGEHAADEIKRLTNGDFPTAVFDATGHPAS
HCCCEEEEEECHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
MNSAYQYAAHGGRLIYVGLVNDHLAMPDPEIHMRELTILSSRNALRRDFETVMKAIMDGG
CCCHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCC
ADANRFVNGQMAFHDVVDGFQSALAPETNPVKVLIHL
CCHHHEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MKQIVCEKPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAYCGRQPFFSYPRVLGHE
CCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECEECCCHHHHCCCCCCCCCHHHHHHC
LSGEIVSIDNSGGTLKPGDQVSIIPYLECGACIACRNGRPNCCVNLNVLGVHTDGGMREY
CCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEECCCCCCEEEEEEEEEEECCCCHHHH
INVPADHLLKTEGLTLSEAAVVECLSIGAHAAERANIKKGETVLVVGAGPIGLSVMKFAK
HCCCHHHHEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LKGAKVIAMDVRKERLTFSRRWAEADEVVLGGEHAADEIKRLTNGDFPTAVFDATGHPAS
HCCCEEEEEECHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
MNSAYQYAAHGGRLIYVGLVNDHLAMPDPEIHMRELTILSSRNALRRDFETVMKAIMDGG
CCCHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCC
ADANRFVNGQMAFHDVVDGFQSALAPETNPVKVLIHL
CCHHHEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]