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The map label for this gene is mecA [H]

Identifier: 52785011

GI number: 52785011

Start: 1252370

End: 1253008

Strand: Direct

Name: mecA [H]

Synonym: BLi01240

Alternate gene names: 52785011

Gene position: 1252370-1253008 (Clockwise)

Preceding gene: 52785010

Following gene: 52785012

Centisome position: 29.66

GC content: 41.16

Gene sequence:

>639_bases
ATGGAAATCGAAAGAATAAACGAACACACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGACAAGGGATTGGAAATCATTGTGACAAGAGCTCAGTTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAATTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTGTCAGCGGTTGCCAAACGACATTGTACTCTCATGAAAACCGCTATTATTTATTCGTG
GATTTCAATGAACTGCCTGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAATATGCCTCAGAATCAAAGATGAC
GATTCATATGCTGAAAGAGTATGGAAAACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTTGCATAA

Upstream 100 bases:

>100_bases
AGGTTAAGAAGTGGACGTAATGGGTAAAGTGTAGTAAAGTACAATTAATTGGGAGCTTAGTTATCCCTTCAACATCTTAC
AAAGAAGGGAAGGTTGGCAA

Downstream 100 bases:

>100_bases
AAAAGCCGGTTTCCTTTGAAGCCGGCTTTAACCTTCTCCATTACGGGGAAGGTTTTTTTGTGAACTTTATGAACAAAAAG
AATATTATGCAGTTAAACTG

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFV
DFNELPDEEVENQLSILLEYASESKMTIHMLKEYGKLIAADHALHTIKKHFA

Sequences:

>Translated_212_residues
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFV
DFNELPDEEVENQLSILLEYASESKMTIHMLKEYGKLIAADHALHTIKKHFA
>Mature_212_residues
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFV
DFNELPDEEVENQLSILLEYASESKMTIHMLKEYGKLIAADHALHTIKKHFA

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 25115; Mature: 25115

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPL
CCCCCCCCEEEEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHEEECCCE
WIQVQALDKGLEIIVTRAQLSKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQ
EEEEEECCCCCEEEEEHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFVDFNELPDEEVENQLSILLEY
HHEEEEEECCHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCHHHHHHHHHHHHH
ASESKMTIHMLKEYGKLIAADHALHTIKKHFA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPL
CCCCCCCCEEEEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHEEECCCE
WIQVQALDKGLEIIVTRAQLSKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQ
EEEEEECCCCCEEEEEHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFVDFNELPDEEVENQLSILLEY
HHEEEEEECCHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCHHHHHHHHHHHHH
ASESKMTIHMLKEYGKLIAADHALHTIKKHFA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412687; 9384377 [H]