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The map label for this gene is yyaH [H]

Identifier: 52785075

GI number: 52785075

Start: 1308943

End: 1309320

Strand: Direct

Name: yyaH [H]

Synonym: BLi01307

Alternate gene names: 52785075

Gene position: 1308943-1309320 (Clockwise)

Preceding gene: 52785074

Following gene: 52785077

Centisome position: 31.0

GC content: 46.56

Gene sequence:

>378_bases
ATGAAAATCGAACACATCGCCATATGGACGAACAATTTAGAGGAAATGAAAGATTTCTATACCCGTTTTTTTCACGGAAA
GACGAATGAAAAATATGTCAATCCGAAAAAGCATTTCGAATCATATTTCATCCAGTTTGAATCGGGAACACGGCTTGAGC
TGATGAGACGCCCCGACCTTGCAAAAGGAGAGGAGAACGCTTCCGGCTATGCACATATGGCGTTTTCCTTAGGGTCGCGG
CAAGAGGTTGACGAGATGACGAGCCGCTTTGAAAAGGAAGGATACCAGGTTGCCGGAAAGCCGCGCGTCACGGGAGACGG
GTATTATGAAAGAGTCATTCTGGATCCTGACGGCAACATCGTTGAACTGACCGTTTGA

Upstream 100 bases:

>100_bases
TCATGATCTGCATCGGCATTTTTATGAATACTTATCAATTTAAAAAAGTGTAAAAAAAGGCAGAGGATCTATATGGTAAT
ATGAAATGGGAGGGAGATTT

Downstream 100 bases:

>100_bases
CGGAAAAAAGCTAATGTCCGTTTTTAGACATTAGCTTTTTCGTTTAGATGGCAGCATCGAGCTGATTGATTTTCCATTTG
TTGTTTTCTTTCACAAACGT

Product: YyaH

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKIEHIAIWTNNLEEMKDFYTRFFHGKTNEKYVNPKKHFESYFIQFESGTRLELMRRPDLAKGEENASGYAHMAFSLGSR
QEVDEMTSRFEKEGYQVAGKPRVTGDGYYERVILDPDGNIVELTV

Sequences:

>Translated_125_residues
MKIEHIAIWTNNLEEMKDFYTRFFHGKTNEKYVNPKKHFESYFIQFESGTRLELMRRPDLAKGEENASGYAHMAFSLGSR
QEVDEMTSRFEKEGYQVAGKPRVTGDGYYERVILDPDGNIVELTV
>Mature_125_residues
MKIEHIAIWTNNLEEMKDFYTRFFHGKTNEKYVNPKKHFESYFIQFESGTRLELMRRPDLAKGEENASGYAHMAFSLGSR
QEVDEMTSRFEKEGYQVAGKPRVTGDGYYERVILDPDGNIVELTV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14609; Mature: 14609

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEHIAIWTNNLEEMKDFYTRFFHGKTNEKYVNPKKHFESYFIQFESGTRLELMRRPDL
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCEEEEEECCCC
AKGEENASGYAHMAFSLGSRQEVDEMTSRFEKEGYQVAGKPRVTGDGYYERVILDPDGNI
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCCCE
VELTV
EEEEC
>Mature Secondary Structure
MKIEHIAIWTNNLEEMKDFYTRFFHGKTNEKYVNPKKHFESYFIQFESGTRLELMRRPDL
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCEEEEEECCCC
AKGEENASGYAHMAFSLGSRQEVDEMTSRFEKEGYQVAGKPRVTGDGYYERVILDPDGNI
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCCCE
VELTV
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]